Endogenous mitochondrial double-stranded RNA is not an activator of the type I interferon response in human pancreatic beta cells
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Background: Type 1 diabetes (T1D) is an autoimmune disease characterized by the progressive destruction of pancreatic beta cells. Interferon-α (IFNα), an antiviral cytokine, is expressed in the pancreatic islets in early T1D, w... ...
