Ming Yi,Tianye Li,Mengke Niu et al.
Ming Yi et al.
Cytokines are critical in regulating immune responses and cellular behavior, playing dual roles in both normal physiology and the pathology of diseases such as cancer. These molecules, including interleukins, interferons, tumor necrosis fac...
Heterogeneous hybrid immunity against Omicron variant JN.1 at 11 months following breakthrough infection [0.03%]
突破感染11个月后混合免疫对奥密克戎JN.1变异株的异质性防护作用
Xuan He,Jingyou Yu,Jiajing Jiang et al.
Xuan He et al.
In vivo evaluation of guide-free Cas9-induced safety risks in a pig model [0.03%]
体内评估无引导的Cas9诱导的安全风险猪模型中的研究
Weikai Ge,Shixue Gou,Xiaozhu Zhao et al.
Weikai Ge et al.
The CRISPR/Cas9 system has shown great potential for treating human genetic diseases through gene therapy. However, there are concerns about the safety of this system, specifically related to the use of guide-free Cas9. Previous studies hav...
G protein-mediated signal transduction: a molecular choreography of G protein activation after GTP binding [0.03%]
G蛋白介导的信号转导：GTP结合后的G蛋白激活分子事件
Evi Kostenis,Lars Jürgenliemke,Judith Alenfelder
Evi Kostenis
Hongxia Niu,Jiaying Gu,Ying Zhang
Hongxia Niu
Persisters refer to genetically drug susceptible quiescent (non-growing or slow growing) bacteria that survive in stress environments such as antibiotic exposure, acidic and starvation conditions. These cells can regrow after stress removal...
Beilei Liu,Hongyu Zhou,Licheng Tan et al.
Beilei Liu et al.
Traditional therapeutic approaches such as chemotherapy and radiation therapy have burdened cancer patients with onerous physical and psychological challenges. Encouragingly, the landscape of tumor treatment has undergone a comprehensive an...
Correction: A positive feedback inhibition of isocitrate dehydrogenase 3β on paired-box gene 6 promotes Alzheimer-like pathology [0.03%]
correction：异柠檬酸脱氢酶3β对配对盒基因6的正反馈抑制促进阿尔茨海默病样病理的发展
Xin Wang,Qian Liu,Hai-Tao Yu et al.
Xin Wang et al.
The Ca2+-sensing receptor and the pocketome: comparing nature's complexity with human intervention in receptor modulation [0.03%]
钙感应受体与结合位点组学：比较自然的复杂性与人类在受体调节中的干预作用
Edda S F Matthees,Carsten Hoffmann
Edda S F Matthees
SHR-A1811 (antibody-drug conjugate) in advanced HER2-mutant non-small cell lung cancer: a multicenter, open-label, phase 1/2 study [0.03%]
SHR-A1811（抗体药物偶联物）在HER2突变型晚期非小细胞肺癌患者中的Ib/II期临床试验
Ziming Li,Zhengbo Song,Wei Hong et al.
Ziming Li et al.
A dose-escalation and expansion, phase 1/2 study (ClinicalTrials.gov, NCT04818333) was conducted to assess the novel antibody-drug conjugate SHR-A1811 in pretreated HER2-altered advanced non-small cell lung cancer (NSCLC). Here, we report r...
Correction: MELK is an oncogenic kinase essential for metastasis, mitotic progression, and programmed death in lung carcinoma [0.03%]
关于:MELK是一种促癌激酶 对肺癌的发生发展至关重要
Qin Tang,Wan Li,Xiangjin Zheng et al.
Qin Tang et al.