LITTIP/Lgr6/HnRNPK complex regulates cementogenesis via Wnt signaling [0.03%]
LITTIP/Lgr6/HnRNPK复合体通过Wnt信号调控角质细胞发生
Tiancheng Li,Han Wang,Yukun Jiang et al.
Tiancheng Li et al.
Orthodontically induced tooth root resorption (OIRR) is a serious complication during orthodontic treatment. Stimulating cementum repair is the fundamental approach for the treatment of OIRR. Parathyroid hormone (PTH) might be a potential t...
Carcinoma-associated fibroblast-derived lysyl oxidase-rich extracellular vesicles mediate collagen crosslinking and promote epithelial-mesenchymal transition via p-FAK/p-paxillin/YAP signaling [0.03%]
癌相关成纤维细胞衍生的富含赖氨氧化酶的细胞外囊泡介导胶原交联并通过p-FAK / p-paxillin / YAP信号促进上皮间质转化
Xue Liu,Jiao Li,Xuesong Yang et al.
Xue Liu et al.
Carcinoma-associated fibroblasts (CAFs) are the main cellular components of the tumor microenvironment and promote cancer progression by modifying the extracellular matrix (ECM). The tumor-associated ECM is characterized by collagen crossli...
Extracellular matrix remodelling in dental pulp tissue of carious human teeth through the prism of single-cell RNA sequencing [0.03%]
单细胞RNA测序揭示龋齿人牙髓组织基质重塑的新证据
Anamaria Balic,Dilara Perver,Pierfrancesco Pagella et al.
Anamaria Balic et al.
Carious lesions are bacteria-caused destructions of the mineralised dental tissues, marked by the simultaneous activation of immune responses and regenerative events within the soft dental pulp tissue. While major molecular players in tooth...
Role of dendritic cells in MYD88-mediated immune recognition and osteoinduction initiated by the implantation of biomaterials [0.03%]
髓样树突细胞在MYD88介导的生物材料植入后免疫识别及成骨诱导中的作用研究
Zifan Zhao,Qin Zhao,Hu Chen et al.
Zifan Zhao et al.
Bone substitute material implantation has become an important treatment strategy for the repair of oral and maxillofacial bone defects. Recent studies have shown that appropriate inflammatory and immune cells are essential factors in the pr...
ChatGPT for shaping the future of dentistry: the potential of multi-modal large language model [0.03%]
重塑未来的口腔医学：多模态大型语言模型的潜力（以ChatGPT为例）
Hanyao Huang,Ou Zheng,Dongdong Wang et al.
Hanyao Huang et al.
The ChatGPT, a lite and conversational variant of Generative Pretrained Transformer 4 (GPT-4) developed by OpenAI, is one of the milestone Large Language Models (LLMs) with billions of parameters. LLMs have stirred up much interest among re...
Minimally invasive techniques for lateral maxillary sinus floor elevation: small lateral window and one-stage surgery-a 2-5-year retrospective study [0.03%]
微创上颌窦提升术的侧方开窗宽度及一期植入时机的研究回顾（2-5年）
Shaojingya Gao,Yao Jiang,Yangxue Yao et al.
Shaojingya Gao et al.
This study aimed to introduce a minimally invasive technique for maxillary sinus floor elevation using the lateral approach (lSFE) and to determine the factors that influence the stability of the grafted area in the sinus cavity. Thirty pat...
Salivary biomarkers: novel noninvasive tools to diagnose chronic inflammation [0.03%]
唾液生物标志物：用于诊断慢性炎症的新型非侵入式工具
Paola Dongiovanni,Marica Meroni,Sara Casati et al.
Paola Dongiovanni et al.
Several chronic disorders including type 2 diabetes (T2D), obesity, heart disease and cancer are preceded by a state of chronic low-grade inflammation. Biomarkers for the early assessment of chronic disorders encompass acute phase proteins ...
Oral pathogen aggravates atherosclerosis by inducing smooth muscle cell apoptosis and repressing macrophage efferocytosis [0.03%]
口腔致病菌通过诱导平滑肌细胞凋亡和抑制巨噬细胞摄取作用来加重动脉粥样硬化
Hanyu Xie,Ziyue Qin,Ziji Ling et al.
Hanyu Xie et al.
Periodontitis imparting the increased risk of atherosclerotic cardiovascular diseases is partially due to the immune subversion of the oral pathogen, particularly the Porphyromonas gingivalis (P. gingivalis), by inducing apoptosis. However,...
Periodontitis as a promoting factor of T2D: current evidence and mechanisms [0.03%]
牙周炎作为2型糖尿病促进因素的当前证据及机制分析
Yuan Su,Leilei Ye,Chen Hu et al.
Yuan Su et al.
Periodontitis is an infectious disease caused by an imbalance between the local microbiota and host immune response. Epidemiologically, periodontitis is closely related to the occurrence, development, and poor prognosis of T2D and is recogn...
LIMP-2 enhances cancer stem-like cell properties by promoting autophagy-induced GSK3β degradation in head and neck squamous cell carcinoma [0.03%]
LIMP-2通过促进自噬诱导的GSK3β降解增强头颈部鳞状细胞癌干细胞样特性
Yuantong Liu,Shujin Li,Shuo Wang et al.
Yuantong Liu et al.
Cancer stem cell-like cells (CSCs) play an integral role in the heterogeneity, metastasis, and treatment resistance of head and neck squamous cell carcinoma (HNSCC) due to their high tumor initiation capacity and plasticity. Here, we identi...