Robust neutralization of SARS-CoV-2 variants including JN.1 and BA.2.87.1 by trivalent XBB vaccine-induced antibodies [0.03%]
三价XBB疫苗诱导抗体对包括JN.1和BA.2.87.1谱系在内的SARS-CoV-2变异株的广义中和作用
Xun Wang,Shujun Jiang,Wentai Ma et al.
Xun Wang et al.
Effect of plateletcrit and methylenetetrahydrofolate reductase (MTHFR) C677T genotypes on folic acid efficacy in stroke prevention [0.03%]
血小板生成素和亚甲基四氢叶酸还原酶基因多态性对卒中一级预防叶酸疗效的影响
Yuncong Shi,Zhengzhipeng Zhang,Binyan Wang et al.
Yuncong Shi et al.
Previous studies have shown that low platelet count combined with high plasma total homocysteine (tHcy) increased stroke risk and can be lowered by 73% with folic acid. However, the combined role of other platelet activation parameters and ...
Unveiling the culprit: the fusobacterium lineage that populates colorectal cancer [0.03%]
揭示元凶：结直肠癌中的弗氏菌谱系
Johannes Betge,Matthias P Ebert
Johannes Betge
A pathological joint-liver axis mediated by matrikine-activated CD4+ T cells [0.03%]
病理性的关节-肝脏轴通过基质肽激活的CD4+T细胞介导
Junzhi Yi,Hui Zhang,Fangyuan Bao et al.
Junzhi Yi et al.
The knee joint has long been considered a closed system. The pathological effects of joint diseases on distant organs have not been investigated. Herein, our clinical data showed that post-traumatic joint damage, combined with joint bleedin...
CAR-T overdrive: harnessing inosine for metabolic rewiring and stemness induction [0.03%]
CAR-T过载：利用次黄嘌呤进行代谢重构和干细胞诱导
Martí Farrera-Sal,Michael Schmueck-Henneresse
Martí Farrera-Sal
Haploidentical hematopoietic cell transplantation with or without an unrelated cord blood unit for adult acute myeloid leukemia: a multicenter, randomized, open-label, phase 3 trial [0.03%]
同基因造血细胞移植加用或不用无关脐带血对于成人急性髓系白血病的疗效：一项多中心、随机、开放标签、III期试验
Biqi Zhou,Jia Chen,Tianhui Liu et al.
Biqi Zhou et al.
Coinfusion of unrelated cord blood (UCB) units in haploidentical hematopoietic cell transplantation (haplo-HCT) (haplo-cord HCT) for hematopoietic malignancies showed promising results in previous reports, but the efficiency of haplo-cord H...
Combination therapy with oncolytic virus and T cells or mRNA vaccine amplifies antitumor effects [0.03%]
溶瘤病毒与T细胞或mRNA疫苗联合治疗可增强抗肿瘤作用
Rao Fu,Ruoyao Qi,Hualong Xiong et al.
Rao Fu et al.
Antitumor therapies based on adoptively transferred T cells or oncolytic viruses have made significant progress in recent years, but the limited efficiency of their infiltration into solid tumors makes it difficult to achieve desired antitu...
Cholangiocarcinoma combined with biliary obstruction: an exosomal circRNA signature for diagnosis and early recurrence monitoring [0.03%]
胆管癌合并胆道梗阻：用于诊断和早期复发监测的外泌体环状circRNA标志物签名
Ningyuan Wen,Dingzhong Peng,Xianze Xiong et al.
Ningyuan Wen et al.
Cholangiocarcinoma (CCA) is a highly malignant biliary tract cancer with currently suboptimal diagnostic and prognostic approaches. We present a novel system to monitor CCA using exosomal circular RNA (circRNA) via serum and biliary liquid ...
Harnessing naturally occurring mutations for T-cell therapy: a potential new avenue to enhance treatment efficacy [0.03%]
利用自然发生的突变进行T细胞治疗：提高治疗有效性的潜在新途径
Michael Hiltensperger,Jürgen Ruland,Kilian Schober
Michael Hiltensperger