Exploring the role of stress sensitivity in memory formation: why do some animals learn while others do not? Lessons from Lymnaea stagnalis [0.03%]
Veronica Rivi,Kate Yakubets,Grace Pele et al.
Veronica Rivi et al.
The ability to learn and form memory is critical for survival, yet even genetically similar individuals can vary considerably in their cognitive performance. Using the pond snail Lymnaea stagnalis, we investigated how individual sensitivity...
Know thyself [0.03%]
Jonathon Pines
Jonathon Pines
STIM1 and endoplasmic reticulum-plasma membrane contact sites oscillate independently of calcium-induced calcium release [0.03%]
Ding Xiong,Cheesan Tong,Suet Yin Sarah Fung et al.
Ding Xiong et al.
Calcium (Ca²+) release from intracellular stores, Ca²+ entry across the plasma membrane and their coordination via store-operated Ca²+ entry (SOCE) are critical for receptor-activated Ca²+ oscillations. However, the precise mechanism of...
Konstantinos Stamatiou,Lorena Ligammari,Malki Bothota et al.
Konstantinos Stamatiou et al.
Cellular myelocytomatosis oncogene (MYC) transcription factors are encoded by a family of genes that include the prototype member MYC, MYCN and MYCL, and most human cancers display expression alterations of MYC genes. MYC is regulated at mu...
Transcriptome-wide identification and expression profiling of chemosensory genes in rice grasshopper Oxya intricata (Orthoptera: Acrididae) [0.03%]
水稻草螽(Oxya intricata)味觉和嗅觉基因的鉴定及表达分析
Ran Li,Chao Xue,Dongkai Liu et al.
Ran Li et al.
Chemosensory systems play an essential role in insect survival and reproduction, mediating behaviours such as host location, mating and oviposition. The rice grasshopper Oxya intricata is an important rice pest in Asia, yet the molecular ba...
FRET-based fluorescent sensors for cytosolic and mitochondrial Ca2+ imaging in Drosophila melanogaster [0.03%]
用于斑翅果蝇细胞质和线粒体钙成像的FRET型荧光传感器
Manuela Santalla,Sonia Sonda,Ambra Bertocco et al.
Manuela Santalla et al.
Ca2+ imaging in the living tissues of experimental animals currently presents limitations due to motion artefacts, variable expression levels and the low basal fluorescence of available probes. These issues are even more troublesome when pe...
Mingshu Liang,Magdalena Zernicka-Goetz,Adiyant Lamba et al.
Mingshu Liang et al.
The existence of sex differences in human pre-implantation development remains an open question, with previous attempts based on human observations yielding inconclusive results. In this study, we combined manual annotation and deep learnin...
Histidine and tyrosine residues are targets for SIRT6 ADP-ribosylation activity [0.03%]
丝氨酸/精氨琥珀酸特异性核酸内切酶SIRT6的ADP核糖基化作用位点是他束和酪氨酸残基
Johannes Gregor Matthias Rack,Evgeniia Prokhorova,Raffaella Lauro et al.
Johannes Gregor Matthias Rack et al.
SIRT6, a highly conserved member of the sirtuin family, plays a critical role in diverse cellular processes, including gene regulation, DNA damage response and maintaining nuclear lamina integrity. These functions are essential in contexts ...
Looks can be deceiving: discordances in phylogeny and morphology within loricate choanoflagellates [0.03%]
形态与分子系统发育的不一致性的漏网之鱼——带壳的Choanoflagellatea类群
Alex Gàlvez-Morante,Florentine U Rutaganira,Brian Palenik et al.
Alex Gàlvez-Morante et al.
Choanoflagellates are heterotrophic holozoans that are classified into two groups based on their morphology: loricates, which possess silica-based extracellular structures, and craspedids, which do not. Loricate choanoflagellate taxonomy ha...
Extracellular spike waveform analysis reveals cell type-specific changes in the superior colliculus of fragile X mice [0.03%]
外突触动作电位波形分析揭示了脆性X综合征小鼠上丘的细胞类型特异性变化
Gourav Sharma,Ashley L Russell,Karen G Dixon et al.
Gourav Sharma et al.
Sensory processing deficits are common in neurodevelopmental disorders (NDDs); however, we lack a full understanding of the circuits impacted. The superior colliculus (SC) is a sensorimotor region that directs complex behaviours, which rece...