Selective serotonin re-uptake inhibitor sertraline inhibits bone healing in a calvarial defect model [0.03%]
选择性5-羟色胺再摄取抑制剂盐酸舍曲林通过抑制颅骨缺损处成骨而延缓骨折愈合
R Nicole Howie,Samuel Herberg,Emily Durham et al.
R Nicole Howie et al.
Bone wound healing is a highly dynamic and precisely controlled process through which damaged bone undergoes repair and complete regeneration. External factors can alter this process, leading to delayed or failed bone wound healing. The fin...
Transcriptional activation of glucose transporter 1 in orthodontic tooth movement-associated mechanical response [0.03%]
正畸牙齿移动相关机械反应中的葡萄糖转运蛋白1的转录激活
Yu Wang,Qian Li,Fuliang Liu et al.
Yu Wang et al.
The interplay between mechanoresponses and a broad range of fundamental biological processes, such as cell cycle progression, growth and differentiation, has been extensively investigated. However, metabolic regulation in mechanobiology rem...
Xin Xu,Feng Chen,Zhengwei Huang et al.
Xin Xu et al.
The "Biofilms, Microbiomes and Oral Diseases: Challenges and Future Perspectives" symposium jointly organized by Penn Dental Medicine and West China School of Stomatology was held on 30 September 2017 at Penn Wharton China Center (PWCC) in ...
Xianghong Luan,Xiaofeng Zhou,Afsar Naqvi et al.
Xianghong Luan et al.
MicroRNAs (miRNAs) are critical regulators of the host immune and inflammatory response against bacterial pathogens. In the present review, we discuss target genes, target gene functions, the potential regulatory role of miRNAs in periodont...
Streptococcus mutans activates the AIM2, NLRP3 and NLRC4 inflammasomes in human THP-1 macrophages [0.03%]
变异链球菌激活人单核细胞THP-1的AIM2，NLRP3和NLRC4炎性小体
Yuri Song,Hee Sam Na,Eunjoo Park et al.
Yuri Song et al.
Streptococcus mutans (S. mutans), a major aetiologic agent of dental caries, is involved in systemic diseases, such as bacterial endocarditis, if it enters the bloodstream through temporary bacteraemia. Interleukin (IL)-1β, a proinflammato...
Effect of low-level laser therapy on tooth-related pain and somatosensory function evoked by orthodontic treatment [0.03%]
低水平激光治疗对正畸治疗引起的牙痛和体感功能的影响
Song Wu,Yinan Chen,Jinglu Zhang et al.
Song Wu et al.
Low-level laser therapy (LLLT) may have an effect on the pain associated with orthodontic treatment. The aim of this study was to evaluate the effect of LLLT on pain and somatosensory sensitization induced by orthodontic treatment. Forty in...
Randomized Controlled Trial
International journal of oral science. 2018 Jul 2;10(3):22. DOI:10.1038/s41368-018-0023-0 2018
Epithelial cell adhesion efficacy of a novel peptide identified by panning on a smooth titanium surface [0.03%]
一种新型肽在光滑钛表面黏附上皮细胞有效性的筛选与鉴定
Hidemichi Kihara,David M Kim,Masazumi Nagai et al.
Hidemichi Kihara et al.
Epithelial attachment via the basal lamina on the tooth surface provides an important structural defence mechanism against bacterial invasion in combating periodontal disease. However, when considering dental implants, strong epithelial att...
Effects of water-aging for 6 months on the durability of a novel antimicrobial and protein-repellent dental bonding agent [0.03%]
一种新型抗菌和防蛋白粘结剂材料的耐水性研究(老化六个月)
Ning Zhang,Ke Zhang,Michael D Weir et al.
Ning Zhang et al.
Biofilms at the tooth-restoration bonded interface can produce acids and cause recurrent caries. Recurrent caries is a primary reason for restoration failures. The objectives of this study were to synthesize a novel bioactive dental bonding...
Local icariin application enhanced periodontal tissue regeneration and relieved local inflammation in a minipig model of periodontitis [0.03%]
局部给予岩白菜素能增强牙周组织再生并缓解实验性猪牙周炎模型的局部炎症反应
Xiuli Zhang,Nannan Han,Guoqing Li et al.
Xiuli Zhang et al.
Periodontitis is an inflammatory autoimmune disease. Treatment should alleviate inflammation, regulate the immune reaction and promote periodontal tissue regeneration. Icariin is the main active ingredient of Epimedii Folium, and it is a pr...
Bone-conditioned medium contributes to initiation and progression of osteogenesis by exhibiting synergistic TGF-β1/BMP-2 activity [0.03%]
骨诱导介质通过协同分泌TGF-β1/BMP-2促进成骨发生及进展
Maria B Asparuhova,Jordi Caballé-Serrano,Daniel Buser et al.
Maria B Asparuhova et al.
Guided bone regeneration (GBR) often utilizes a combination of autologous bone grafts, deproteinized bovine bone mineral (DBBM), and collagen membranes. DBBM and collagen membranes pre-coated with bone-conditioned medium (BCM) extracted fro...