Removing the noise: endotoxin-free α-synuclein for accurate in vitro screening of fibrillation modulators
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The presence of lipopolysaccharide (LPS) contaminant from the vector expression bacteria Escherichia coli was described as a factor responsible for accelerating the in vitro fibrillation of recombinant α-synuclein (αS), a key protein involved in the neuropat... ...
