Unveiling Candida albicans intestinal carriage in healthy volunteers: the role of micro- and mycobiota, diet, host genetics and immune response [0.03%]
健康志愿者肠道白色念珠菌携带状况的初步探索：微生境、饮食、遗传和免疫反应的作用
Margot Delavy,Natacha Sertour,Etienne Patin et al.
Margot Delavy et al.
Candida albicans is a commensal yeast present in the gut of most healthy individuals but with highly variable concentrations. However, little is known about the host factors that influence colonization densities. We investigated how microbi...
Gut feelings: the relations between depression, anxiety, psychotropic drugs and the gut microbiome [0.03%]
胃肠感觉：抑郁症、焦虑症、精神药物和肠道菌群之间的关系
S Brushett,R Gacesa,A Vich Vila et al.
S Brushett et al.
The gut microbiome is involved in the bi-directional relationship of the gut - brain axis. As most studies of this relationship are small and do not account for use of psychotropic drugs (PTDs), we explored the relations of the gut microbio...
The gut-joint axis mediates the TNF-induced RA process and PBMT therapeutic effects through the metabolites of gut microbiota [0.03%]
肠道-关节轴通过肠道菌群代谢物介导TNF诱导的RA进程和PBMT治疗效果
Qingtai Meng,Monan Lin,Wuqi Song et al.
Qingtai Meng et al.
The gut-joint axis, one of the mechanisms that mediates the onset and progression of joint and related diseases through gut microbiota, and shows the potential as therapeutic target. A variety of drugs exert therapeutic effects on rheumatoi...
Escherichia coli triggers α-synuclein pathology in the LRRK2 transgenic mouse model of PD [0.03%]
埃希氏大肠杆菌触发LRRK2转基因小鼠模型中的α-突触核蛋白病理表型
Dongxiao Liang,Han Liu,Ruoqi Jin et al.
Dongxiao Liang et al.
Alpha-synuclein (α-syn) pathology is the hallmark of Parkinson's disease (PD). The leucine-rich repeat kinase 2 (LRRK2) gene is a major-effect risk gene for sporadic PD (sPD). However, what environmental factors may trigger the formation o...
Shari Garrett,Monica C Asada,Jun Sun
Shari Garrett
Classically, Axin1 is considered a regulator of Wnt/β-catenin signaling. However, Axin1's roles in host-microbial interactions have been unknown. Our recent study has demonstrated that deletion of intestinal epithelial Axin1 in epithelial ...
Loss of claudin-3 expression increases colitis risk by promoting Gut Dysbiosis [0.03%]
Claudin-3表达缺失通过促进肠道菌群紊乱增加肠炎风险
Rizwan Ahmad,Balawant Kumar,Ishwor Thapa et al.
Rizwan Ahmad et al.
Dysregulation of both the gut barrier and microbiota (dysbiosis) promotes susceptibility to and severity of Inflammatory Bowel Diseases (IBD). Leaky gut and dysbiosis often coexist; however, potential interdependence and molecular regulatio...
Alterations in gut virome are associated with cognitive function and minimal hepatic encephalopathy cross-sectionally and longitudinally in cirrhosis [0.03%]
肝硬化患者肠道病毒组的改变与认知功能和最小肝性脑病的横断面及纵向相关性研究
Thananya Jinato,Masoumeh Sikaroodi,Andrew Fagan et al.
Thananya Jinato et al.
Cognitive dysfunction due to minimal hepatic encephalopathy (MHE) adversely impacts patients with cirrhosis and more precise therapies are needed. Gut-brain axis changes are therapeutic targets, but prior studies have largely focused on bac...
Multi-omics analyses demonstrate the modulating role of gut microbiota on the associations of unbalanced dietary intake with gastrointestinal symptoms in children with autism spectrum disorder [0.03%]
多组学分析展示了肠道菌群在不平衡饮食摄入与自闭症儿童胃肠症状关联中的调节作用
Hailin Li,Churui Liu,Saijun Huang et al.
Hailin Li et al.
Our previous work revealed that unbalanced dietary intake was an important independent factor associated with constipation and gastrointestinal (GI) symptoms in children with autism spectrum disorder (ASD). Growing evidence has shown the al...
Nuanced contribution of gut microbiome in the early brain development of mice [0.03%]
肠道微生物组对小鼠早期大脑发育的贡献
Xin Yi Yeo,Woo Ri Chae,Hae Ung Lee et al.
Xin Yi Yeo et al.
The complex symbiotic relationship between the mammalian body and gut microbiome plays a critical role in the health outcomes of offspring later in life. The gut microbiome modulates virtually all physiological functions through direct or i...
Engraftment of aging-related human gut microbiota and the effect of a seven-species consortium in a pre-clinical model [0.03%]
老化相关的人体肠道微生物群的植入及七种菌株合剂的效果评估在临床前模型中的作用研究
Huimin Ye,Tarini S Ghosh,Cara M Hueston et al.
Huimin Ye et al.
Human aging is characterized by gut microbiome alteration and differential loss of gut commensal species associated with the onset of frailty. The administration of cultured commensal strains to replenish lost taxa could potentially promote...