Chemical synthesis and biological activity of semisynthetic derivatives against Chagas disease and leishmaniasis composed of fragments of natural products and 1,2,3-triazine 1-oxide scaffold
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Chagas disease and leishmaniasis are neglected diseases caused by Trypanosoma cruzi and Leishmania sp., respectively, leading to morbidity and mortality worldwide and affecting more than 6 million people per year. Despite the availability of treatments, their ... ...