Pathogenesis and multidisciplinary management of medication-related osteonecrosis of the jaw [0.03%]
药物相关性颌骨坏死的发病机理和多学科处理方法
Lina He,Xiangyu Sun,Zhijie Liu et al.
Lina He et al.
Medication-related osteonecrosis of the jaw (MRONJ) is a serious side effect of bone-modifying agents and inhibits angiogenesis agents. Although the pathogenesis of MRONJ is not entirely clear, multiple factors may be involved in specific m...
Evaluation of four final irrigation protocols for cleaning root canal walls [0.03%]
四种根管冲洗方案的评估及其对根管壁清洁效果的影响
Qiang Li,Qian Zhang,Xiaoying Zou et al.
Qiang Li et al.
The aim of this study was to compare the efficiency of four final irrigation protocols in smear layer removal and bacterial inhibition in root canal systems. Thirty roots inoculated with Enterococcus faecalis were prepared with ProTaper Uni...
Porphyromonas gingivalis disrupts vascular endothelial homeostasis in a TLR-NF-κB axis dependent manner [0.03%]
Porphyromonas gingivalis 通过TLR-NF-κB轴依赖性方式破坏血管内皮的稳态
Mengru Xie,Qingming Tang,Shaoling Yu et al.
Mengru Xie et al.
Cardiovascular disease is still the leading cause of mortality worldwide. Vascular endothelial dysfunction is viewed as the initial step of most cardiovascular diseases. Many studies have indicated that periodontal pathogens, especially Por...
Two-in-one strategy: a remineralizing and anti-adhesive coating against demineralized enamel [0.03%]
双效策略：针对脱矿牙釉质的再矿化和抗黏附涂层
Ailin Hou,Jun Luo,Min Zhang et al.
Ailin Hou et al.
Tooth enamel is prone to be attacked by injurious factors, leading to a de/remineralization imbalance. To repair demineralized enamel and prevent pulp inflammation caused by biofilm accumulation, measures are needed to promote remineralizat...
Nociceptive behavioural assessments in mouse models of temporomandibular joint disorders [0.03%]
鼠标颞下颌关节障碍的痛觉行为评估
Jun Li,Kaige Ma,Dan Yi et al.
Jun Li et al.
Orofacial pain or tenderness is a primary symptom associated with temporomandibular joint (TMJ) disorders (TMDs). To understand the pathological mechanisms underlying TMDs, several mouse models have been developed, including mechanical stim...
Quaternary ammonium-induced multidrug tolerant Streptococcus mutans persisters elevate cariogenic virulence in vitro [0.03%]
季铵盐诱导的多重耐药性链球菌变异株体外提高龋齿致病性
Ya-Ling Jiang,Wei Qiu,Xue-Dong Zhou et al.
Ya-Ling Jiang et al.
Dental caries are the most prevalent chronic infections in the oral cavity, and Streptococcus mutans acts as the main cariogenic bacterial species. Antibacterial quaternary ammonium compounds (QAs) have been developed to preveFnt or treat d...
Differences in carbon source usage by dental plaque in children with and without early childhood caries [0.03%]
有无早期儿童龋齿儿童牙菌斑碳源利用的差异
Yan Zhao,Wen-Jie Zhong,Zhe Xun et al.
Yan Zhao et al.
Early childhood caries (ECC) is a considerable pediatric and public health problem worldwide. Preceding studies have focused primarily on bacterial diversity at the taxonomic level. Although these studies have provided significant informati...
Study of Sr-Ca-Si-based scaffolds for bone regeneration in osteoporotic models [0.03%]
骨质疏松模型中基于锶-钙-硅的骨再生支架的研究
Qianju Wu,Xiao Wang,Fei Jiang et al.
Qianju Wu et al.
Bone tissue engineering has emerged as a promising alternative therapy for patients who suffer bone fractures or defects caused by trauma, congenital diseases or tumours. However, the reconstruction of bone defects combined with osteoporosi...
Prognostic value of tertiary lymphoid structure and tumour infiltrating lymphocytes in oral squamous cell carcinoma [0.03%]
口腔鳞状细胞癌中三级淋巴结构和肿瘤浸润淋巴细胞的预后价值
Qunxing Li,Xiangqi Liu,Dikan Wang et al.
Qunxing Li et al.
Tertiary lymphoid structures (TLS) are ectopic lymphoid structures in cancers that are largely associated with favourable prognosis. However, the prognostic value of TLSs in oral squamous cell carcinoma (OSCC) is largely unknown, and the as...
Loss of oral mucosal stem cell markers in oral submucous fibrosis and their reactivation in malignant transformation [0.03%]
口腔黏膜干细胞标志物在口腔粘膜纤维化中的丢失及其在恶性转化中的再活化
Mohit Sharma,Felipe Paiva Fonseca,Keith D Hunter et al.
Mohit Sharma et al.
The integrity of the basal stem cell layer is critical for epithelial homoeostasis. In this paper, we review the expression of oral mucosal stem cell markers (OM-SCMs) in oral submucous fibrosis (OSF), oral potentially malignant disorders (...