O-linked β-N-acetylglucosamine transferase regulates macrophage polarization in diabetic periodontitis: In vivo and in vitro study [0.03%]
O连接的β-N-乙酰葡糖胺转移酶通过调节极化巨噬在糖尿病牙周炎中的作用：一项体内和体外研究
Ye-Ke Wu,Min Liu,Hong-Ling Zhou et al.
Ye-Ke Wu et al.
Background: Periodontitis, when exacerbated by diabetes, is characterized by increased M1 macrophage polarization and decreased M2 polarization. O-linked β-N-acetylglucosamine (O-GlcNAcylation), catalyzed by O-GlcNAc tra...
Effects of glycemic indicators on early neurological outcomes in patients with acute ischemic stroke treated with intravenous thrombolysis [0.03%]
血糖指标对静脉溶栓治疗的急性缺血性卒中患者早期神经功能预后的影响
Zuo-Wei Duan,Zhi-Ning Li,Yu-Jia Zhai et al.
Zuo-Wei Duan et al.
Background: Stress hyperglycemia (SH) is a common phenomenon that is present in about 50% of patients with acute ischemic stroke (AIS). It is thought to be a main risk factor for poor functional outcome among patients wit...
Association between serum retinol-binding protein and lower limb atherosclerosis risk in type 2 diabetes mellitus [0.03%]
血清视黄醇结合蛋白与2型糖尿病下肢动脉粥样硬化风险的相关性研究
Yu-Ling Zhang,Gui-Liang Peng,Wei-Ling Leng et al.
Yu-Ling Zhang et al.
Background: Serum retinol-binding protein (RBP) is the primary transport protein of circulating vitamin A. RBP has a crucial role in maintaining nutrient metabolism and physiologic homeostasis. Several studies have indica...
Continuum of glucose and bone metabolism impairment across autonomous cortisol secretion: A cross-sectional study [0.03%]
自主皮质醇分泌量上的血糖及骨代谢损害的连续性变化：一项横断面研究
Min-Min Han,Xiao-Ming Cao,Zi-Ang Liu et al.
Min-Min Han et al.
Background: Autonomous cortisol secretion (ACS) is linked to a higher prevalence of metabolic abnormalities and an increased risk of major adverse cardiovascular events. ...
Risk factors and a predictive model of diabetic foot in hospitalized patients with type 2 diabetes [0.03%]
住院2型糖尿病病人发生糖尿病足的危险因素及预测模型研究
Ming-Zhuo Li,Fang Tang,Ya-Fei Liu et al.
Ming-Zhuo Li et al.
Background: The risk factors and prediction models for diabetic foot (DF) remain incompletely understood, with several potential factors still requiring in-depth investigations. ...
From metabolic regulation to kidney protection: β-arrestin 2 as a dual-function therapeutic target [0.03%]
从代谢调节到肾脏保护：β- arrestin 2作为双功能治疗靶点
Jian Yang,Cheng-Zhi Zhang,Jing Zhang
Jian Yang
We are deeply interested in the recent findings on β-arrestin 2. Liu et al demonstrated that β-arrestin 2 knockout provides significant protection in diabetic nephropathy, underscoring its potential as a promising therapeutic target for d...
Optimizing risk management for post-amputation wound complications in diabetic patients: Focus on glycemic and immunosuppressive control [0.03%]
糖尿病患者截肢后伤口并发症的风险管理优化：重点是血糖和免疫抑制控制
Zhi-Peng Li,Jin-Ke Sun,Wei-Ping Fu et al.
Zhi-Peng Li et al.
This study highlights the importance of identifying and addressing risk factors associated with wound complications following transtibial amputation in diabetic patients. These amputations, often necessitated by severe diabetic foot ulcers,...
Li-Juan Nie,Zhe Cheng,Yi-Xian He et al.
Li-Juan Nie et al.
Background: The duodenum plays a significant role in metabolic regulation, and thickened mucous membranes are associated with insulin resistance. Duodenal mucosal resurfacing (DMR), a new-style endoscopic procedure using ...
N6-methyladenosine methyltransferase Wilms tumor 1-associated protein impedes diabetic wound healing through epigenetically activating DNA methyltransferase 1 [0.03%]
Wilms肿瘤1相关蛋白通过表观遗传激活DNA甲基转移酶1阻碍糖尿病伤口愈合
Ren-Jie Xiao,Tian-Jiao Wang,Dan-Yin Wu et al.
Ren-Jie Xiao et al.
Background: Diabetic wound injury is a significant and common complication in individuals with diabetes. N6-methyladenosine (m6A)-related epigenetic regulation is widely involved in the pathogenesis of diabetes complicati...
Electroacupuncture relieves type 2 diabetes by regulating gut microbiome [0.03%]
电针通过调节肠道微生物群来缓解二型糖尿病
Ya-Jing Yang,Xu-Chang Zhou,Hao-Ran Tian et al.
Ya-Jing Yang et al.
Cumulative studies have shown that the composition of the gut microbiome is strongly associated with the development of type 2 diabetes mellitus (T2DM). Electroacupuncture (EA) therapy has been reported to alleviate various diseases, includ...