Novel therapeutic topical gel approach for chronic inflammation and pain management in osteo- and viral-arthritis [0.03%]
用于骨关节炎和病毒性关节炎慢性炎症和疼痛管理的新颖治疗凝胶方法
Ayça Altay Benetti,Chiew Yong Ng,Canone Chen Qiuyi et al.
Ayça Altay Benetti et al.
Osteoarthritis is a common and chronic degenerative joint disease that leads to persistent symptoms such as pain, stiffness, swelling, and fatigue, all of which significantly impair mobility and reduce quality of life. Viral infections can ...
Heat-killed Bacteroides fragilis SLAM_BAF01 alleviates weaning-induced stress responses and cognitive impairments by modulating the gut-brain-microbiome axis [0.03%]
热灭活脆弱拟杆菌SLAM_BAF01通过调节肠-脑-微生物轴缓解断奶引起的应激反应和认知障碍
Junha Park,Youbin Choi,Woongji Lee et al.
Junha Park et al.
Weaning transition in porcine industry is marked by nutritional, microbial, and psychological stresses that can impair growth and development. Accumulating evidence indicates that weaning-related stress not only disrupts gut microbial homeo...
Toxin peptides targeting acid-sensing ion channels: Opportunities for cancer diagnosis and therapy [0.03%]
靶向酸感应离子通道的毒肽:癌症诊断与治疗的新机遇
Romain Baudat,Sylvie Diochot,Laura Lange et al.
Romain Baudat et al.
Acid-sensing ion channels (ASICs) are proton-gated cation channels widely expressed throughout the mammalian nervous system, where they play key roles in processes such as neuronal excitability, synaptic plasticity and pain perception. Thei...
Corrigendum to "Pentoxifylline and berberine mitigate diclofenac-induced acute nephrotoxicity in male rats via modulation of inflammation and oxidative stress" [Biomed. Pharmacother. 152 (2022) 113225] [0.03%]
“戊四硝酯和小檗碱通过调节炎症和氧化应激缓解雄性大鼠双氯芬酸引起的急性肾毒性”一文的勘误 [Biomed. Pharmacother. 152 (2022) 113225]
Mohammed Alorabi,Simona Cavalu,Hayder M Al-Kuraishy et al.
Mohammed Alorabi et al.
The Sigma-1 receptor agonist PRE084 improves cardiopulmonary function and remodelling in an experimental model of pulmonary arterial hypertension [0.03%]
σ-1受体激动剂PRE084改善肺动脉高压实验模型的心肺功能及结构重塑作用机制探讨
Marta Villegas-Esguevillas,Bianca Barreira,Ana Hernández-García et al.
Marta Villegas-Esguevillas et al.
Sigma-1 receptors (S1R) are potential pharmacological targets for neurodegenerative diseases and cardiac pathologies, such as cardiac hypertrophy. S1R modulate several cellular functions by interacting with various proteins, including ion c...
CD44v9 as a therapeutic target for antibody-drug conjugate in advanced breast cancer [0.03%]
CD44v9作为抗体-药物偶联物治疗晚期乳腺癌的靶点
Dileep R Reddy,McKenna E Flynn,Yasuaki Anami et al.
Dileep R Reddy et al.
Antibody-drug conjugates (ADCs) have revolutionized breast cancer therapy. HER2 is the only validated biomarker guiding ADC therapy in breast cancer. However, their clinical benefit remains confined to HER2- and TROP2-targeted therapies. Tu...
Retraction notice to ""2-(4-Fluorobenzamido)-4-methylthiazole-5-carboxylic acid" a novel thiazole compound, ameliorates insulin sensitivity and hyperlipidaemia in streptozotocin-induced diabetic rats: Plausible role of inflammatory and oxidative stress markers" [Biomedicine & Pharmacotherapy, 95 (2017) 1232-12 [0.03%]
“2-(4-氟苯甲酰氨基)-4-甲基噻唑-5-羧酸),一种新的噻唑类化合物通过减轻炎症和氧化应激标志物诱导改善链脲佐菌素致糖尿病大鼠的胰岛素抵抗和高脂血症”[Biomedicine & Pharmacotherapy, 95 (2017) 1232-1240]的撤稿声明
Yam Nath Paudel,Md Rahmat Ali,Mohammad Adil et al.
Yam Nath Paudel et al.
AKR1C inhibitors medroxyprogesterone acetate and mefenamic acid exhibit antitumor activity alone and combined with carboplatin in platinum-resistant high-grade serous ovarian cancer models [0.03%]
抗肿瘤药物甲地孕酮和美芬片酸单用及与卡铂联合使用对铂耐药型高级别浆液性卵巢癌模型的作用研究
Nika Marolt,Alja Zottel,Daniela Annibali et al.
Nika Marolt et al.
High-grade serous ovarian carcinoma (HGSOC) is the most lethal form of ovarian carcinoma, primarily because of its tendency to develop platinum resistance. The genes AKR1C1-3 and NFE2L2 are involved in steroid metabolism and cellular detoxi...
Milk fat-globules derived from whey protein phospholipid concentrate prevent high-fat diet induced cognitive impairment in wistar rats in a manner associated with increased brain neuronal connectivity and sphingolipid clearance [0.03%]
由乳清蛋白磷脂浓缩物衍生的奶脂肪球可预防高脂饮食引起的Wistar大鼠认知障碍,并通过增加大脑神经连接和鞘脂清除与之相关联
Duncan A Sylvestre,Nuanyi Liang,James Guinto Galan et al.
Duncan A Sylvestre et al.
Whey protein phospholipid concentrate (WPPC), a co-product of whey protein processing, is enriched in milk fat globules containing phospholipids, glycoconjugates and sugar monomers (e.g. sialic acid) critical to myelin synthesis in the brai...
Corrigendum to "EPICYCLE: A confirmatory preclinical study of the anti-rhabdomyosarcoma efficacy of BET bromodomain and cyclin-dependent kinase 9 inhibitors" [Biomed. Pharmacother. 192 (2025), 118704] [0.03%]
“EPICYCLE:BET溴结构域和周期蛋白依赖性激酶9抑制剂的抗横纹肌肉瘤功效的验证性临床前研究”[Biomed. Pharmacother. 192 (2025),118704]的勘误表
Bernhard Haller,Günther Hs Richter,Marco Wachtel et al.
Bernhard Haller et al.