Alpha-defensins promote macrophage inflammatory activation via RNF31 signaling [0.03%]
α-防御素通过RNF31信号促进巨噬细胞炎症激活
Jungnam Lee,Naweed Mohammad,Seyoung Mun et al.
Jungnam Lee et al.
Background: Defensins, small cationic peptides with strong antimicrobial activity, are key effectors of innate immunity. α-defensins, human neutrophil peptides, are produced primarily by neutrophils and serve as an essen...
Biomarkers for predominantly inattentive ADHD: potential involvement of Wnt/β-catenin/integrin signaling in a spontaneously hypertensive rat [0.03%]
以自发性高血压大鼠模型探讨多动症注意力缺陷为主型的生物标记物及其Wnt/β-catenin/整合素信号通路之可能涉及
Nicole Bon Campomayor,Sweetie Balataria,Kwang Hee Kim et al.
Nicole Bon Campomayor et al.
Background: Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder marked by heterogeneous symptoms and comorbidities, complicating diagnosis and obscuring its neurobiological basis. ...
TSTA3 promotes the malignant progression of bladder cancer by regulating LAMP2 and MAPK signaling pathway-mediated epithelial-mesenchymal transition [0.03%]
TSTA3通过调节LAMP2和MAPK信号通路介导的上皮间质转化促进膀胱癌恶性进展
Nihao Cao,Fei Cheng
Nihao Cao
Background: Bladder cancer (BCa) is the most frequently seen malignancy of the urinary tract. However, its molecular mechanisms and therapeutic targets are not well established. ...
Lasting bone marrow defects imprinted by hyperglycemia shape the immunological characteristics of differentiated M1 and M2 macrophages [0.03%]
高血糖印记的持久性骨髓缺陷塑造了M1和M2型巨噬细胞免疫学特征
In-Gu Lee,Jeonghyeon Lee,Ji Young Bang et al.
In-Gu Lee et al.
Background: Hyperglycemia in type 1 diabetes (T1D) disrupts immune function, yet it remains unclear whether hyperglycemia-induced immunological defects in the bone marrow (BM) persist in BM-derived M1 and M2 macrophages. ...
Transcriptomic signatures of pregnancy progression and potential early diagnostic biomarkers in peripheral blood of Hanwoo (Bos taurus coreanae) cattle [0.03%]
韩牛（Bos taurus coreanae）血液中妊娠进程的转录组特征及潜在早期诊断生物标志物
Junhyeon Jeon,Dong-Yep Oh,Wooseok Lee et al.
Junhyeon Jeon et al.
Background: Understanding the molecular regulation of gestation is crucial for improving reproductive efficiency in Hanwoo cattle, yet the systemic changes occurring throughout pregnancy remain undefined. ...
Genome-wide identification and expression analysis of the Hsf gene family in Rhododendron molle under heat stress [0.03%]
热应激下杜鹃花Hsf基因家族的全基因组鉴定及表达分析
Jieyu Peng,Shida Xu,Fanyu Zeng et al.
Jieyu Peng et al.
Background: Rhododendron possesses significant ornamental and economic value; however, its limited heat tolerance severely hinders its broader development and application. Heat shock transcription factors (Hsfs) are exten...
Identification of a novel nonsense variant in ARR3 in a family with early-onset high myopia [0.03%]
早发性高度近视家系中新型无义突变ARR3的鉴定
Jiahe Yu,Jie Zhang,Yaqin Jiang et al.
Jiahe Yu et al.
Integrative transcriptomics defines CD36 as a key regulator of immunometabolic signaling in acute myeloid leukemia [0.03%]
整合转录组学定义了CD36作为急性髓系白血病中免疫代谢信号的关键调节因子
Muhammad Sameer Ashaq,Qian Zhou,Yanxia Li et al.
Muhammad Sameer Ashaq et al.
Background: Acute myeloid leukemia (AML) is characterized by extensive immunometabolic rewiring that drives leukemic progression and fosters immune evasion. ...
Transcriptomic exploration unveils hub genes influencing fatty acid composition across various sections of yak meat [0.03%]
转录组学探索发现了影响牦牛肉各部位脂肪酸组成的关键基因
Bo Hu,Haiyue Wu,Rong Hu et al.
Bo Hu et al.
Prevalence of germline 113 cancer genes in healthy Indonesian hospital staff [0.03%]
印度尼西亚医院员工中113种癌症相关基因的携带率
Mega Hayati,Fahreza Saputra,Hubertus Hosti Hayuanta et al.
Mega Hayati et al.