Indirect bilirubin is inversely associated with diabetic retinopathy risk and is a potential predictive biomarker [0.03%]
间接胆红素与糖尿病视网膜病变风险呈负相关且是一个潜在的预测生物标志物
Xiao-Ying Lin,Yi-Xuan Zheng,Meng-Meng Liu et al.
Xiao-Ying Lin et al.
Background: Diabetic retinopathy (DR) is a major cause of visual impairment and blindness. However, the current DR biomarkers are insufficient for accurately predicting its onset. ...
Macrophage and inflammation in diabetes and metabolic dysfunction-associated steatotic liver disease: From mechanisms to therapeutic strategies [0.03%]
糖尿病和代谢功能障碍相关脂肪变性肝病中的巨噬细胞与炎症：从机制到治疗策略
Chun-Ye Zhang,Shuai Liu,Ming Yang
Chun-Ye Zhang
Metabolic dysfunction-associated steatotic liver disease (MASLD) is featured by the accumulation of excessive fat in the liver. It is caused by many factors, such as overweight, obesity, diabetes, and high plasma levels of sugar, cholestero...
Postprandial C-peptide is more relevant to hemoglobin A1c levels and diabetic microvascular complications than fasting C-peptide in type 2 diabetes [0.03%]
餐后C肽比空腹C肽更相关于2型糖尿病患者HbA1c水平及糖尿病微血管并发症的关系
Zheng Wang,Ming-Qun Deng,Li-Xin Guo et al.
Zheng Wang et al.
Background: Type 2 diabetes mellitus (T2DM), driven by insulin resistance and β cell dysfunction, necessitates reliable assessment of β cell function. C-peptide (CP) measurement, a stable marker of endogenous insulin se...
Income and wealth inequality is associated with young-onset type 2 diabetes [0.03%]
收入和财富不平等与青年发病的2型糖尿病有关
Fu-Shun Yen,James Cheng-Chung Wei,Yao-Min Hung et al.
Fu-Shun Yen et al.
Background: There are only a few studies on the influence of economic inequalities on young-onset type 2 diabetes (T2D). Aim: To examin...
Managing diabetic ketoacidosis in special conditions: Difficulties and dilemmas [0.03%]
特殊条件下的糖尿病酮症酸中毒管理：困难与抉择
Sayantan Ray,Rajan Palui
Sayantan Ray
The management of diabetic ketoacidosis can be challenging in high-risk patients. Recent studies have reported a significant increase in diabetic ketoacidosis hospitalization rates. While managing this high-risk condition, patient factors a...
β-cell dedifferentiation in type 2 diabetes: Interplay of metabolic stress, endoplasmic reticulum dysfunction, and forkhead box protein O1 inhibition [0.03%]
2型糖尿病中的β细胞去分化：代谢压力、内质网功能障碍和叉头盒蛋白O1抑制之间的相互作用
Ashraf Al Madhoun,Fatemah Bahman,Rasheed Ahmad
Ashraf Al Madhoun
In this editorial, we highlight the study by Wang et al published in a recent issue of the World Journal of Diabetes. Type 2 diabetes is increasingly recognized as a β-cell dysfunction disorder, with apoptosis and dedifferentiation being k...
Spatial transcriptomics meets diabetic kidney disease: Illuminating the path to precision medicine [0.03%]
空间转录组学与糖尿病肾脏病：精准医疗之路的探索
Dan-Dan Liu,Han-Yue Hu,Fei-Fei Li et al.
Dan-Dan Liu et al.
Diabetic kidney disease (DKD), a primary cause of end-stage renal disease, results from progressive tissue remodeling and loss of kidney function. While single-cell RNA sequencing has significantly accelerated our understanding of cellular ...
Farrerol ameliorates diabetic cardiomyopathy by inhibiting ferroptosis via miR-29b-3p/SIRT1 signaling pathway in endothelial cells [0.03%]
法拉瑞醇通过微调内皮细胞中miR-29b-3p/SIRT1信号通路抑制铁死亡从而改善糖尿病心肌病
Yan Guo,Xin-Rou Yu,Hao-Di Gu et al.
Yan Guo et al.
Background: Diabetic cardiomyopathy (DCM) is the leading cause of cardiovascular disease-related mortality. Farrerol (FA) possesses anti-inflammatory and antioxidant properties. However, its role in regulating endothelial...
Diabetic gastrointestinal autonomic neuropathy: Integrating neuronal degeneration and gut microbial dysbiosis [0.03%]
糖尿病胃肠自主神经病变：整合神经元变性和肠道微生物群失调
Mei-Xia Zhou,Yu Zhao,Chen-Ling Chu et al.
Mei-Xia Zhou et al.
Diabetic gastrointestinal autonomic neuropathy (DGAN) is a common and debilitating complication of diabetes, characterized by autonomic dysfunction in the gastrointestinal system. The complex pathophysiology of DGAN involves neuronal injury...
Exploring the relationship between health knowledge, health literacy, self-care, self-efficacy, and glycemic control among adults with type 2 diabetes mellitus [0.03%]
探索2型糖尿病成人健康知识、健康素养、自我照顾、自我效能和血糖控制之间的关系
Sasikala D Amirthalingam,Malanashita Ganeson,Chandramani Thuraisingham et al.
Sasikala D Amirthalingam et al.
Background: Adults with type 2 diabetes mellitus (T2DM) in Malaysia continue to have substantial comorbidities and struggle to achieve glycemic targets. A...