Long Chen,Mengnan Zhou,Hao Li et al.
Long Chen et al.
As key organelles involved in cellular metabolism, mitochondria frequently undergo adaptive changes in morphology, components and functions in response to various environmental stresses and cellular demands. Previous studies of mitochondria...
Cryo-EM structure of the nucleocapsid-like assembly of respiratory syncytial virus [0.03%]
呼吸道合胞病毒核壳体类似物的低温电子结构
Yan Wang,Chong Zhang,Yongbo Luo et al.
Yan Wang et al.
Respiratory syncytial virus (RSV) is a nonsegmented, negative strand RNA virus that has caused severe lower respiratory tract infections of high mortality rates in infants and the elderly, yet no effective vaccine or antiviral therapy is av...
Interaction of microglia and T cells: a deadly duo behind Tau-mediated neurodegeneration [0.03%]
小胶质细胞和T细胞的相互作用：Tau介导神经退行性疾病中的“致命组合”
Bilge Askin,Susanne Wegmann
Bilge Askin
Rough operators: sphingomyelinase inhibitors spike NK cells to kill cancer [0.03%]
粗糙型操作者：鞘氨醇肌醇酶抑制剂促使自然杀伤细胞杀死癌细胞
Mattias Carlsten,Yenan T Bryceson
Mattias Carlsten
Chemogenetic activation of G12 signaling enhances adipose tissue browning [0.03%]
化学遗传活化G12信号增强脂肪组织褐变
Yuki Ono,Ryo Ito,Kaito Arai et al.
Yuki Ono et al.
Hedgehog signaling in tissue homeostasis, cancers, and targeted therapies [0.03%]
刺猬信号在组织稳态、癌症和靶向治疗中的作用
Junjun Jing,Zhuoxuan Wu,Jiahe Wang et al.
Junjun Jing et al.
The past decade has seen significant advances in our understanding of Hedgehog (HH) signaling pathway in various biological events. HH signaling pathway exerts its biological effects through a complex signaling cascade involved with primary...
Immunotherapy in hematologic malignancies: achievements, challenges and future prospects [0.03%]
血液系统恶性肿瘤的免疫治疗：成就、挑战与未来前景
Lu Tang,Zhongpei Huang,Heng Mei et al.
Lu Tang et al.
The immune-cell origin of hematologic malignancies provides a unique avenue for the understanding of both the mechanisms of immune responsiveness and immune escape, which has accelerated the progress of immunotherapy. Several categories of ...
VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway [0.03%]
VEGF-B通过抑制FGF2/FGFR1通路防止过度血管生成
Chunsik Lee,Rongyuan Chen,Guangli Sun et al.
Chunsik Lee et al.
Although VEGF-B was discovered as a VEGF-A homolog a long time ago, the angiogenic effect of VEGF-B remains poorly understood with limited and diverse findings from different groups. Notwithstanding, drugs that inhibit VEGF-B together with ...
Carolina E Hagberg
Carolina E Hagberg