Fabrication and analysis of a PVP-carboxymethyl chitosan/forsterite nanocomposite scaffold with stainless steel base via freeze-drying and neural network techniques [0.03%]
通过冷冻干燥和神经网络技术制备并分析以不锈钢为基础的PVP-羧甲基壳聚糖/方石英纳米复合支架
Negin Ghanbari,Bahareh Kamyab Moghadas,Fereshteh Samadi et al.
Negin Ghanbari et al.
Objectives: This study aims to design and fabricate innovative polymer-ceramic-metal scaffolds for bone tissue engineering, utilizing 3D printing and freeze-drying techniques to enhance bone repair. ...
Preparation and characterization of decellularized bovine bone as a bioscaffold for bone tissue engineering applications [0.03%]
用于骨组织工程应用的脱细胞牛骨的制备与表征
Roya Akbarpour,Majid Salehi,Simin Nazarnezhad et al.
Roya Akbarpour et al.
Objectives: This study aimed to develop and evaluate decellularized bovine bone (DBB) scaffolds and investigate their potential to promote osteogenic differentiation when combined with Crocin and Alendronate. ...
Comparative effects of estradiol and daidzein on the expression of endometrial cancer-related genes and histopathological parameters in the uterus of ovariectomized rats [0.03%]
雌二醇和大豆异黄酮对卵巢切除大鼠子宫内膜癌相关基因表达及组织学参数的影响比较研究
Vahid Setayesh,Asma Neisy,Maryam Niknam et al.
Vahid Setayesh et al.
Objectives: This study compared the effects of daidzein (DZD) and 17-β-estradiol (E2) on uterine histopathology, expression of endometrial cancer-related genes, and anti-oxidant status in ovariectomized (OVX) rats. ...
Cinnamophilin ameliorates testosterone-induced prostatic hyperplasia and fibrosis by regulating 5α-reductase and TGF-β/Smad signaling pathway [0.03%]
肉桂菲灵通过调节Ⅴα还原酶和TGF-β/Smad信号通路改善雄激素诱导的前列腺增生及纤维化作用
Di Han,Chung-Yi Chen,XiangPeng Huang et al.
Di Han et al.
Objectives: Androgen and TGF-β1/Smad signaling pathways play important roles in epithelial-mesenchymal transition (EMT), fibrosis, and the development of benign prostatic hyperplasia (BPH). Cinnamophilin is extracted fro...
The protective effect of resveratrol on lupus nephritis mice by up-regulating Sirt1 [0.03%]
白藜芦醇通过上调Sirt1保护狼疮性肾炎小鼠肾脏损伤的作用研究
Yu Zhao,Yun Cai,Jie Chen et al.
Yu Zhao et al.
Objectives: To investigate the therapeutic effect and protective mechanism of resveratrol (Res) on mice with lupus nephritis (LN). Materials and methods: ...
Evaluation of cytotoxic, anti-oxidant, and apoptotic effects of Dysphania botrys extract on B16F10 and MCF-7 cell lines [0.03%]
Dysphania botrys提取物的细胞毒性、抗氧化和促凋亡作用评价及其机制研究:B16F10和MCF-7细胞系模型研究
Fatemeh Forouzanfar,Elham Ramazani,Mohammad Esmaeili et al.
Fatemeh Forouzanfar et al.
Objectives: Dysphania botrys (L.) Mosyakin & Clemants (Basionym: Chenopodium botrys L.), belonging to the Amaranthaceae family, has been used for the treatment of inflammation, bacterial and viral infections, and diabetes...
Ficus carica leaf extract ameliorates cardiac injury through Nrf2/Keap1 pathway activation and dual oxidase inhibition [0.03%]
番石榴叶提取物通过Nrf2/Keap1通路活化和双氧化酶抑制改善心脏损伤
Najeeb Ullah Khan,Shamshad Ul Hassan,Bilal Aslam et al.
Najeeb Ullah Khan et al.
Objectives: To investigate the therapeutic potential of Ficus carica leaf extract (FCLE) against high-fat diet (HFD) coupled with isoproterenol-induced cardiac injury in a rat model that mimics myocardial infarction. ...
Temporal dynamics of ferroptosis markers and neuroprotective intervention in cerebral ischemia-reperfusion injury: Insights for therapeutic strategy development [0.03%]
脑缺血再灌注损伤中铁死亡标志物的动态变化及神经保护干预作用：治疗策略研究新见解
Shuangyan Bao,Chaojie Liu,Qian Wang Wang et al.
Shuangyan Bao et al.
Objectives: This study examines the temporal dynamics of ferroptosis following cerebral ischemia-reperfusion injury (CIRI) to establish a theoretical framework for innovative therapies that enhance neuronal survival by mi...
Comparison of the therapeutic effects of sacubitril and valsartan combination versus metformin in experimentally induced polycystic ovary syndrome in rats [0.03%]
比较沙库比曲缬沙坦联用二甲双胍与二甲双胍单独使用治疗实验性大鼠多囊卵巢综合征的疗效
Muhammed Yayla,Bengul Ozdemir Sarikaya,Erdem Toktay et al.
Muhammed Yayla et al.
Objectives: Our study aimed to demonstrate the therapeutic effects of sacubitril (an inhibitor of neprilysin) and/or valsartan (an ARB) in an experimentally induced polycystic ovary syndrome (PCOS) model and in PCOS-induc...
Rhein attenuates obesity-related glomerulopathy by inhibiting the P2X7R/NLRP3 inflammasome pathway and protecting podocytes [0.03%]
赖氨加压素通过抑制P2X7R/NLRP3炎性小体通路并保护足细胞防治肥胖相关性肾小球病
Lifang Wei,Jinwen Zhang,Liangding Dou et al.
Lifang Wei et al.
Objectives: To investigate the renoprotective effects of Rhein in obesity-related glomerulopathy (ORG) by inhibiting the P2X7 receptor (P2X7R)/NOD-like receptor protein 3 (NLRP3) inflammasome pathway. ...