Lasting bone marrow defects imprinted by hyperglycemia shape the immunological characteristics of differentiated M1 and M2 macrophages
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Background: Hyperglycemia in type 1 diabetes (T1D) disrupts immune function, yet it remains unclear whether hyperglycemia-induced immunological defects in the bone marrow (BM) persist in BM-derived M1 and M2 macrophages. ... ...