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Diane E Hoffmann,Gail H Javitt,Colleen R Kelly et al. Diane E Hoffmann et al.
Fecal microbiota transplantation (FMT) is a procedure involving the transfer of intestinal microbiota from a healthy donor to a patient to restore a functional intestinal microbiome. First described in modern science in 1958, the use of FMT...
Multi-species probiotic supplement enhances vagal nerve function - results of a randomized controlled trial in patients with depression and healthy controls [0.03%] 多菌株益生菌补充剂可改善迷走神经功能—抑郁症患者和健康人的随机对照试验结果
Sabrina Mörkl,Martin Narrath,Daria Schlotmann et al. Sabrina Mörkl et al.
Major depression (MD) significantly impacts individual well-being and society. The vagus nerve plays a pivotal role in the gut-brain axis, facilitating bidirectional communication between these systems. Recent meta-analyses suggest potentia...
Q112.22024 Randomized Controlled Trial Gut microbes. 2025 Dec;17(1):2492377. DOI:10.1080/19490976.2025.2492377 2025
Role of insulinemic and inflammatory dietary patterns on gut microbial composition and circulating biomarkers of metabolic health among older American men [0.03%] 炎症性和生理性饮食模式对美国老年男性肠道微生物组成及循环代谢标志物的影响研究
Sushma Nepal,Ni Shi,Rebecca Hoyd et al. Sushma Nepal et al.
Chronic low-grade inflammation and hyperinsulinemia are linked with metabolic dysfunction and dysbiosis. This study investigated the role of dietary inflammatory and insulinemic potential on gut microbiome and circulating health biomarkers ...
Mechanosensory Piezo2 regulated by gut microbiota participates in the development of visceral hypersensitivity and intestinal dysmotility [0.03%] 肠道微生物调节的机械感受器Piezo2参与内脏高敏感及肠动力异常的发展
Haonan Zheng,Yuzhu Chen,Siqi Lu et al. Haonan Zheng et al.
The gut microbiota plays a crucial role in the manifestation of intestinal dysfunction associated with irritable bowel syndrome (IBS). The mechanosensory Piezo2 has been implicated in the regulation of intestinal function. However, it remai...
Tong Jin,Si-Yuan Li,Hong-Li Zheng et al. Tong Jin et al.
The gut microbiota has been linked to a number of neurological disorders. However, it is unclear whether the gut microbiota is involved in the genesis of chronic itch, a refractory condition that afflicts patients both physically and mental...
High-resolution analysis of the treated coeliac disease microbiome reveals strain-level variation [0.03%] 高分辨率分析治疗乳糜泻微生物组揭示了菌株水平的差异
Jelle Slager,Hanna L Simpson,Ranko Gacesa et al. Jelle Slager et al.
Background: Coeliac disease (CeD) is an immune-mediated disorder primarily affecting the small intestine, characterized by an inflammatory immune reaction to dietary gluten. CeD onset results from a multifaceted interplay...
Bacillus coagulans ameliorates inflammatory bone loss in post-menopausal osteoporosis via modulating the "Gut-Immune-Bone" axis [0.03%] 芽孢乳杆菌通过调节“肠-免疫-骨”轴缓解绝经后骨质疏松症的炎症性骨丢失
Leena Sapra,Chaman Saini,Pradyumna K Mishra et al. Leena Sapra et al.
Osteoporosis is a systemic skeletal disease that leads to lower bone mineral density and intensifies the risk of unexpected fractures. Recently, our group reported that numerical defect in the frequencies of Bregs along with their compromis...
Gut microbiota regulates hepatic ketogenesis and lipid accumulation in ketogenic diet-induced hyperketonemia by disrupting bile acid metabolism [0.03%] 肠道微生物群通过破坏胆汁酸代谢调节生酮饮食引起的高酮血症中的肝酮体生成和脂质蓄积
Zhengzhong Luo,Yixin Huang,Kang Yong et al. Zhengzhong Luo et al.
The ketogenic diet (KD) induces prolonged hyperketonemia, characterized by elevated circulating level of β-hydroxybutyrate. However, the KD can negatively affect host metabolic health by altering the gut microbial community. Despite this, ...
Helminth reshapes host gut microbiota and immunoregulation by deploying an antimicrobial program of innate immunity [0.03%] 肠道寄生蠕虫通过调动宿主先天免疫的抗菌程序重塑肠道菌群及免疫调节
Yang Zou,Lixia Pu,Aijiang Guo et al. Yang Zou et al.
Helminths can manipulate their host's gut microbiota, with the expansion of the lactobacilli population being a common feature. This process profoundly influences host immunoregulation, yet the underlying mechanisms remain almost unknown. U...
Gut microbiota and associated metabolites: key players in high-fat diet-induced chronic diseases [0.03%] 肠道微生物群及其相关代谢物：高脂饮食诱导的慢性病的主要参与者
Wei Du,Zhen-Ping Zou,Bang-Ce Ye et al. Wei Du et al.
Excessive intake of dietary fats is strongly associated with an increased risk of various chronic diseases, such as obesity, diabetes, hepatic metabolic disorders, cardiovascular disease, chronic intestinal inflammation, and certain cancers...