Jennifer March,Sebastian Gluth
Jennifer March
Hunger is a biological drive which can promote unhealthy dietary decisions. Yet, the cognitive mechanisms underlying this effect, and in particular the interactive role of attention and choice processes, remain elusive. To address this gap,...
Inference technique for the synaptic conductances in rhythmically active networks and application to respiratory central pattern generation circuits [0.03%]
节律性活性网络中突触电导的推断方法及其在呼吸中枢模式生成回路中的应用
Yaroslav Molkov,Anke Borgmann,Hidehiko Koizumi et al.
Yaroslav Molkov et al.
Unraveling synaptic interactions between excitatory and inhibitory interneurons within rhythmic neural circuits, such as central pattern generation (CPG) circuits for rhythmic motor behaviors, is critical for deciphering circuit interaction...
Human eIF2A has a minimal role in translation initiation and in uORF-mediated translational control in HeLa cells [0.03%]
人源eIF2A在体外和HeLa细胞中对翻译起始及uORF介导的翻译调控作用有限
Mykola Roiuk,Marilena Neff,Aurelio A Teleman
Mykola Roiuk
Translation initiation in eukaryotes requires a 40 S ribosome loaded with initiator tRNA which scans for an initiation codon. The initiator tRNA is usually recruited to the ribosome as part of a ternary complex composed of initiator tRNA, e...
Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution [0.03%]
刺胞动物胚胎的平面细胞极性协调为动物体轴进化提供线索
Julie Uveira,Antoine Donati,Marvin Léria et al.
Julie Uveira et al.
Body axis specification is a crucial event in animal embryogenesis and was an essential evolutionary innovation for founding the animal kingdom. This process involves two distinct components that coordinate to establish the spatial organisa...
Exploiting functional regions in the viral RNA genome as druggable entities [0.03%]
开发病毒RNA基因组的功能区域作为可成药实体
Dehua Luo,Yingge Zheng,Zhiyuan Huang et al.
Dehua Luo et al.
RNA-targeting compounds or small interfering RNAs (siRNAs) offer a potent means to control viral infections. An essential prerequisite for their design depends on identifying conserved and functional viral RNA structures in cells. Technique...
Lana Heganovic,Luiz F M Passalacqua
Lana Heganovic
A strategy that analyzes the structural properties of RNA could help identify regions that are promising targets for antiviral drugs. ...
Editorial
eLife. 2025 Jul 2:14:e107757. DOI:10.7554/eLife.107757 2025
Cardiac fibroblasts regulate myocardium and coronary vasculature development in the murine heart via the collagen signaling pathway [0.03%]
心脏成纤维细胞通过胶原信号通路调控小鼠心脏心肌和冠状血管发育
Yiting Deng,Yuanhang He,Juan Xu et al.
Yiting Deng et al.
The fibroblast (FB), cardiomyocyte (CM), and vascular endothelial cell (Vas_EC) are the three major cell types in the heart, yet their relationships during development are largely unexplored. To address this gap, we employed RNA staining of...
Gabriela Krejčová,Adam Bajgar
Gabriela Krejčová
Traditionally, insects have been thought to be entirely dependent on their innate immune system, which has little capacity for the acquisition of experience from previous infections. However, much experimental evidence has challenged this v...
A neuromorphic model of active vision shows how spatiotemporal encoding in lobula neurons can aid pattern recognition in bees [0.03%]
一种神经形态模型展示了活动视觉如何在切叶工蜂中编码时空以帮助图案识别
HaDi MaBouDi,Mark Roper,Marie-Geneviève Guiraud et al.
HaDi MaBouDi et al.
Bees' remarkable visual learning abilities make them ideal for studying active information acquisition and representation. Here, we develop a biologically inspired model to examine how flight behaviours during visual scanning shape neural r...
Effects of experiencing the COVID-19 pandemic on optimistically biased belief updating [0.03%]
经历COVID-19大流行对乐观偏见信念更新的影响
Iraj Khalid,Orphee Morlaas,Hugo Bottemanne et al.
Iraj Khalid et al.
Optimistically biased belief updating is essential for mental health and resilience in adversity. Here, we asked how experiencing the COVID-19 pandemic affected optimism biases in updating beliefs about the future. One hundred and twenty-th...