The functional significance of dentin sialoprotein-phosphophoryn and dentin sialoprotein [0.03%]
关于牙本质糖蛋白和牙本质涎蛋白的功能意义
Helena Ritchie
Helena Ritchie
Phosphophoryn (PP) and dentin sialoprotein (DSP) are the most dominant non-collagenous proteins in dentin. PP is an extremely acidic protein that can function as a mineral nucleator for dentin mineralization. DSP was first identified in 198...
ERK phosphorylation functions in invadopodia formation in tongue cancer cells in a novel silicate fibre-based 3D cell culture system [0.03%]
新的硅酸盐纤维基三维细胞培养系统中ERK磷酸化在舌癌细胞侵袭小体形成中的作用研究
Masaharu Noi,Ken-Ichi Mukaisho,Saori Yoshida et al.
Masaharu Noi et al.
To screen for additional treatment targets against tongue cancer, we evaluated the contributions of extracellular signal-related kinase (ERK), AKT and ezrin in cancer development. Immunohistochemical staining showed that ERK and ezrin expre...
TGF-β2 downregulates osteogenesis under inflammatory conditions in dental follicle stem cells [0.03%]
TGF-β2在炎症条件下通过抑制牙囊干细胞成骨分化的作用
Soyoun Um,Joo-Hee Lee,Byoung-Moo Seo
Soyoun Um
Bone formation is important for the reconstruction of bone-related structures in areas that have been damaged by inflammation. Inflammatory conditions such as those that occur in patients with rheumatoid arthritis, cystic fibrosis, and peri...
Whole exome sequencing identifies an AMBN missense mutation causing severe autosomal-dominant amelogenesis imperfecta and dentin disorders [0.03%]
全外显子组测序鉴定到一个导致严重常染色体显性遗传的牙本质和牙釉质发育不全的AMBN错义突变
Ting Lu,Meiyi Li,Xiangmin Xu et al.
Ting Lu et al.
Tooth development is a complex process that involves precise and time-dependent orchestration of multiple genetic, molecular, and cellular interactions. Ameloblastin (AMBN, also named "amelin" or "sheathlin") is the second most abundant ena...
Selective serotonin re-uptake inhibitor sertraline inhibits bone healing in a calvarial defect model [0.03%]
选择性5-羟色胺再摄取抑制剂盐酸舍曲林通过抑制颅骨缺损处成骨而延缓骨折愈合
R Nicole Howie,Samuel Herberg,Emily Durham et al.
R Nicole Howie et al.
Bone wound healing is a highly dynamic and precisely controlled process through which damaged bone undergoes repair and complete regeneration. External factors can alter this process, leading to delayed or failed bone wound healing. The fin...
Transcriptional activation of glucose transporter 1 in orthodontic tooth movement-associated mechanical response [0.03%]
正畸牙齿移动相关机械反应中的葡萄糖转运蛋白1的转录激活
Yu Wang,Qian Li,Fuliang Liu et al.
Yu Wang et al.
The interplay between mechanoresponses and a broad range of fundamental biological processes, such as cell cycle progression, growth and differentiation, has been extensively investigated. However, metabolic regulation in mechanobiology rem...
Xin Xu,Feng Chen,Zhengwei Huang et al.
Xin Xu et al.
The "Biofilms, Microbiomes and Oral Diseases: Challenges and Future Perspectives" symposium jointly organized by Penn Dental Medicine and West China School of Stomatology was held on 30 September 2017 at Penn Wharton China Center (PWCC) in ...
Xianghong Luan,Xiaofeng Zhou,Afsar Naqvi et al.
Xianghong Luan et al.
MicroRNAs (miRNAs) are critical regulators of the host immune and inflammatory response against bacterial pathogens. In the present review, we discuss target genes, target gene functions, the potential regulatory role of miRNAs in periodont...
Streptococcus mutans activates the AIM2, NLRP3 and NLRC4 inflammasomes in human THP-1 macrophages [0.03%]
变异链球菌激活人单核细胞THP-1的AIM2，NLRP3和NLRC4炎性小体
Yuri Song,Hee Sam Na,Eunjoo Park et al.
Yuri Song et al.
Streptococcus mutans (S. mutans), a major aetiologic agent of dental caries, is involved in systemic diseases, such as bacterial endocarditis, if it enters the bloodstream through temporary bacteraemia. Interleukin (IL)-1β, a proinflammato...
Effect of low-level laser therapy on tooth-related pain and somatosensory function evoked by orthodontic treatment [0.03%]
低水平激光治疗对正畸治疗引起的牙痛和体感功能的影响
Song Wu,Yinan Chen,Jinglu Zhang et al.
Song Wu et al.
Low-level laser therapy (LLLT) may have an effect on the pain associated with orthodontic treatment. The aim of this study was to evaluate the effect of LLLT on pain and somatosensory sensitization induced by orthodontic treatment. Forty in...
Randomized Controlled Trial
International journal of oral science. 2018 Jul 2;10(3):22. DOI:10.1038/s41368-018-0023-0 2018