Potential clinical biomarkers in rheumatoid arthritis with an omic approach [0.03%]
基于组学的类风湿性关节炎潜在临床生物标志物研究
Yolima Puentes-Osorio,Pedro Amariles,Miguel Ángel Calleja et al.
Yolima Puentes-Osorio et al.
Objective: To aid in the selection of the most suitable therapeutic option in patients with diagnosis of rheumatoid arthritis according to the phase of disease, through the review of articles that identify omics biologica...
Effect of janus kinase inhibitors and methotrexate combination on malignancy in patients with rheumatoid arthritis: a systematic review and meta-analysis of randomized controlled trials [0.03%]
Janus激酶抑制剂与甲氨蝶呤联合使用对类风湿关节炎患者恶性肿瘤的影响：随机对照试验的系统评价和meta分析
Vinod Solipuram,Akhila Mohan,Roshniben Patel et al.
Vinod Solipuram et al.
Background: Rheumatoid arthritis (RA) is a systemic autoimmune disease. The combination therapy of methotrexate (MTX) and Janus kinase inhibitor (JAKi) is commonly used. Patients with RA are at increased risk of malignanc...
Short-chain fatty acids and intestinal inflammation in multiple sclerosis: modulation of female susceptibility by microbial products? [0.03%]
短链脂肪酸和多发性硬化肠道炎症：微生物产物如何调节女性易感性？
Anouck Becker,Mosab Abuazab,Andreas Schwiertz et al.
Anouck Becker et al.
Background: Multiple Sclerosis (MS) is an autoimmune-mediated disease of the central nervous system. Experimental data suggest a role of intestinal microbiota and microbial products such as short-chain fatty acids (SCFAs)...
Endogenous mitochondrial double-stranded RNA is not an activator of the type I interferon response in human pancreatic beta cells [0.03%]
内源性线状双链RNA不是人胰岛β细胞I型干扰素反应的激活物
Alexandra Coomans de Brachène,Angela Castela,Anyïshai E Musuaya et al.
Alexandra Coomans de Brachène et al.
Background: Type 1 diabetes (T1D) is an autoimmune disease characterized by the progressive destruction of pancreatic beta cells. Interferon-α (IFNα), an antiviral cytokine, is expressed in the pancreatic islets in earl...
Sustained clinical remission under infliximab/rituximab combination therapy in a patient with granulomatosis with polyangiitis [0.03%]
一例肉芽肿性多血管炎患者接受英夫利西单抗/利妥昔单抗联合治疗后维持临床缓解病例报告
Larissa Valor-Méndez,Arnd Kleyer,Jürgen Rech et al.
Larissa Valor-Méndez et al.
Background: Granulomatosis with polyangiitis (GPA) is a systemic autoimmune disease characterized by small and medium vessel vasculitis. The use of biological therapies such as rituximab and infliximab has improved the tr...
The antinuclear antibody HEp-2 indirect immunofluorescence assay: a survey of laboratory performance, pattern recognition and interpretation [0.03%]
HEp-2细胞间接免疫荧光法检测抗核抗体实验室开展情况、模式识别及结果判断的调查研究
Anne E Tebo,Robert L Schmidt,Kamran Kadkhoda et al.
Anne E Tebo et al.
Background: To evaluate the interpretation and reporting of antinuclear antibodies (ANA) by indirect immunofluorescence assay (IFA) using HEp-2 substrates based on common practice and guidance by the International Consens...
Transformation of fibroblast-like synoviocytes in rheumatoid arthritis; from a friend to foe [0.03%]
类风湿关节炎滑膜成纤维细胞样细胞的转化：从盟友到敌人
Mohammad Javad Mousavi,Jafar Karami,Saeed Aslani et al.
Mohammad Javad Mousavi et al.
Swelling and the progressive destruction of articular cartilage are major characteristics of rheumatoid arthritis (RA), a systemic autoimmune disease that directly affects the synovial joints and often causes severe disability in the affect...
Genetic and molecular biology of systemic lupus erythematosus among Iranian patients: an overview [0.03%]
伊朗系统性红斑狼疮患者的基因和分子生物学概览
Meisam Gachpazan,Iman Akhlaghipour,Hamid Reza Rahimi et al.
Meisam Gachpazan et al.
Background: Systemic lupus erythematosus (SLE) is a clinicopathologically heterogeneous chronic autoimmune disorder affecting different organs and tissues. It has been reported that there is an increasing rate of SLE inci...
ANCA-negative microscopic polyangiitis with diffuse alveolar hemorrhage masquerading as congestive heart failure [0.03%]
以心力衰竭为表现的抗中性粒细胞胞浆抗体阴性的显微镜下多血管炎合并弥漫性肺泡出血病例报告
Arash Mollaeian,Nina Chan,Rohit Aloor et al.
Arash Mollaeian et al.
Background: Microscopic polyangiitis (MPA) is a subtype of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV), involving small and medium sized vessels, often affecting the kidneys and lungs. Anti-neutrophil...
Serum sCTLA-4 level is not associated with type 1 diabetes or the coexistence of autoantibodies in children and adolescent patients from the southern region of Saudi Arabia [0.03%]
沙特阿拉伯南部地区儿童和青少年1型糖尿病患者血清sCTLA-4水平与其自身抗体无相关性
Ahmed Al-Hakami
Ahmed Al-Hakami
Background: The soluble form of CTLA-4 (sCTLA-4) is associated with several autoimmune diseases. The aim of the study is to measure the serum sCTLA-4 levels in type I diabetic (T1DM) patients and to assess the presence of...