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期刊名:Nucleus

缩写:NUCLEUS-PHILA

ISSN:1949-1034

e-ISSN:1949-1042

IF/分区:5.5/Q2

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共收录本刊相关文章索引766
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Nanu Pal,Tim M Gemeinhardt,Rowan D H Barrett et al. Nanu Pal et al.
The Polycomb Group (PcG) system controls developmental transitions and cell states across species. Two main PcG complexes, Polycomb Repressive Complexes 1 and 2 (PRC1, PRC2), regulate transcription and form epigenetic memory through chromat...
Dante DeAscanis,Boeun Nam,Hongseon Song et al. Dante DeAscanis et al.
The nuclear pore complex (NPC) is best known for nucleocytoplasmic transport, but growing evidence implicates nucleoporins and NPC-associated environments in genome maintenance. Here, we discuss the NPC as a spatial organizer of hazardous D...
Selvin Noé Palacios-Rápalo,Jonathan Hernández-Castillo,Luis Adrián De Jesús-González et al. Selvin Noé Palacios-Rápalo et al.
Nucleocytoplasmic transport is essential for cellular homeostasis and is frequently exploited by viruses during infection. Although dengue virus (DENV) non-structural protein 3 (NS3) undergoes nuclear trafficking, the role of nuclear export...
Kristine Salmina,Felikss Rumnieks,Dace Pjanova et al. Kristine Salmina et al.
Telomeres in epithelial tumors are maintained by telomerase; however, in the MDA-MB-231 breast cancer cell line, treated by doxorubicin (DOX), we found a transient suppression of the telomerase (TERT) before cell growth resumed. Accumulatio...
Claira Sohn,Sammy Pardo,Dana Molleur et al. Claira Sohn et al.
Neurodegenerative tauopathies, including Alzheimer's disease, are neuropathologically defined by pathological tau deposition. While tau drives neurotoxicity by disrupting cytoskeletal, nucleoskeletal, and genomic architecture, cellular mech...
Jennifer Soto,Nolan Origer,Yifan Wu et al. Jennifer Soto et al.
Mechanical cues, ranging from matrix mechanical properties to dynamic mechanical loading, can be transmitted via structural proteins and signaling molecules to the nucleus to reorganize nuclear architecture and modulate chromatin accessibil...
Osman Esen,Edmund Battey,Matthew J Stroud et al. Osman Esen et al.
Aging leads to a progressive loss of muscle mass and strength, termed sarcopenia, which is accelerated by inactivity and exacerbated by intrinsic cellular and molecular dysfunctions within the muscle fiber. Central to these changes is mecha...
Mohammad Soheilypour,Mohaddeseh Peyro,Hengameh Shams et al. Mohammad Soheilypour et al.
Quality control of mRNAs ensures that only properly processed transcripts are exported from the nucleus. Myosin-like protein 1 (Mlp1), plays a central role in this process by interacting with RNA-binding proteins (RBPs), including Nab2. Whi...
Zanetta Kechagia,Ohad Medalia Zanetta Kechagia
The nucleus is a structurally diverse and dynamic organelle that anchors chromatin and orchestrates a large number of essential processes, including transcription, replication, ribosome biogenesis, and nucleocytoplasmic transport. Understan...