Corrigendum: "A potential host and virus targeting tool against COVID-19: Chemical characterization, antiviral, cytoprotective, antioxidant, respiratory smooth muscle relaxant effects of Paulownia tomentosa Steud" [Biomed. Pharmacother. 158 (2023) 114083] [0.03%]
有关于“COVID-19潜在的宿主和病毒靶向工具：Paulownia tomentosa Steud化学表征，抗病毒，细胞保护，抗氧化，呼吸平滑肌松弛作用”的勘误声明（发表在Biomed. Pharmacother. 158 (2023) 114083）
Fabio Magurano,Matteo Micucci,Domenico Nuzzo et al.
Fabio Magurano et al.
The apelin/APJ signaling axis in ocular neurovascular disorders: Molecular mechanisms and therapeutic strategies for angiogenesis and neurodegeneration [0.03%]
阿皮林/APJ信号轴在眼神经血管疾病中的作用机制及治疗策略研究：新生血管和神经退行性疾病的角度
Sihan Sang,Hongbo Zhao,Zhiliu Yu et al.
Sihan Sang et al.
The apelin/APJ system, a vital signal axis, regulates key physiological processes in multiple systems, including vascular permeability, inflammatory response and angiogenesis. However, in the pathophysiology of ocular neurovascular disorder...
Evaluation of the immunomodulatory effects of novel phosphinic acid derivatives in vitro and in a murine colitis model [0.03%]
新型磷inic酸衍生物的免疫调节作用的体内外评价研究
Xinhui Zhao,Mingxin Xie,Yutong Li et al.
Xinhui Zhao et al.
T cells and cytokines are key contributors to the pathogenesis of inflammatory bowel disease (IBD), where dysregulated immune activation drives chronic intestinal inflammation. Phosphinic acid compounds are biologically active molecules tha...
Phenolic-rich aqueous extract of Connarus suberosus improves hyperglycaemia and metabolic alterations in streptozotocin-induced diabetic rats [0.03%]
Connarus suberosus富含酚类的水提取物可改善链脲佐菌素诱导的糖尿病大鼠的高血糖和代谢异常
Aline Picolotto,Luis Fernando Nunes Alves Paim,Ana Julia Donada et al.
Aline Picolotto et al.
Aims: To chemically characterise a phenolic-rich aqueous extract of Connarus suberosus Planch. (Connaraceae) leaves and evaluate its antihyperglycaemic, hypolipidaemic, antioxidant, and organ-protective effects in strepto...
Honokiol-mediated reversal of cisplatin-induced transcriptomic changes in outer hair cells [0.03%]
Honokiol介导的顺铂引起的外毛细胞转录改变的逆转
Chail Koo,Robert Fuentes,Prerita Pandya et al.
Chail Koo et al.
Cisplatin-induced hearing loss (CIHL) affects half a million cancer patients annually, but treatment strategies are limited. We have previously shown that honokiol, an antioxidant and otoprotective compound, upregulates mitochondrial sirtui...
Tumor size limits macrophage activation and imaging response to CD47 blockade in osteosarcoma [0.03%]
肿瘤大小限制了成骨肉瘤中CD47阻断的巨噬细胞活化和影像学反应
Raheleh Roudi,Giovanni Marco Saladino,Iryna Vasyliv et al.
Raheleh Roudi et al.
Despite robust preclinical activity, CD47-targeting agents demonstrate limited single-agent efficacy in osteosarcomas. The purpose of our study was to investigate whether tumor size at baseline affects tumor-associated macrophage (TAM) resp...
Hypoxia fuels JAK/STAT-LIV1 signaling: A promising therapeutic avenue in triple-negative breast cancer [0.03%]
缺氧促进JAK/STAT-LIV1信号传导：三阴性乳腺癌治疗的新途径
Harinivas Manthira Moorthi,Devi Rajeswari V
Harinivas Manthira Moorthi
Triple-negative breast cancer remains one of the most aggressive and therapeutically challenging breast cancer subtypes because of its high metastatic potential, molecular heterogeneity and limited targeted treatment options. Hypoxia is a h...
cAmbly, a peptide derived from the star tick Amblyomma sculptum salivary gland transcriptome, attenuates inflammatory pain by activating endogenous opioid pathways [0.03%]
一种从星形八角蜱唾液腺转录组衍生的多肽cAmbly通过激活内源性鸦片类途径来缓解炎症痛
Michelle Cristiane Búfalo,Jorge Luiz Dallazen,Barbara Behr Martins et al.
Michelle Cristiane Búfalo et al.
Pain affects more than 1.5 billion people worldwide and remains a leading cause of disability, but currently available analgesics often have limited efficacy and significant adverse effects. In this context, bioactive molecules derived from...
Diosmetin attenuates chronic unpredictable mild stress induced-depression-like behavior in mice via modulation of oxidative stress, neuroinflammation, and the gut-brain axis [0.03%]
染料木素通过调节氧化应激、神经炎症和脑-肠轴抑制小鼠慢性轻度不可预测应激诱导的类似抑郁的行为
Aparna Ray,Debarati Rakshit,Mohit Nema et al.
Aparna Ray et al.
Depression is a highly prevalent affective disorder, and current pharmacotherapies are often limited by suboptimal efficacy and adverse effects. Diosmetin, a dietary flavonoid, exhibits neuroprotective properties through antioxidant and ant...
Development of a first-in-class homolog-selective, covalent NOX4 inhibitor [0.03%]
一种第一类同源选择性NOX4共价抑制剂的开发
Mariana Castelôa,Sara Marchese,Marta Massari et al.
Mariana Castelôa et al.
The NADPH oxidase (NOX) family in humans includes seven enzymes whose main function is to produce reactive oxygen species. Because of their role in oxidative damage, these enzymes are being explored as targets for new therapies against oxid...