VPS4B mutation impairs the osteogenic differentiation of dental follicle cells derived from a patient with dentin dysplasia type I [0.03%]
I型牙本质发育不全患者齿囊细胞的成骨分化受到VPS4B基因突变的影响
Qiang Li,Fangli Lu,Tianxuan Chen et al.
Qiang Li et al.
A splicing mutation in VPS4B can cause dentin dysplasia type I (DD-I), a hereditary autosomal-dominant disorder characterized by rootless teeth, the etiology of which is genetically heterogeneous. In our study, dental follicle cells (DFCs) ...
Computational technology for nasal cartilage-related clinical research and application [0.03%]
鼻软骨临床研究与应用的计算技术
Bing Shi,Hanyao Huang
Bing Shi
Surgeons need to understand the effects of the nasal cartilage on facial morphology, the function of both soft tissues and hard tissues and nasal function when performing nasal surgery. In nasal cartilage-related surgery, the main goals for...
Qingyue Xiao,Yuning Zhang,Xingying Qi et al.
Qingyue Xiao et al.
As a member of the AFF (AF4/FMR2) family, AFF4 is a transcription elongation factor that is a component of the super elongation complex. AFF4 serves as a scaffolding protein that connects transcription factors and promotes gene transcriptio...
Radiotherapy targeting cancer stem cells "awakens" them to induce tumour relapse and metastasis in oral cancer [0.03%]
放射治疗通过唤醒癌症干细胞来诱导口腔癌的肿瘤复发和转移
Yangfan Liu,Miao Yang,Jingjing Luo et al.
Yangfan Liu et al.
Radiotherapy is one of the most common treatments for oral cancer. However, in the clinic, recurrence and metastasis of oral cancer occur after radiotherapy, and the underlying mechanism remains unclear. Cancer stem cells (CSCs), considered...
Berberine mediates root remodeling in an immature tooth with apical periodontitis by regulating stem cells from apical papilla differentiation [0.03%]
小檗碱通过调节根尖乳头干细胞分化介导牙根重塑以治疗非化脓性根尖周炎的作用及机制研究
Yujia Cui,Jing Xie,Yujie Fu et al.
Yujia Cui et al.
Once pulp necrosis or apical periodontitis occurs on immature teeth, the weak root and open root apex are challenging to clinicians. Berberine (BBR) is a potential medicine for bone disorders, therefore, we proposed to apply BBR in root can...
Gap junction-mediated cell-to-cell communication in oral development and oral diseases: a concise review of research progress [0.03%]
牙间隙连接介导的细胞间通讯与口腔发育及疾病研究进展的小结
Wenjing Liu,Yujia Cui,Jieya Wei et al.
Wenjing Liu et al.
Homoeostasis depends on the close connection and intimate molecular exchange between extracellular, intracellular and intercellular networks. Intercellular communication is largely mediated by gap junctions (GJs), a type of specialized memb...
Immune checkpoint pathways in immunotherapy for head and neck squamous cell carcinoma [0.03%]
免疫检查点途径在头颈部鳞状细胞癌免疫治疗中的作用
Zi Mei,Junwen Huang,Bin Qiao et al.
Zi Mei et al.
With the understanding of the complex interaction between the tumour microenvironment and immunotherapy, there is increasing interest in the role of immune regulators in the treatment of head and neck squamous cell carcinoma (HNSCC). Activa...
Characteristics of oral methicillin-resistant Staphylococcus epidermidis isolated from dental plaque [0.03%]
来自牙菌斑的耐甲氧西林表皮葡萄球菌的特征
Boyu Tang,Tao Gong,Yujia Cui et al.
Boyu Tang et al.
The oral microbial community is widely regarded as a latent reservoir of antibiotic resistance genes. This study assessed the molecular epidemiology, susceptibility profile, and resistance mechanisms of 35 methicillin-resistant Staphylococc...
LncRNA Nron regulates osteoclastogenesis during orthodontic bone resorption [0.03%]
长链非编码RNA Nron在正畸骨吸收过程中的破骨细胞生成调控作用
Ruilin Zhang,Junhui Li,Gongchen Li et al.
Ruilin Zhang et al.
Activation of osteoclasts during orthodontic tooth treatment is a prerequisite for alveolar bone resorption and tooth movement. However, the key regulatory molecules involved in osteoclastogenesis during this process remain unclear. Long no...
Human β-defensin 3 gene modification promotes the osteogenic differentiation of human periodontal ligament cells and bone repair in periodontitis [0.03%]
人β-防御素3基因修饰促进牙周韧带细胞的成骨分化及牙周炎骨缺损再生修复
Lingjun Li,Han Jiang,Rixin Chen et al.
Lingjun Li et al.
Efforts to control inflammation and achieve better tissue repair in the treatment of periodontitis have been ongoing for years. Human β-defensin 3, a broad-spectrum antimicrobial peptide has been proven to have a variety of biological func...