Impaired neutralizing antibody response to COVID-19 mRNA vaccines in cancer patients [0.03%]
癌症患者对COVID-19信使rna疫苗的中和抗体反应受损
Cong Zeng,John P Evans,Sarah Reisinger et al.
Cong Zeng et al.
There is currently a critical need to determine the efficacy of SARS-CoV-2 vaccination for immunocompromised patients. In this study, we determined the neutralizing antibody response in 160 cancer patients diagnosed with chronic lymphocytic...
α-Synuclein-mediated neurodegeneration in Dementia with Lewy bodies: the pathobiology of a paradox [0.03%]
路易体痴呆中由α-突触核蛋白介导的神经退行性变：一个悖论的病理生物学
Christopher Simon,Tomoko Soga,Hirotaka James Okano et al.
Christopher Simon et al.
Dementia with Lewy bodies (DLB) is epitomized by the pathognomonic manifestation of α-synuclein-laden Lewy bodies within selectively vulnerable neurons in the brain. By virtue of prion-like inheritance, the α-synuclein protein inexorably ...
NME6 is a phosphotransfer-inactive, monomeric NME/NDPK family member and functions in complexes at the interface of mitochondrial inner membrane and matrix [0.03%]
NME6是NME/NDPK家族的一个单体成员，不能进行磷酸转移，并在 mitochondria内膜和基质界面的复合物中发挥功能。
这里需要说明的是，“NME6”、“phosphotransfer-inactive”、“monomeric”以及“mitochondrial inner membrane and matrix”这些专业术语在生物化学领域有其特定含义，翻译时尽量保持了原意，但为了通顺和理解，做了适当调整。如果用于学术用途，请根据具体上下文进一步核实。
Bastien Proust,Martina Radić,Nikolina Škrobot Vidaček et al.
Bastien Proust et al.
Background: NME6 is a member of the nucleoside diphosphate kinase (NDPK/NME/Nm23) family which has key roles in nucleotide homeostasis, signal transduction, membrane remodeling and metastasis suppression. The well-studied...
Methamphetamine facilitates HIV infection of primary human monocytes through inhibiting cellular viral restriction factors [0.03%]
甲基苯丙胺通过抑制细胞抗病毒限制因子促进人类单核细胞HIV感染
Yu Liu,Feng-Zhen Meng,Xu Wang et al.
Yu Liu et al.
Background: Methamphetamine (METH), a potent addictive psychostimulant, is highly prevalent in HIV-infected individuals. Clinically, METH use is implicated in alteration of immune system and increase of HIV spread/replica...
Methamphetamine facilitates HIV infection of primary human monocytes through inhibiting cellular viral restriction factors [0.03%]
甲基苯丙胺通过抑制细胞病毒限制因子促进HIV单核细胞感染
Yu Liu,Feng-Zhen Meng,Xu Wang et al.
Yu Liu et al.
Background: Methamphetamine (METH), a potent addictive psychostimulant, is highly prevalent in HIV-infected individuals. Clinically, METH use is implicated in alteration of immune system and increase of HIV spread/replica...
Down-regulation of EPB41L4A-AS1 mediated the brain aging and neurodegenerative diseases via damaging synthesis of NAD+ and ATP [0.03%]
EPB41L4A-AS1的下调通过损害NAD+和ATP的合成进而介导了脑衰老和神经退行性疾病的发展
Tingpeng Yang,Yanzhi Wang,Weijie Liao et al.
Tingpeng Yang et al.
Background: Aging and neurodegenerative diseases are typical metabolic-related processes. As a metabolism-related long non-coding RNA, EPB41L4A-AS has been reported to be potentially involved in the development of brain a...
The regulatory mechanism of neutrophil extracellular traps in cancer biological behavior [0.03%]
中性粒细胞胞外陷阱在癌症生物行为中的调控机制
Hui Wang,Yiyin Zhang,Qianling Wang et al.
Hui Wang et al.
As the predominant host defense against pathogens, neutrophil extracellular traps (NETs) have attracted increasing attention due to their vital roles in infectious inflammation in the past few years. Interestingly, NETs also play important ...
Anti-metastatic effect of GV1001 on prostate cancer cells; roles of GnRHR-mediated Gαs-cAMP pathway and AR-YAP1 axis [0.03%]
GV1001对前列腺癌细胞的抗转移作用；GnRHR介导的Gαs-cAMP通路和AR-YAP1轴的作用
Ji Won Kim,Miso Park,Suntae Kim et al.
Ji Won Kim et al.
Background: Gonadotropin-releasing hormone receptor (GnRHR) transmits its signal via two major Gα-proteins, primarily Gαq and Gαi. However, the precise mechanism underlying the functions of Gαs signal in prostate canc...
Parkinson's in the bone [0.03%]
帕金森病与骨骼
Lei Xiong,Jin-Xiu Pan,Hao-Han Guo et al.
Lei Xiong et al.
Patients with Parkinson's disease (PD) exhibit systemic deficits, including arthritis and osteoporosis-like symptoms. However, the questions, how the deficits in periphery organs or tissues occur in PD patients, and what are the relationshi...
Effect of exercise and diet intervention in NAFLD and NASH via GAB2 methylation [0.03%]
GAB2甲基化对运动和饮食干预治疗非酒精性脂肪肝及非酒精性脂肪性肝炎效果的影响
Na Wu,Fan Yuan,Siran Yue et al.
Na Wu et al.
Background: Nonalcoholic fatty liver disease (NAFLD) is a disorder that extends from simple hepatic steatosis to nonalcoholic steatohepatitis (NASH), which is effectively alleviated by lifestyle intervention. Nevertheless...