Artemisinins inhibit oral candidiasis caused by Candida albicans through the repression on its hyphal development [0.03%]
青蒿素通过抑制白色念珠菌的菌丝发育来抑制口腔白色念珠菌感染
Xiaoyue Liang,Ding Chen,Jiannan Wang et al.
Xiaoyue Liang et al.
Candida albicans is the most abundant fungal species in oral cavity. As a smart opportunistic pathogen, it increases the virulence by switching its forms from yeasts to hyphae and becomes the major pathogenic agent for oral candidiasis. How...
Publisher Correction: The interaction between the nervous system and the stomatognathic system: from development to diseases [0.03%]
出版更正：神经和咀嚼系统的相互作用：从发育到疾病
Yuzhu Wu,Yanhua Lan,Jiajie Mao et al.
Yuzhu Wu et al.
Published Erratum
International journal of oral science. 2023 Sep 11;15(1):39. DOI:10.1038/s41368-023-00250-3 2023
Single-cell transcriptomic analysis uncovers the origin and intratumoral heterogeneity of parotid pleomorphic adenoma [0.03%]
单细胞转录组分析揭示了腮腺多形性腺瘤的起源和瘤内异质性
Xiuyun Xu,Jiaxiang Xie,Rongsong Ling et al.
Xiuyun Xu et al.
Pleomorphic adenoma (PA) is the most common benign tumour in the salivary gland and has high morphological complexity. However, the origin and intratumoral heterogeneity of PA are largely unknown. Here, we constructed a comprehensive atlas ...
Knockdown of PGC1α suppresses dysplastic oral keratinocytes proliferation through reprogramming energy metabolism [0.03%]
PGC1α敲低通过重新编程能量代谢抑制畸形口腔角质细胞增殖
Yunkun Liu,Nengwen Huang,Xianghe Qiao et al.
Yunkun Liu et al.
Oral potentially malignant disorders (OPMDs) are precursors of oral squamous cell carcinoma (OSCC). Deregulated cellular energy metabolism is a critical hallmark of cancer cells. Peroxisome proliferator-activated receptor-gamma coactivator-...
Divergent chondro/osteogenic transduction laws of fibrocartilage stem cell drive temporomandibular joint osteoarthritis in growing mice [0.03%]
生长小鼠颞下颌关节骨关节炎的纤维软骨干细胞分化的软骨和成骨转导规律的分歧性
Ruiye Bi,Qianli Li,Haohan Li et al.
Ruiye Bi et al.
The anterior disc displacement (ADD) leads to temporomandibular joint osteoarthritis (TMJOA) and mandibular growth retardation in adolescents. To investigate the potential functional role of fibrocartilage stem cells (FCSCs) during the proc...
Atp6i deficient mouse model uncovers transforming growth factor-β1 /Smad2/3 as a key signaling pathway regulating odontoblast differentiation and tooth root formation [0.03%]
ATP6I缺陷小鼠模型揭示转化生长因子-β1/SMAD2/3是调节成牙本质细胞分化和根发育的关键信号通路
Jue Wang,Abigail McVicar,Yilin Chen et al.
Jue Wang et al.
The biomolecular mechanisms that regulate tooth root development and odontoblast differentiation are poorly understood. We found that Atp6i deficient mice (Atp6i-/-) arrested tooth root formation, indicated by truncated Hertwig's epithelial...
The interaction between the nervous system and the stomatognathic system: from development to diseases [0.03%]
神经与咀嚼系统间的相互作用：从发育到疾病
Yuzhu Wu,Yanhua Lan,Jiajie Mao et al.
Yuzhu Wu et al.
The crosstalk between the nerve and stomatognathic systems plays a more important role in organismal health than previously appreciated with the presence of emerging concept of the "brain-oral axis". A deeper understanding of the intricate ...
LITTIP/Lgr6/HnRNPK complex regulates cementogenesis via Wnt signaling [0.03%]
LITTIP/Lgr6/HnRNPK复合体通过Wnt信号调控角质细胞发生
Tiancheng Li,Han Wang,Yukun Jiang et al.
Tiancheng Li et al.
Orthodontically induced tooth root resorption (OIRR) is a serious complication during orthodontic treatment. Stimulating cementum repair is the fundamental approach for the treatment of OIRR. Parathyroid hormone (PTH) might be a potential t...
Carcinoma-associated fibroblast-derived lysyl oxidase-rich extracellular vesicles mediate collagen crosslinking and promote epithelial-mesenchymal transition via p-FAK/p-paxillin/YAP signaling [0.03%]
癌相关成纤维细胞衍生的富含赖氨氧化酶的细胞外囊泡介导胶原交联并通过p-FAK / p-paxillin / YAP信号促进上皮间质转化
Xue Liu,Jiao Li,Xuesong Yang et al.
Xue Liu et al.
Carcinoma-associated fibroblasts (CAFs) are the main cellular components of the tumor microenvironment and promote cancer progression by modifying the extracellular matrix (ECM). The tumor-associated ECM is characterized by collagen crossli...
Extracellular matrix remodelling in dental pulp tissue of carious human teeth through the prism of single-cell RNA sequencing [0.03%]
单细胞RNA测序揭示龋齿人牙髓组织基质重塑的新证据
Anamaria Balic,Dilara Perver,Pierfrancesco Pagella et al.
Anamaria Balic et al.
Carious lesions are bacteria-caused destructions of the mineralised dental tissues, marked by the simultaneous activation of immune responses and regenerative events within the soft dental pulp tissue. While major molecular players in tooth...