The role of stem cells and their engineering strategies in the repair of nerve damage in intracerebral hemorrhage [0.03%]
干细胞及其工程策略在脑出血后神经损伤修复中的作用
Liangzhe Wei,He Ren,Yuanwei Lin et al.
Liangzhe Wei et al.
METTL3 stabilizes FASN mRNA by mediating m6A modification to promote malignant progression of diffuse large B-cell lymphoma [0.03%]
METTL3通过介导m6A修饰稳定FASN mRNA促进弥漫性大B细胞淋巴瘤恶性进展
Xiangxiang Song,Yun Zhong,Nasha Yu et al.
Xiangxiang Song et al.
Background: Diffuse large B-cell lymphoma (DLBCL) is an aggressive subtype of non-Hodgkin lymphoma. Fatty acid synthase (FASN) is a key lipogenic enzyme implicated in tumor progression, but its regulation in DLBCL is poor...
Semi-automated isolation of parenchymal and non-parenchymal liver cells from mice and humans with enhanced stellate cell fraction [0.03%]
改良型星状细胞分离小鼠和人类肝实质与非实质细胞的半自动隔离方法
Anne Dropmann,Bedair Dewidar,Kerry Gould et al.
Anne Dropmann et al.
Sevoflurane induces developmental cardiotoxicity via AMPKα2 dysregulation in zebrafish [0.03%]
异氟醚通过AMPKα2调节异常诱导斑马鱼发育期心脏毒性
Huiyu Hao,Yuanhao Li,Xiaoyu Li et al.
Huiyu Hao et al.
Sevoflurane, a widely used volatile anesthetic, has raised concerns regarding its potential developmental toxicity, particularly due to its extensive application in non-obstetric surgeries and fetal intervention procedures during pregnancy....
Correction: RNF186 controls glucose metabolism in metabolic dysfunction-associated fatty liver disease [0.03%]
Correction: RNF186调控代谢功能紊乱相关脂肪性肝病中的葡萄糖代谢
Jiang Du,Qizhang Du,Yuxuan Zhang et al.
Jiang Du et al.
Published Erratum
Cell & bioscience. 2026 Mar 11;16(1):29. DOI:10.1186/s13578-026-01545-8 2026
CASC19 stabilization by ALYREF via m5C modification and its impact on SCD in colorectal cancer cell aggressiveness and stemness [0.03%]
通过m5C修饰的ALYREF稳定CASC19及其对结直肠癌细胞侵袭性和干细胞特性中SCD的影响
Li Zhao,Rongjun Xie,Li Li et al.
Li Zhao et al.
The progression of colorectal cancer (CRC) is closely associated with aberrant epigenetic regulation. As a key regulator of m5C modification, the role and mechanism of Aly/REF export factor (ALYREF) in CRC remain unclear. This study aims to...
The methyltransferase activity of Dot1L is essential for Xenopus tropicalis tadpole development and survival [0.03%]
Dot1L甲基转移酶活性对热带非洲爪蟾蝌蚪发育和存活是必不可少的
Emeric M Louis,Nga Luu,Laurent M Sachs et al.
Emeric M Louis et al.
Epigenetic modifications of histones play key roles in transcriptional regulation by diverse transcription factors. One such modification is the methylation of histone H3 at lysine 79 (H3K79). The methyltransferase DOT1L is the only known, ...
USP30-AS1 functions as a post-transcriptional amplifier of interferon signalling to drive autoimmune pathogenesis [0.03%]
USP30-AS1通过调节干扰素信号转导的转录后放大功能驱动自身免疫性疾病的发生发展
Jie Pan,Min-Yi Feng,Tian Xia et al.
Jie Pan et al.
The mechanisms by which hypothalamic neuroinflammation induced by neonatal cerebral ischemia-hypoxia leads to decreased thymic function via the HPA axis [0.03%]
新生儿脑缺血-缺氧诱发下丘脑神经炎症通过HPA轴降低胸腺功能的机制研究
Gai-Gai Liu,Li-Yan Shuang,Qian Zhang et al.
Gai-Gai Liu et al.
Hypoxic-ischemic encephalopathy (HIE) represents the leading cause of acute neonatal mortality and chronic neurological disorders. The impact of HIE on neonatal immune system development and the underlying mechanisms remain unclear. In this...
NOTCH2NLC GGC repeat expansions cause retinal neurodegeneration in neuronal intranuclear inclusion disease mouse model [0.03%]
NOTCH2NLC GGC重复序列扩增导致神经核内包涵体病小鼠模型视网膜神经退行性变
Haibo Li,Ying Jiang,Lusi Zhang et al.
Haibo Li et al.
Neuronal intranuclear inclusion disease (NIID) patients frequently exhibit ocular abnormalities, yet the pathogenic mechanisms remain unclear. Using a transgenic mouse model ubiquitously expressing NOTCH2NLC with 98GGC repeats, we revealed ...