Reduced smooth muscle-fibroblasts transformation potentially decreases intestinal wound healing and colitis-associated cancer in ageing mice [0.03%]
肠道伤口愈合和炎症相关结肠癌的小鼠在老化过程中平滑肌-纤维母细胞转化减少可能会降低肠道伤口愈合和炎症相关结肠癌
Yi Liu,Yanhong Ji,Ruiyi Jiang et al.
Yi Liu et al.
Cancer and impaired tissue wound healing with ageing are closely related to the quality of life of the elderly population. Given the increased incidence of cancer and the population ageing trend globally, it is very important to explore how...
NPRC deletion mitigated atherosclerosis by inhibiting oxidative stress, inflammation and apoptosis in ApoE knockout mice [0.03%]
NPRC缺失通过抑制氧化应激、炎症和凋亡减轻载脂蛋白E基因敲除小鼠的动脉粥样硬化病理损害
Cheng Cheng,Jie Zhang,Xiaodong Li et al.
Cheng Cheng et al.
Previous studies suggested a beneficial effect of natriuretic peptides in animal models of cardiovascular disease, but the role of natriuretic peptide receptor C (NPRC) in the pathogenesis of atherosclerosis (AS) remains unknown. This study...
Predicting the next move: tracking the complexity of lung cancer evolution and metastasis [0.03%]
预测下一步：追踪肺癌演变和转移的复杂性
Carina Lorenz,Axel M Hillmer,Johannes Brägelmann
Carina Lorenz
RUNX1 promotes mitophagy and alleviates pulmonary inflammation during acute lung injury [0.03%]
RUNX1促进急性肺损伤中的线粒体自噬并缓解肺部炎症
Xiaoju Tang,Lichun Zhong,Xin Tian et al.
Xiaoju Tang et al.
Dahua Fan,Yongkai Cao,Meiqun Cao et al.
Dahua Fan et al.
Cancer remains a highly lethal disease in the world. Currently, either conventional cancer therapies or modern immunotherapies are non-tumor-targeted therapeutic approaches that cannot accurately distinguish malignant cells from healthy one...
Extracellular RNAs-TLR3 signaling contributes to cognitive impairment after chronic neuropathic pain in mice [0.03%]
外源性RNA-TLR3信号参与慢性神经痛小鼠认知障碍
Xueying Zhang,Rui Gao,Changteng Zhang et al.
Xueying Zhang et al.
Chronic pain is often associated with cognitive decline, which could influence the quality of the patient's life. Recent studies have suggested that Toll-like receptor 3 (TLR3) is crucial for memory and learning. Nonetheless, the contributi...
Calreticulin surface presentation: a signal for natural killer cells to attack [0.03%]
钙网蛋白表面表达：NK细胞攻击的信号分子
Jasmine P Castellanos,Joseph C Genereux
Jasmine P Castellanos
Commanding the Commander: structure of a key protein machinery in endosomal trafficking [0.03%]
指挥指挥官：内涵体运输中关键蛋白质机器的结构
Xin Yong,Chunzhuang Zhou,Daniel D Billadeau et al.
Xin Yong et al.
Sebaceous gland reprogramming with a single gene, PPARG, and small molecules [0.03%]
单基因和小分子重编程皮脂腺细胞
Yiqiong Liu,Shuaifei Ji,Huanhuan Gao et al.
Yiqiong Liu et al.
Tracing the failing heart: dual genetic fate mapping for target identification [0.03%]
心脏追踪：双遗传命运映射以确定靶点
Yaw Asare,Christian Stoppe,Jürgen Bernhagen
Yaw Asare