Yanjiao Li,Jingjing Hou,Zhong Sun et al.
Yanjiao Li et al.
Neutrophil-sourced TNF in cancer: deciphering an intricate orchestrator of immunosuppressive communication in the tumor microenvironment [0.03%]
中性粒细胞来源的TNF在癌症中的作用：解析肿瘤微环境中免疫抑制通讯的一个复杂调控者
Xinyuan Zhao,Ye Lu,Li Cui
Xinyuan Zhao
Incorporation of a Toll-like receptor 2/6 agonist potentiates mRNA vaccines against cancer and infectious diseases [0.03%]
TLR2/6激动剂增强mRNA肿瘤疫苗和传染病疫苗的作用
Yangzhuo Gu,Jingyun Yang,Cai He et al.
Yangzhuo Gu et al.
mRNA vaccines have emerged rapidly in recent years as a prophylactic and therapeutic agent against various diseases including cancer and infectious diseases. Improvements of mRNA vaccines have been underway, among which boosting of efficacy...
SARS-CoV-2 spike protein receptor-binding domain perturbates intracellular calcium homeostasis and impairs pulmonary vascular endothelial cells [0.03%]
新冠病毒刺突蛋白受体结合域干扰胞内钙稳态并损害肺血管内皮细胞功能
Kai Yang,Shiyun Liu,Han Yan et al.
Kai Yang et al.
Exposure to the spike protein or receptor-binding domain (S-RBD) of SARS-CoV-2 significantly influences endothelial cells and induces pulmonary vascular endotheliopathy. In this study, angiotensin-converting enzyme 2 humanized inbred (hACE2...
A histone tale that enCOMPASSes pausing: new insights into the functional repertoire of H3K4me3 [0.03%]
H3K4me3的功能谱系：关于转录暂停的新见解
Thomas K Albert,Kornelius Kerl
Thomas K Albert
BICC1 drives pancreatic cancer progression by inducing VEGF-independent angiogenesis [0.03%]
BICC1通过诱导血管内皮生长因子非依赖性血管生成促进胰腺癌进展
Chongbiao Huang,Hui Li,Yang Xu et al.
Chongbiao Huang et al.
VEGF inhibitors are one of the most successful antiangiogenic drugs in the treatment of many solid tumors. Nevertheless, pancreatic adenocarcinoma (PAAD) cells can reinstate tumor angiogenesis via activation of VEGF-independent pathways, th...
Weifeng Zhang,Dan Xiao,Qinwen Mao et al.
Weifeng Zhang et al.
Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that inflammation is not only a result of neurodegeneration but als...
Restoring expression of Stathmin-2: a novel strategy to treat TDP-43 proteinopathies [0.03%]
通过恢复Stathmin-2的表达治疗TDP-43蛋白病的新策略
Sonja Menge,Lorena Decker,Axel Freischmidt
Sonja Menge
Targeting tumor microenvironment with antibody-guided IL-2 pro-cytokine promotes and rejuvenates dysfunctional CD8+ T cells [0.03%]
抗体引导的白细胞介素-2促细胞因子靶向肿瘤微环境可促进和恢复功能失调的CD8+t细胞
Xue Wang,Longchao Liu,Tao Yue et al.
Xue Wang et al.
Bone marrow adipoq+ cell population controls bone mass via sclerostin in mice [0.03%]
骨髓脂肪生成细胞通过硬化素调控小鼠的骨量
Huanqing Gao,Yiming Zhong,Sixiong Lin et al.
Huanqing Gao et al.