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Escherichia coli triggers α-synuclein pathology in the LRRK2 transgenic mouse model of PD

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Alpha-synuclein (α-syn) pathology is the hallmark of Parkinson's disease (PD). The leucine-rich repeat kinase 2 (LRRK2) gene is a major-effect risk gene for sporadic PD (sPD). However, what environmental factors may trigger the formation of α-syn pathology i... ...