Correction [0.03%]
改正错误
Published Erratum
Nucleus (Austin, Tex.). 2026 Dec;17(1):2715202. DOI:10.1080/19491034.2026.2715202 2026
More than SAM: mechanisms of action of the Polycomb group protein polyhomeotic [0.03%]
比SAM更多的内容:Polycomb组蛋白polyhomeotic的作用机制
Nanu Pal,Tim M Gemeinhardt,Rowan D H Barrett et al.
Nanu Pal et al.
The Polycomb Group (PcG) system controls developmental transitions and cell states across species. Two main PcG complexes, Polycomb Repressive Complexes 1 and 2 (PRC1, PRC2), regulate transcription and form epigenetic memory through chromat...
The nuclear pore complex as a spatial organizing hub for high-risk DNA lesions [0.03%]
核孔复合体作为高风险DNA损伤的空间组织中心
Dante DeAscanis,Boeun Nam,Hongseon Song et al.
Dante DeAscanis et al.
The nuclear pore complex (NPC) is best known for nucleocytoplasmic transport, but growing evidence implicates nucleoporins and NPC-associated environments in genome maintenance. Here, we discuss the NPC as a spatial organizer of hazardous D...
XPO1-dependent nuclear export regulates NS3 localization and promotes DENV-2 replication through mitochondrial remodeling and interferon suppression [0.03%]
XPO1依赖的核输出调节NS3定位并通过线粒体重塑和抑制干扰素促进DENV-2复制
Selvin Noé Palacios-Rápalo,Jonathan Hernández-Castillo,Luis Adrián De Jesús-González et al.
Selvin Noé Palacios-Rápalo et al.
Nucleocytoplasmic transport is essential for cellular homeostasis and is frequently exploited by viruses during infection. Although dengue virus (DENV) non-structural protein 3 (NS3) undergoes nuclear trafficking, the role of nuclear export...
Repair and misrepair of telomeric DNA in dynamic interactions with PML nuclear bodies and lamin B1 in doxorubicin-treated cancer cells [0.03%]
依托泊苷诱导下癌细胞中端粒DNA的修复及误修复与PML核体和Lamin B1动态相互作用之间的关系
Kristine Salmina,Felikss Rumnieks,Dace Pjanova et al.
Kristine Salmina et al.
Telomeres in epithelial tumors are maintained by telomerase; however, in the MDA-MB-231 breast cancer cell line, treated by doxorubicin (DOX), we found a transient suppression of the telomerase (TERT) before cell growth resumed. Accumulatio...
Elevation of the mechanically-sensitive e protein emerin links nuclear mechanotransduction to tau-induced cytoskeletal remodeling in neurons [0.03%]
机械敏感性E蛋白emerin的活化连接了核力学信号转导与tau诱导的神经元细胞骨架重塑
Claira Sohn,Sammy Pardo,Dana Molleur et al.
Claira Sohn et al.
Neurodegenerative tauopathies, including Alzheimer's disease, are neuropathologically defined by pathological tau deposition. While tau drives neurotoxicity by disrupting cytoskeletal, nucleoskeletal, and genomic architecture, cellular mech...
Nuclear mechanotransduction: tools for mechanical perturbation and chromatin characterization [0.03%]
核机械信号转导:用于机械刺激和染色质表征的工具
Jennifer Soto,Nolan Origer,Yifan Wu et al.
Jennifer Soto et al.
Mechanical cues, ranging from matrix mechanical properties to dynamic mechanical loading, can be transmitted via structural proteins and signaling molecules to the nucleus to reorganize nuclear architecture and modulate chromatin accessibil...
Osman Esen,Edmund Battey,Matthew J Stroud et al.
Osman Esen et al.
Aging leads to a progressive loss of muscle mass and strength, termed sarcopenia, which is accelerated by inactivity and exacerbated by intrinsic cellular and molecular dysfunctions within the muscle fiber. Central to these changes is mecha...
Intrinsically disordered regions facilitate Mlp1-Nab2 recognition in mRNA quality control [0.03%]
固有无序区城可促进mRNA质量检测中Mlp1-Nab2的识别作用
Mohammad Soheilypour,Mohaddeseh Peyro,Hengameh Shams et al.
Mohammad Soheilypour et al.
Quality control of mRNAs ensures that only properly processed transcripts are exported from the nucleus. Myosin-like protein 1 (Mlp1), plays a central role in this process by interacting with RNA-binding proteins (RBPs), including Nab2. Whi...
Zanetta Kechagia,Ohad Medalia
Zanetta Kechagia
The nucleus is a structurally diverse and dynamic organelle that anchors chromatin and orchestrates a large number of essential processes, including transcription, replication, ribosome biogenesis, and nucleocytoplasmic transport. Understan...