Disturbed bone remodelling activity varies in different stages of experimental, gradually progressive apical periodontitis in rats [0.03%]
实验性根尖周炎不同阶段受累牙骨改建活动的改变
Ruoshi Xu,Daimo Guo,Xuedong Zhou et al.
Ruoshi Xu et al.
Bone remodelling keeps going through the lifespan of human by bone formation and bone resorption. In the craniofacial region, mandibles act as the main force for biting and chewing, and also become susceptible to a common bone-loss disease,...
Divide and conquer: two stem cell populations in squamous epithelia, reserves and the active duty forces [0.03%]
分化与占领：鳞状上皮中的两种干细胞群，储备部队和现役部队
Spencer Dunaway,Alexandra Rothaus,Yuhang Zhang et al.
Spencer Dunaway et al.
Stem cells are of great interest to the scientific community due to their potential role in regenerative and rejuvenative medicine. However, their role in the aging process and carcinogenesis remains unclear. Because DNA replication in stem...
Stem cell-based bone and dental regeneration: a view of microenvironmental modulation [0.03%]
基于干细胞的骨和牙再生：微环境调控视角
Chenxi Zheng,Ji Chen,Shiyu Liu et al.
Chenxi Zheng et al.
In modern medicine, bone and dental loss and defects are common and widespread morbidities, for which regenerative therapy has shown great promise. Mesenchymal stem cells, obtained from various sources and playing an essential role in organ...
Conservative and functional surgery in the treatment of salivary gland tumours [0.03%]
保守性功能外科手术在治疗唾液腺肿瘤中的应用
Guangyan Yu,Xin Peng
Guangyan Yu
The principle of modern oncological surgery is to conserve the functional organs or tissues as much as possible based on eradication of the tumour. For salivary gland tumours, conservative and functional salivary surgery, including partial ...
Salivary mycobiome dysbiosis and its potential impact on bacteriome shifts and host immunity in oral lichen planus [0.03%]
口腔扁平苔藓中口咽真菌微生态失调及其对细菌微生态和宿主免疫的影响研究
Yan Li,Kun Wang,Bo Zhang et al.
Yan Li et al.
The biodiversity of the mycobiome, an important component of the oral microbial community, and the roles of fungal-bacterial and fungal-immune system interactions in the pathogenesis of oral lichen planus (OLP) remain largely uncharacterize...
Periodontitis-induced systemic inflammation exacerbates atherosclerosis partly via endothelial-mesenchymal transition in mice [0.03%]
牙周炎通过诱导全身炎症加速小鼠动脉粥样硬化形成血管内皮-间充质转化所致
Jin Sook Suh,Sol Kim,Kristina I Boström et al.
Jin Sook Suh et al.
Growing evidence suggests close associations between periodontitis and atherosclerosis. To further understand the pathological relationships of these associations, we developed periodontitis with ligature placement around maxillary molars o...
Harnessing the HDAC-histone deacetylase enzymes, inhibitors and how these can be utilised in tissue engineering [0.03%]
组蛋白去乙酰化酶（HDAC）酶、抑制剂及其在组织工程中的应用潜力
Liam Lawlor,Xuebin B Yang
Liam Lawlor
There are large knowledge gaps regarding how to control stem cells growth and differentiation. The limitations of currently available technologies, such as growth factors and/or gene therapies has led to the search of alternatives. We explo...
Compliant substratum modulates vinculin expression in focal adhesion plaques in skeletal cells [0.03%]
顺应性底物调节骨骼细胞焦粘附斑中的vinculin表达
Chenchen Zhou,Qingxuan Wang,Demao Zhang et al.
Chenchen Zhou et al.
The biophysical properties of the extracellular matrix (ECM) dictate tissue-specific cell behaviour. In the skeleton system, bone shows the potential to adapt its architecture and contexture to environmental rigidity via the bone remodellin...
Human genes influence the interaction between Streptococcus mutans and host caries susceptibility: a genome-wide association study in children with primary dentition [0.03%]
人类基因影响牙菌斑致龋细菌与宿主的相互作用：儿童乳牙期的全基因组关联研究
Ying Meng,Tongtong Wu,Ronald Billings et al.
Ying Meng et al.
Streptococcus mutans is a well-known cause of dental caries, due to its acidogenicity, aciduricity, and ability to synthesize exopolysaccharides in dental plaques. Intriguingly, not all children who carry S. mutans manifest caries, even wit...
Recent advances in cell sheet technology for bone and cartilage regeneration: from preparation to application [0.03%]
细胞片在骨和软骨再生领域的研究进展：从制备到应用
Yuezhi Lu,Wenjie Zhang,Jie Wang et al.
Yuezhi Lu et al.
Bone defects caused by trauma, tumour resection, infection and congenital deformities, together with articular cartilage defects and cartilage-subchondral bone complex defects caused by trauma and degenerative diseases, remain great challen...