Chinese expert consensus on wound repair of venous leg ulcers (2025 edition) [0.03%]
中国静脉腿部溃疡伤口愈合修复专家共识(2025版)
Pi-Hong Zhang,Xiao-Bing Fu,Yue-Sheng Huang;Wound Repair Professional Committee of Chinese Medical Doctor Association
Pi-Hong Zhang
Venous leg ulcers (VLUs) result from a multifactorial interplay of etiological factors, posing significant challenges in clinical management. Effective treatment requires a comprehensive assessment to identify the underlying pathophysiologi...
ZBP1 activated by mitochondrial damage binds to STAT3 to suppress Legumain production and exacerbate macrophage inflammation in Klebsiella pneumoniae-induced sepsis [0.03%]
由肠杆菌感染诱导的脓毒症中线粒体损伤激活的ZBP1通过与STAT3结合抑制Legumain产生并加重巨噬细胞炎症
Li-Ting Deng,Huan Yang,Xu-Fei Zhang et al.
Li-Ting Deng et al.
Background: Severe bacterial sepsis caused by Klebsiella pneumoniae (KP) is characterized by dysregulated inflammation, multiorgan injury, and high mortality, yet the key molecular drivers of this process remain incomplet...
Real-time multicenter semantic segmentation for laparoscopic gastrectomy: development, external validation and operating room deployment of an AI navigation system [0.03%]
腹腔镜胃切除术的实时多中心语义分割:AI导航系统的开发、外部验证和手术室部署
Ke-Cheng Zhang,Di Wu,Can-Rong Lu et al.
Ke-Cheng Zhang et al.
Background: Laparoscopic gastrectomy is technically demanding and errors often arise from limited situational awareness. Artificial intelligence (AI)-based computer vision may enhance intraoperative recognition of instrum...
Multicenter Study
Military Medical Research. 2026;13(1):100040. DOI:10.1016/j.mmr.2026.100040 2026
Forecasting the prevalence of epilepsy in low- and middle-income countries to 2050 using a hybrid deep neural network-transformer modeling framework: insights from the Global Burden of Disease Study 2023 [0.03%]
利用混合深度神经网络-变压器建模框架预测中低收入国家癫痫流行趋势至2050年——来自全球疾病负担研究(2023)的启示
Zhi-Jin Zhang,Hao-Feng Wang,Yu-Sha Cui et al.
Zhi-Jin Zhang et al.
Background: Epilepsy is a major public health challenge affecting individuals of all ages, especially in low- and middle-income countries (LMICs). Reliable prevalence projections are critical for healthcare planning and r...
RIMKLA promotes hypertension by activating PKM2 to trigger VSMC phenotype switch [0.03%]
RIMKLA通过激活PKM2促进高血压并触发血管平滑肌细胞表型转换
Rui Xiang,Wen-Jun Liu,Xin-Rui Zhang et al.
Rui Xiang et al.
Background: Hypertension affects around one billion adults worldwide, with abnormal glucose metabolism and vascular smooth muscle cell (VSMC) phenotype switch playing crucial roles in its pathogenesis. Pyruvate kinase M2 ...
Downregulation of FTO aggravates osteoarthritis with obesity by erasing m6A methylation of PDP2 [0.03%]
FTO下调通过擦除PDP2的m6A甲基化加重肥胖性骨关节炎
Xu-Ying Sun,Jing-Yue Su,Xin Chen et al.
Xu-Ying Sun et al.
Background: Osteoarthritis (OA) is currently the most common age-related degenerative joint disease, but there remains a lack of disease-modifying therapy for OA treatment. This study aimed to elucidate the critical roles...
From nerve to bone: a tale of autonomic nervous system, bone cells, and beyond [0.03%]
从神经到骨骼:自主神经系统、骨细胞等的故事
Wei-Jun Huang,Yong-Kang Hu,Heng-Zhen Li et al.
Wei-Jun Huang et al.
Bone is a multifunctional organ essential for structural support, protection, hematopoiesis, and endocrine regulation. Emerging research increasingly highlights the pivotal role of the nervous system in bone metabolism, repair, and musculos...
A roadmap for medical large language models: a review of foundations, applications, and challenges [0.03%]
医疗大型语言模型路线图:基础、应用与挑战综述
Yu-Yang Sha,Li Yu,Ze-Hui Lin et al.
Yu-Yang Sha et al.
Medical large language models (Med-LLMs) have shown considerable promise across a broad range of clinical tasks, including decision support, medical documentation, patient communication, multimodal analysis, and telemedicine. Their rapid de...
A translational preclinical strategy for chronic spinal cord injury: neuroprotective and regenerative potential of botulinum neurotoxin type A combined with muscle atrophy prevention via electrostimulation [0.03%]
慢性脊髓损伤的转化型临床策略:肉毒杆菌素A联合电刺激预防肌肉萎缩在神经保护和再生中的潜力
Valentina Mastrorilli,Siro Luvisetto,Veronica Ruggieri et al.
Valentina Mastrorilli et al.
Background: Spinal cord injury (SCI) triggers persistent neuroinflammation, gliosis, neuronal loss, and demyelination, leading to motor deficits and neuropathic pain (NeP). Botulinum neurotoxin type A (BoNT/A) has shown a...