Zebrafish as a preclinical model for diabetes mellitus and its complications: From monogenic to gestational diabetes and beyond [0.03%]
斑马鱼作为糖尿病及其并发症的临床前模型：从单基因糖尿病到妊娠糖尿病等
Jie Huang,Yin-Ling Chen
Jie Huang
With diabetes currently affecting 537 million people globally, innovative research approaches are urgently required. Zebrafish (Danio rerio) has emerged as a pivotal model organism in diabetes research, particularly valuable for development...
Targeting gut microbiota and its associated metabolites as a potential strategy for promoting would healing in diabetes [0.03%]
靶向肠道菌群及其相关代谢物以促进糖尿病创面修复的潜在策略
Ling Xiong,Ya-Xin Huang,Lan Mao et al.
Ling Xiong et al.
Impaired healing of diabetic wounds is one of the most important complications of diabetes, often leading to lower limb amputations and incurring significant economic and psychosocial costs. Unfortunately, there are currently no effective p...
Impaired efferocytosis by monocytes and monocyte-derived macrophages in patients with poorly controlled type 2 diabetes [0.03%]
2型糖尿病患者单核细胞和单核细胞衍生巨噬细胞的清除功能受损
Qian-Yun Mao,Hui Ran,Qiu-Yue Hu et al.
Qian-Yun Mao et al.
Background: Deficient efferocytosis (i.e., phagocytic clearance of apoptotic cells) by macrophages has been frequently reported in experimental models of type 2 diabetes (T2D). ...
Na Wang,Tian-Yi Zhao,Xiao Ma
Na Wang
Background: Previous research yielded conflicting results regarding the association between prediabetes and colorectal cancer (CRC). Aim: ...
Shenfushu granules attenuate diabetic kidney disease by inhibiting PIK3R1/protein kinase B/heparanase-mediated endothelial-mesenchymal transition [0.03%]
肾素颗粒通过抑制PIK3R1/蛋白激酶B/肝素酶介导的内皮间质转化缓解糖尿病肾脏疾病
Xi-Ding Yang,Si-Jia Ma,Da-Xiong Xiang et al.
Xi-Ding Yang et al.
Background: Injury to the glomerular filtration barrier causes diabetic kidney disease (DKD), and glomerular endothelial-mesenchymal transition damages the filtration barrier of glomerular endothelial cells. Shenfushu gra...
Effect of beinaglutide, a thrice-daily GLP-1 receptor agonist, on body weight and metabolic parameters: A systematic review and meta-analysis [0.03%]
贝加鲁肽对体重和代谢参数的影响：系统评价和meta分析
Abul Bashar Mohammad Kamrul-Hasan,Vanishri Ganakumar,Lakshmi Nagendra et al.
Abul Bashar Mohammad Kamrul-Hasan et al.
Background: Beinaglutide, a short-acting glucagon-like polypeptide-1 receptor agonist, has shown variable efficacy in weight reduction and metabolic control in randomized controlled trials (RCTs). ...
Various classification methods for diabetes mellitus in the management of blood glucose control [0.03%]
糖尿病血糖管理的各种分类方法
Qing Jiang,Yun Hu,Jian-Hua Ma
Qing Jiang
In the era of precision medicine, the classification of diabetes mellitus has evolved beyond the traditional categories. Various classification methods now account for a multitude of factors, including variations in specific genes, type of ...
Effect of ranibizumab on diabetic retinopathy via the vascular endothelial growth factor/STAT3/glial fibrillary acidic protein pathway [0.03%]
雷珠单抗通过血管内皮生长因子/信号转导子和转录激活子3/胶质纤维酸性蛋白通路对糖尿病视网膜病变的影响研究
Ye-Ting Lin,Jian Tan,Yu-Lin Tao et al.
Ye-Ting Lin et al.
Background: Diabetic retinopathy (DR) is the leading cause of vision loss in patients with diabetes. The vascular endothelial growth factor (VEGF) pathway plays a critical role in the pathogenesis of DR, and ranibizumab, ...
Comparisons of various insulin resistance indices for new-onset metabolic syndrome before midlife: The CHIEF cohort study, 2014-2020 [0.03%]
基于CHIEF队列研究的新发代谢综合征患者发病前各胰岛素抵抗指数的比较（2014-2020年）
Wei-Nung Liu,Yi-Chiung Hsu,Yen-Po Lin et al.
Wei-Nung Liu et al.
Background: Some non-insulin-based insulin resistance (IR) indices have been found to be associated with metabolic syndrome (MetS); however, few cohort studies have compared the capacities of these indices for predicting ...
Saptarshi Bhattacharya,Cornelius J Fernandez,Abul Bashar Mohammad Kamrul-Hasan et al.
Saptarshi Bhattacharya et al.
Monogenic diabetes is a heterogeneous disorder characterized by hyperglycemia arising from defects in a single gene. Maturity-onset diabetes of the young (MODY) is the most common type with 14 subtypes, each linked to specific mutations aff...