Effectiveness and cost-effectiveness of risk-adapted colorectal cancer screening: a randomized controlled trial and modeling analysis [0.03%]
基于风险的大肠癌筛查的效果及成本效益分析：一项随机对照试验和建模分析
Hong-Da Chen,Bin Lu,Ju-Fang Shi et al.
Hong-Da Chen et al.
Background: Risk-adapted colorectal cancer (CRC) screening has the potential to balance effectiveness with resource demands, yet evidence comparing it with established methods remains limited. This study aims to compare o...
Randomized Controlled Trial
Military Medical Research. 2025 Nov 24;12(1):82. DOI:10.1186/s40779-025-00671-7 2025
Challenges, opportunities, and future perspectives of portable field endoscopy [0.03%]
便携式内镜的挑战、机遇和未来展望
Ke He,Shu-Yi Wang,Jun Ren
Ke He
The emerging role of ferroptosis in the pathological development and progression of sepsis [0.03%]
铁死亡在脓毒症病理发生发展中的作用不容忽视
Hui-Ting Zhou,Jie Huang,Ya-Kun Liu et al.
Hui-Ting Zhou et al.
Ferroptosis, a form of iron-dependent regulated cell death (RCD), is emerging as a critical mechanism in the pathogenesis and progression of sepsis. This review highlights the intricate molecular pathways and hallmark features of ferroptosi...
Diverging global incidence trends of early-onset cancers: comparisons with incidence trends of later-onset cancers and mortality trends of early-onset cancers [0.03%]
早发性癌症全球发病趋势差异：与晚发性癌症发病率和早发性癌症死亡率趋势比较
Miyu Terashima,Kota Nakayama,Sora Shirai et al.
Miyu Terashima et al.
Background: The global increase in the incidence of early-onset cancers (defined as cancers diagnosed at 20-49 years old) is a serious public health problem. We investigated 1) whether the incidence trend of early-onset c...
TNC-targeted CAR-macrophage therapy alleviates liver fibrosis in mice [0.03%]
靶向T细胞受体的CAR-巨噬细胞疗法可缓解小鼠肝纤维化
Kai-Zhao Chen,Zi-Yang Lin,Long-Jun Chen et al.
Kai-Zhao Chen et al.
Background: Tenascin-C (TNC) is an extracellular matrix (ECM) protein involved in tissue damage and fibrosis. Chimeric antigen receptor (CAR) cell therapy is a novel therapeutic approach that has attracted increasing atte...
Heng Zhang,Wen-Jin Chen,Yan-Gong Chao et al.
Heng Zhang et al.
Systemic complications are common after acute brain injury (ABI) and may trigger coagulation cascades, systemic inflammation, as well as dysfunction of the cardiovascular, respiratory, and gastrointestinal systems, etc. The pathogenesis of ...
Jing-Ben Zheng,Xiao-Ye Li,Ji-Min Zhu et al.
Jing-Ben Zheng et al.
Immunotherapy for cardiovascular diseases (CVDs) holds great promise for precision management by modulating localized immune-inflammatory responses. The interplay between focal cardiovascular pathology and panvascular disease, necessitates ...
Integrating artificial intelligence with human reasoning in oncology: questions on real-world implementation and patient-centric evidence [0.03%]
肿瘤学中将人工智能与人类推理相结合：关于实际应用和以患者为中心的证据的问题
Carlos M Ardila,Anny Marcela Vivares-Builes,Eliana Pineda-Vélez
Carlos M Ardila
Chinese expert consensus on prevention, diagnosis, and management of venous thromboembolism in adult burn patients (2024) [0.03%]
中国成年烧伤患者静脉血栓栓塞症防治管理专家共识（2024）
Feng Zhu,Xiao-Bin Liu,Wei Zhou et al.
Feng Zhu et al.
Venous thromboembolism (VTE) management in adult burn patients has become a crucial focus in China. The intricate nature of VTE necessitates specialized anticoagulation strategies due to the unique challenges posed by burn injuries. To addr...
Ex-vivo limb perfusion in military and civilian medicine: inspired by ex-vivo organ perfusion, pioneered for traumatic limb amputation and peripheral nerve regeneration [0.03%]
体外肢体灌注在军事医学和民用医学中的应用：由体外器官灌注启发，旨在治疗创伤性截肢和周围神经再生
Kirsten Haastert-Talini,Katherina Katsirntaki,Svenja Kankowski et al.
Kirsten Haastert-Talini et al.
Background: Traumatic amputations have increased worldwide over the past two decades and are expected to increase by 72% by 2050. Surgical replantation provides superior functional recovery and patient satisfaction but is...