Interleukin-1β is a potential therapeutic target for periodontitis: a narrative review [0.03%]
白细胞介素-1β可能是牙周炎的潜在治疗靶点：综述性文章
Ran Cheng,Zhiwu Wu,Mingming Li et al.
Ran Cheng et al.
Interleukin(IL)-1β, a pro-inflammatory cytokine, was elevated and participates in periodontitis. Not only the link between IL-1β and periodontitis was proved by clinical evidence, but also the increased IL-1β triggers a series of inflamm...
IKKβ overexpression together with a lack of tumour suppressor genes causes ameloblastic odontomas in mice [0.03%]
IKKβ过表达联合抑癌基因缺失可导致小鼠成釉细胞牙瘤形成
Angustias Page,Ana Bravo,Cristian Suarez-Cabrera et al.
Angustias Page et al.
Odontogenic tumours are a heterogeneous group of lesions that develop in the oral cavity region and are characterized by the formation of tumoural structures that differentiate as teeth. Due to the diversity of their histopathological chara...
The role of mechanotransduction versus hypoxia during simulated orthodontic compressive strain-an in vitro study of human periodontal ligament fibroblasts [0.03%]
体外研究：牙周韧带纤维细胞在正畸模拟压缩应变期间机激转导与低氧的作用关系
Niklas Ullrich,Agnes Schröder,Jonathan Jantsch et al.
Niklas Ullrich et al.
During orthodontic tooth movement (OTM) mechanical forces trigger pseudo-inflammatory, osteoclastogenic and remodelling processes in the periodontal ligament (PDL) that are mediated by PDL fibroblasts via the expression of various signallin...
The cytokine network involved in the host immune response to periodontitis [0.03%]
宿主免疫反应在牙周炎中的细胞因子网络涉及免疫反应
Weiyi Pan,Qingxuan Wang,Qianming Chen
Weiyi Pan
Periodontitis is an inflammatory disease involving the destruction of both soft and hard tissue in the periodontal region. Although dysbiosis of the local microbial community initiates local inflammation, over-activation of the host immune ...
β-Arrestin 1 (ARRB1) serves as a molecular marker of the peripheral circadian rhythm [0.03%]
β- arrestin 1 (ARRB1)可作为外周生物钟分子标志物
Tatsunosuke Tomita,Taisuke Mori,Yoshiaki Onishi
Tatsunosuke Tomita
The control of the circadian rhythm is important for health because it regulates physiological functions and is associated with health hazards. We aimed to identify a circadian biomarker of health status in human saliva, since collecting sa...
Filamentation initiated by Cas2 and its association with the acquisition process in cells [0.03%]
Cas2诱导的细丝形成及其与获得过程的关联性研究
Lei Wang,Xin Yu,Mengjie Li et al.
Lei Wang et al.
Cas1-and-Cas2-mediated new spacer acquisition is an essential process for bacterial adaptive immunity. The process is critical for the ecology of the oral microflora and oral health. Although molecular mechanisms for spacer acquisition are ...
Minimal invasive microscopic tooth preparation in esthetic restoration: a specialist consensus [0.03%]
微侵袭显微根面预备在美观修复中的应用专家共识
Haiyang Yu,Yuwei Zhao,Junying Li et al.
Haiyang Yu et al.
By removing a part of the structure, the tooth preparation provides restorative space, bonding surface, and finish line for various restorations on abutment. Preparation technique plays critical role in achieving the optimal result of tooth...
Advancing antimicrobial strategies for managing oral biofilm infections [0.03%]
抗菌策略的进展在管理口腔生物膜感染中的应用
Yang Jiao,Franklin R Tay,Li-Na Niu et al.
Yang Jiao et al.
Effective control of oral biofilm infectious diseases represents a major global challenge. Microorganisms in biofilms exhibit increased drug tolerance compared with planktonic cells. The present review covers innovative antimicrobial strate...
Activation of mitogen-activated protein kinases in satellite glial cells of the trigeminal ganglion contributes to substance P-mediated inflammatory pain [0.03%]
三叉神经节卫星胶质细胞活化的MAPK信号通路参与SP介导的炎性痛调节作用
Yanyan Zhang,Ning Song,Fei Liu et al.
Yanyan Zhang et al.
Inflammatory orofacial pain, in which substance P (SP) plays an important role, is closely related to the cross-talk between trigeminal ganglion (TG) neurons and satellite glial cells (SGCs). SGC activation is emerging as the key mechanism ...
3D cellular visualization of intact mouse tooth using optical clearing without decalcification [0.03%]
无需脱钙的光学透明化技术对完整鼠牙进行三维细胞水平视觉成像研究
Sujung Hong,Jingu Lee,Jin Man Kim et al.
Sujung Hong et al.
Dental pulp is composed of nerves, blood vessels, and various types of cells and surrounded by a thick and hard enamel-dentin matrix. Due to its importance in the maintenance of tooth vitality, there have been intensive efforts to analyze t...