Genomic profiling of Morganella morganii: insights into antibiotic resistance genes, pathogenicity islands, and toxin-antitoxin systems [0.03%]
Tosin Yetunde Senbadejo,Christina R Bourne,Abiola Isawumi
Tosin Yetunde Senbadejo
Morganella morganii is an opportunistic pathogen affecting immunocompromised and hospitalized intensive care patients. It colonizes diverse environments and exhibits multidrug resistance. Its genome encodes factors that impart pathogenicity...
Genomic, proteolytic, and phenotypic characterization of Pseudomonas aeruginosa isolates causing infective endocarditis [0.03%]
Sarah M Hickson,Von Vergel L Torres,Jing Jie Teh et al.
Sarah M Hickson et al.
Infective endocarditis (IE) remains a formidable clinical challenge, characterized by high morbidity and mortality despite advances in antimicrobial therapy and surgery. Pseudomonas aeruginosa is an increasingly relevant IE pathogen due to ...
Establishment and application of a vesicle extraction method for clinical strains of Pseudomonas aeruginosa [0.03%]
Tania Henriquez,Francesco Santoro,Lorenzo Colombini et al.
Tania Henriquez et al.
Pseudomonas aeruginosa is a versatile pathogen capable of causing illnesses that range from mild infections to life-threatening conditions. Its virulence is driven by a wide array of factors, among which extracellular vesicles (EVs) have ga...
Adjuvant Lactiplantibacillus plantarum Lp05 modulates gut microbiota and alleviates symptoms during Helicobacter pylori eradication [0.03%]
Yuru Fu,Jie Dong,Leyi Xu et al.
Yuru Fu et al.
Helicobacter pylori eradication therapy is often accompanied by gastrointestinal adverse effects and gut microbiota dysbiosis. The role of specific probiotic strains in mitigating these issues requires further clinical evidence. In a random...
Clinical characteristics, risk factors, and pathogen spectrum of mixed infections in children with Mycoplasma pneumoniae pneumonia: a retrospective cohort study of 1,428 cases from a children's medical centre in East China [0.03%]
Cheng Wang,Shenghao Hua,Yang Li et al.
Cheng Wang et al.
This study aimed to investigate the clinical characteristics, risk factors, and pathogen spectrum of mixed infections in children with Mycoplasma pneumoniae pneumonia (MPP). A total of 1,428 pediatric MPP patients were retrospectively inclu...
WormSpot: a machine learning-powered viability scoring platform in C. elegans for Candida pathogenicity studies [0.03%]
Jonathan Guo Wei Lee,Victor Eng Yong Ong,Dan Zhang
Jonathan Guo Wei Lee
Invasive Candida infections pose a critical health challenge, exacerbated by emerging antifungal resistance. Caenorhabditis elegans (C. elegans) offers a genetically tractable and scalable model for studying Candida pathogenicity, yet conve...
Han Yan,Qianying Jia,Jing Liu et al.
Han Yan et al.
Functional constipation (FC) is a common gastrointestinal disorder that can seriously affect patients' quality of life. Probiotics have emerged as a promising strategy for preventing and managing gastrointestinal diseases. Previously, we is...
Quantification of the coupled dynamics of marine microbes and reactive oxygen species in laboratory batch culture experiments [0.03%]
Donna K McCullough,Emily C Bowden,Benjamin C Calfee et al.
Donna K McCullough et al.
Prochlorococcus, the smallest and most numerous phytoplankter of the oligotrophic surface ocean, is vulnerable to damage by the reactive oxygen species hydrogen peroxide (H2O2). The most harmful effects of exogenous H2O2 are mitigated by de...
Microbiota variation in Aedes aegypti (Diptera:Culicidae): a comparative study of field-caught and laboratory-adapted reared populations [0.03%]
Abelgie Sánchez-Amézquita,David Martínez,Omar Cantillo-Barraza et al.
Abelgie Sánchez-Amézquita et al.
The control of Aedes aegypti, the main vector of Dengue, Zika, and Chikungunya, remains a global health priority due to its expanding distribution and the absence of specific treatments. The mosquito's microbiota is increasingly recognized ...
Evaluation of the high-throughput RespiV PlexPlus multiplex assay compared to BioFire Respiratory Panel 2.1 plus [0.03%]
Todd M Pryce,Erin J Haygarth,Angelica S Lacsina et al.
Todd M Pryce et al.
During the 2023 Australian winter respiratory virus season, 2,000 clinical samples were prospectively tested over 47 days (July-August 2023) using the BioFire Respiratory Panel 2.1 plus (RP2.1+) assay, which detects 19 viral and 4 bacterial...