Meng Zhang,Qian Liu,Hui Meng et al.
Meng Zhang et al.
Ischemia-reperfusion (I/R) injury paradoxically occurs during reperfusion following ischemia, exacerbating the initial tissue damage. The limited understanding of the intricate mechanisms underlying I/R injury hinders the development of eff...
Josephin domain containing 2 (JOSD2) promotes lung cancer by inhibiting LKB1 (Liver kinase B1) activity [0.03%]
JOSEDO2通过抑制LKB1活性促进肺癌的发生发展中
Tao Yuan,Chenming Zeng,Jiawei Liu et al.
Tao Yuan et al.
Non-small cell lung cancer (NSCLC) ranks as one of the leading causes of cancer-related deaths worldwide. Despite the prominence and effectiveness of kinase-target therapies in NSCLC treatment, these drugs are suitable for and beneficial to...
Correction: BICC1 drives pancreatic cancer progression by inducing VEGF-independent angiogenesis [0.03%]
纠正：BICC1通过诱导非VEGF依赖的血管生成促进胰腺癌进展
Chongbiao Huang,Hui Li,Yang Xu et al.
Chongbiao Huang et al.
Published Erratum
Signal transduction and targeted therapy. 2024 Jan 5;9(1):8. DOI:10.1038/s41392-023-01721-z 2024
The role of inflammasomes in human diseases and their potential as therapeutic targets [0.03%]
炎症小体在人类疾病中的作用及其作为治疗靶点的潜力
Jing Yao,Keenan Sterling,Zhe Wang et al.
Jing Yao et al.
Inflammasomes are large protein complexes that play a major role in sensing inflammatory signals and triggering the innate immune response. Each inflammasome complex has three major components: an upstream sensor molecule that is connected ...
Correction: The Hippo signalling pathway and its implications in human health and diseases [0.03%]
修正：Hippo信号通路及其对人类健康和疾病的影响
Minyang Fu,Yuan Hu,Tianxia Lan et al.
Minyang Fu et al.
Published Erratum
Signal transduction and targeted therapy. 2024 Jan 4;9(1):5. DOI:10.1038/s41392-023-01682-3 2024
Lymphatic vessel: origin, heterogeneity, biological functions, and therapeutic targets [0.03%]
淋巴管：起源、异质性、生物功能及治疗靶点
Zhaoliang Hu,Xushi Zhao,Zhonghua Wu et al.
Zhaoliang Hu et al.
Lymphatic vessels, comprising the secondary circulatory system in human body, play a multifaceted role in maintaining homeostasis among various tissues and organs. They are tasked with a serious of responsibilities, including the regulation...
Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets [0.03%]
细胞锌代谢及锌信号传导：从生物功能到疾病和治疗靶点
Bonan Chen,Peiyao Yu,Wai Nok Chan et al.
Bonan Chen et al.
Zinc metabolism at the cellular level is critical for many biological processes in the body. A key observation is the disruption of cellular homeostasis, often coinciding with disease progression. As an essential factor in maintaining cellu...
Programmable synthetic receptors: the next-generation of cell and gene therapies [0.03%]
可编程合成受体：细胞和基因治疗的下一代技术
Fei Teng,Tongtong Cui,Li Zhou et al.
Fei Teng et al.
Cell and gene therapies hold tremendous promise for treating a range of difficult-to-treat diseases. However, concerns over the safety and efficacy require to be further addressed in order to realize their full potential. Synthetic receptor...
EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors [0.03%]
EZH2抑制剂促进年轻和成人1型糖尿病供体的β样细胞再生
Keith Al-Hasani,Safiya Naina Marikar,Harikrishnan Kaipananickal et al.
Keith Al-Hasani et al.
β-cells are a type of endocrine cell found in pancreatic islets that synthesize, store and release insulin. In type 1 diabetes (T1D), T-cells of the immune system selectively destroy the insulin-producing β-cells. Destruction of these cel...
Janus-faced Mitofusin 2 (MFN2): mitochondria-endoplasmic reticulum shaping and tethering functions unveiled [0.03%]
双面Mitofusin 2 (MFN2)：揭示线粒体-内质网的形态和连接功能
Camilla Aurora Franchino,Elisa Motori,Matteo Bergami
Camilla Aurora Franchino