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Seronegative Rheumatoid Arthritis: A Distinct Immunopathological Entity with Erosive Potential

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Background: Seronegative rheumatoid arthritis (SNRA), defined by the absence of rheumatoid factor (RF) and anti-citrullinated peptide antibodies (ACPA), represents 20-30% of rheumatoid arthritis cases. Once considered a milder phenotype, SNRA is now recognised... ...