Current State of the Neurotrophin-Based Pharmaceutics in the Treatment of Neurodegenerative Diseases and Neuroinflammation [0.03%]
神经营养因子类药物治疗神经退行性疾病和神经炎症的现状
Tatiana A Fedotcheva,Nikolay L Shimanovsky
Tatiana A Fedotcheva
Background: The regulation of the synthesis of the nerve growth factor and other neurotrophins is one of the dynamically developing areas of pharmacotherapy of neurological and mental disorders. Despite a large number of ...
Seronegative Rheumatoid Arthritis: A Distinct Immunopathological Entity with Erosive Potential [0.03%]
血清阴性类风湿关节炎具有侵蚀潜能的免疫病理学实体
Florent Lhotellerie,Ala Eddine Ben Ismail,Julie Sarrand et al.
Florent Lhotellerie et al.
Background: Seronegative rheumatoid arthritis (SNRA), defined by the absence of rheumatoid factor (RF) and anti-citrullinated peptide antibodies (ACPA), represents 20-30% of rheumatoid arthritis cases. Once considered a milder phenotype, SN...
Validation of an ICD-9-CM-Based Monitoring Tool for Regional Trauma Systems: The PaTraME Study in Pavia Province, Italy [0.03%]
基于ICD-9-CM的区域创伤系统监测工具在意大利帕维亚省创伤管理系统中的验证：PaTraME研究
Paola Fugazzola,Leandro Gentile,Francesco Chiarolanza et al.
Paola Fugazzola et al.
Background/Objectives: Continuous trauma-system monitoring is limited by the lack of scalable, low-cost tools. The Pavia Trauma Management Epidemiology (PaTraME) project uses routinely collected ICD-9-CM discharge data (SDO) and the Trauma ...
Comparison of the Efficacy of Empagliflozin, Dapagliflozin, and Allopurinol Based on Serum Uric Acid Levels and Kidney Function in Patients with Type 2 Diabetes Mellitus: A Retrospective Cohort Study [0.03%]
基于血清尿酸水平和肾功能的2型糖尿病患者恩格列净、达格列净与别嘌醇疗效比较：回顾性队列研究
Roland Fejes,Tamás Jámbor,Tamás Lantos et al.
Roland Fejes et al.
Background: Type 2 diabetes mellitus (T2DM) is often associated with hyperuricemia, both conditions worsening kidney function. Sodium-glucose cotransporter 2 (SGLT2) inhibitors improve glycemic control and kidney function; however, data on ...
Comparative Study
Medical sciences (Basel, Switzerland). 2025 Dec 26;14(1):12. DOI:10.3390/medsci14010012 2025
CXCL1, RANTES, IFN-γ, and TMAO as Differential Biomarkers Associated with Cognitive Change After an Anti-Inflammatory Diet in Children with ASD and Neurotypical Peers [0.03%]
儿童抗炎饮食后ASD和普通儿童认知变化的差异性生物标志物CXCL1、RANTES、IFN-γ和TMAO的研究
Luisa Fernanda Méndez-Ramírez,Miguel Andrés Meñaca-Puentes,Luisa Matilde Salamanca-Duque et al.
Luisa Fernanda Méndez-Ramírez et al.
Background/Objective: Neuroimmune and metabolic dysregulation have been increasingly implicated in the cognitive heterogeneity of autism spectrum disorder (ASD). However, it remains unclear whether anti-inflammatory diets engage distinct bi...
AI-Driven Innovations in Transfusion Medicine: A Narrative Synthesis of Current Reviews [0.03%]
人工智能驱动的输血医学创新：当前评论的叙述综合
Daniele Giansanti,Claudia Cosenza
Daniele Giansanti
Background: Recent advancements in blood transfusion and transfusion medicine have increasingly integrated innovative technologies, including artificial intelligence (AI), machine learning, and computational intelligence. Despite numerous r...
Bacteriophages in Hip and Knee Periprosthetic Joint Infections: A Promising Tool in the Era of Antibiotic Resistance [0.03%]
噬菌体在髋关节和膝关节假体周围关节感染中的作用：抗生素耐药时代的一项有前景的技术
Filippo Migliorini,Luise Schäfer,Raju Vaishya et al.
Filippo Migliorini et al.
Background: Periprosthetic joint infections (PJIs) of the hip and knee are one of the most severe complications in arthroplasty, often requiring prolonged antibiotic therapy and multiple revision surgeries. The increasing prevalence of mult...
Lurasidone and Fluvoxamine Combination in Eating Disorders with Comorbid Obsessive-Compulsive Disorder: Preliminary Evidence from an Observational Study [0.03%]
利培酮和氟伏沙明联合治疗共病强迫症的进食障碍：一项观察性研究的初步证据
Francesco Monaco,Annarita Vignapiano,Ernesta Panarello et al.
Francesco Monaco et al.
Background: Anorexia nervosa (AN) and obsessive-compulsive disorder (OCD) share core features of cognitive rigidity, anxiety, and altered reward processing. Pharmacological options remain limited, and combined modulation ...
Observational Study
Medical sciences (Basel, Switzerland). 2025 Dec 23;14(1):8. DOI:10.3390/medsci14010008 2025
The Effect of Combined General Anesthesia and Epidural Analgesia on Postoperative Pulmonary Complications in Thoracoscopic Esophagectomy [0.03%]
联合全身麻醉和硬膜外镇痛对胸腔镜食管切除术后肺部并发症的影响
Hiroyuki Kitagawa,Keiichiro Yokota,Kento Shinnou et al.
Hiroyuki Kitagawa et al.
Background and Aims: Although combined general anesthesia and epidural analgesia are used in open surgery to promote rehabilitation and expectoration, as well as to prevent postoperative pulmonary complications, their effect in thoracoscopi...
Consequences of Hypoxic Events, Necrosis, and Microvascular Density, in Astrocytoma IDH-Mutant, CNS WHO Grade 4 [0.03%]
缺氧事件、坏死和微血管密度对IDH突变级IV星形细胞瘤的影响
Cristian Ionut Orasanu,Madalina Bosoteanu,Sorin Vamesu et al.
Cristian Ionut Orasanu et al.
Background/Objectives: Astrocytoma IDH-mutant CNS WHO grade 4 is a malignant tumor of the central nervous system characterized by tumor necrosis, microvascular proliferation, and/or homozygous CDKN2A/B deletion. This study aims to investiga...