Retraction Notice to: circ_001653 Silencing Promotes the Proliferation and ECM Synthesis of NPCs in IDD by Downregulating miR-486-3p-Mediated CEMIP [0.03%]
有关于：circ_001653沉默通过下调miR-486-3p介导的CEMIP促进IDD中NPCs的增殖和ECM合成的撤稿通知
Shaoqian Cui,Lei Zhang
Shaoqian Cui
[This retracts the article DOI: 10.1016/j.omtn.2020.01.026.]. © 2023.
Retraction of Publication
Molecular therapy. Nucleic acids. 2023 Jan 27:31:352. DOI:10.1016/j.omtn.2023.01.012 2023
MDM2 antagonists promote CRISPR/Cas9-mediated precise genome editing in sheep primary cells [0.03%]
MDM2拮抗剂促进CRISPR / Cas9在羊原代细胞中的精准基因组编辑
Yan Li,Di Lian,Jiahao Wang et al.
Yan Li et al.
CRISPR-Cas9-mediated genome editing in sheep is of great use in both agricultural and biomedical applications. While targeted gene knockout by CRISPR-Cas9 through non-homologous end joining (NHEJ) has worked efficiently, the knockin efficie...
Internal m7G methylation: A novel epitranscriptomic contributor in brain development and diseases [0.03%]
脑内m7G甲基化：一种新的表转录组参与者在大脑发育和疾病中的作用
Xiaohuan Xia,Yi Wang,Jialin C Zheng
Xiaohuan Xia
In recent years, N7-methylguanosine (m7G) methylation, originally considered as messenger RNA (mRNA) 5' caps modifications, has been identified at defined internal positions within multiple types of RNAs, including transfer RNAs, ribosomal ...
Inducible miR-1224 silences cerebrovascular Serpine1 and restores blood flow to the stroke-affected site of the brain [0.03%]
诱导型miR-1224沉默脑血管Serpine1并恢复脑卒中影响区域的血液流量
Ravichand Palakurti,Nirupam Biswas,Sashwati Roy et al.
Ravichand Palakurti et al.
The α-tocotrienol (TCT) form of natural vitamin E is more potent than the better known α-tocopherol against stroke. Angiographic studies of canine stroke have revealed beneficial cerebrovascular effects of TCT. This work seeks to understa...
Broadly neutralizing aptamers to SARS-CoV-2: A diverse panel of modified DNA antiviral agents [0.03%]
针对SARS-CoV-2的广谱中和适配子：一系列多样化的抗病毒DNA修饰剂
Amy D Gelinas,Tiong Kit Tan,Sai Liu et al.
Amy D Gelinas et al.
Since its discovery, COVID-19 has rapidly spread across the globe and has had a massive toll on human health, with infection mortality rates as high as 10%, and a crippling impact on the world economy. Despite numerous advances, there remai...
Subretinal gene therapy delays vision loss in a Bardet-Biedl Syndrome type 10 mouse model [0.03%]
视网膜下基因治疗可延缓Bardet-Biedl综合征10型小鼠模型的视力丧失
Ying Hsu,Sajag Bhattarai,Jacob M Thompson et al.
Ying Hsu et al.
Blindness in Bardet-Biedl syndrome (BBS) is caused by dysfunction and loss of photoreceptor cells in the retina. BBS10, mutations of which account for approximately 21% of all BBS cases, encodes a chaperonin protein indispensable for the as...
Long non-coding RNA lnc-CHAF1B-3 promotes renal interstitial fibrosis by regulating EMT-related genes in renal proximal tubular cells [0.03%]
长非编码RNA lnc-CHAF1B-3通过调节肾近端小管细胞中EMT相关基因促进肾间质纤维化
Kentaro Imai,Takuji Ishimoto,Tomohito Doke et al.
Kentaro Imai et al.
Renal interstitial fibrosis (RIF) is a common pathological manifestation of chronic kidney diseases. Epithelial-mesenchymal transition (EMT) of tubular epithelial cells is considered a major cause of RIF. Although long non-coding RNAs (lncR...
Change of intracellular calcium level causes acute neurotoxicity by antisense oligonucleotides via CSF route [0.03%]
脑室内注射反义寡核苷酸引起细胞内钙离子水平改变及急性神经毒性作用
Chunyan Jia,Su Su Lei Mon,Ying Yang et al.
Chunyan Jia et al.
Antisense oligonucleotides (ASOs) are promising therapeutics for intractable central nervous system (CNS) diseases. For this clinical application, neurotoxicity is one of the critical limitations. Therefore, an evaluation of this neurotoxic...
Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling [0.03%]
G蛋白信号调节因子12通过MYCBP2/KIF2A信号激活滑膜成纤维细胞驱动炎性关节炎
Gongsheng Yuan,Shu-Ting Yang,Shuying Yang
Gongsheng Yuan
Synovial fibroblasts are the active and aggressive drivers in the progression of arthritis, but the cellular and molecular mechanisms remain unknown. Here, our results showed that regulator of G protein signaling 12 (RGS12) maintained cilio...
Erratum: Binding characterization of anthraquinone derivatives by stabilizing G-quadruplex DNA leads to an anticancerous activity [0.03%]
Correction: 抗癌活性通过稳定G-四链体DNA结合蒽醌衍生物的特性研究
Arpita Dey,Kumud Pandav,Mala Nath et al.
Arpita Dey et al.
[This corrects the article DOI: 10.1016/j.omtn.2022.11.008.]. © 2022.
Published Erratum
Molecular therapy. Nucleic acids. 2023 Jan 10:31:256. DOI:10.1016/j.omtn.2022.12.013 2023