Low levels of neutralizing antibodies against XBB Omicron subvariants after BA.5 infection [0.03%]
BA.5感染后对XBB奥密克戎亚变体的中和抗体水平较低
Jingyun Yang,Weiqi Hong,Hong Lei et al.
Jingyun Yang et al.
The COVID-19 response strategies in Chinese mainland were recently adjusted due to the reduced pathogenicity and enhanced infectivity of Omicron subvariants. In Chengdu, China, an infection wave was predominantly induced by the BA.5 subvari...
Lina Sun,Yanhong Su,Anjun Jiao et al.
Lina Sun et al.
T cells are crucial for immune functions to maintain health and prevent disease. T cell development occurs in a stepwise process in the thymus and mainly generates CD4+ and CD8+ T cell subsets. Upon antigen stimulation, naïve T cells diffe...
Soluble CD4 effectively prevents excessive TLR activation of resident macrophages in the onset of sepsis [0.03%]
可溶性CD4有效防止过度的TLR激活以阻止常驻巨噬细胞引发脓毒症
Sheng-Yuan Zhang,Qiu-Ping Xu,Li-Na Shi et al.
Sheng-Yuan Zhang et al.
T lymphopenia, occurring in the early phase of sepsis in response to systemic inflammation, is commonly associated with morbidity and mortality of septic infections. We have previously shown that a sufficient number of T cells is required t...
Kalliopi Pafili,Michael Roden
Kalliopi Pafili
New case of HIV cure: joined forces of haploidentical stem cells and HLA-mismatched cord blood [0.03%]
艾滋病治愈新案列：半相合干细胞联合HLA错配脐带血救治重型血液病合并艾滋病患者成功
David Peterhoff
David Peterhoff
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease [0.03%]
细胞内白蛋白预先折叠形成类囊体以维持线粒体稳态并抑制非酒精性脂肪肝病
Boyuan Ma,Anji Ju,Shaosen Zhang et al.
Boyuan Ma et al.
Hepatic mitochondrial dysfunction contributes to the progression of nonalcoholic fatty liver disease (NAFLD). However, the factors that maintain mitochondrial homeostasis, especially in hepatocytes, are largely unknown. Hepatocytes synthesi...
Neural stem cell-derived extracellular vesicles mitigate Alzheimer's disease-like phenotypes in a preclinical mouse model [0.03%]
神经干细胞衍生的细胞外囊泡可在临床前小鼠模型中缓解阿尔茨海默病样表型
Ge Gao,Congcong Li,Yizhao Ma et al.
Ge Gao et al.
A new mission for an old anti-cancer drug: harnessing hepatocyte-specific metabolic pathways against liver tumors [0.03%]
老药新使命：利用肝细胞特异性代谢途径对抗肝脏肿瘤
Weiting Liao,Diego F Calvisi,Xin Chen
Weiting Liao
Oral administration of D-glucosamine confers broad-spectrum protection against human coronaviruses including SARS-CoV-2 [0.03%]
D-葡萄糖胺口服给药对包括SARS-CoV-2在内的冠状病毒具有广谱防护作用
Qi Qi,Qi Chen,Yumei Dong et al.
Qi Qi et al.