Antidiabetic combination therapy and cardiovascular outcomes: An evidence-based approach [0.03%]
基于证据的抗糖尿病联合治疗与心血管结局的关系
Vanishri Ganakumar,Cornelius J Fernandez,Joseph M Pappachan
Vanishri Ganakumar
Type 2 diabetes mellitus is associated with a 2-4 times increased risk of cardiovascular (CV) disease. Glucagon-like polypeptide-1 receptor agonists (GLP1RA) and sodium-glucose cotransporter-2 inhibitors (SGLT2i) are two important classes o...
Increased blood urea nitrogen levels and compromised peripheral nerve function in patients with type 2 diabetes [0.03%]
2型糖尿病患者血尿素氮水平升高及外周神经功能受损
Rui Wang,Yu-Xian Xu,Feng Xu et al.
Rui Wang et al.
Background: Increased blood urea nitrogen (BUN) levels have been demonstrated to be associated with broader metabolic disturbances and the incidence of type 2 diabetes (T2D), potentially playing a role in the development ...
Exploring a novel mechanism for targeting β-arrestin-2 in the management of diabetic nephropathy [0.03%]
探索针对糖尿病肾病管理中靶向β-arrestin-2的新机制
Na Liu,Wei-Tao Yan,Kun Xiong
Na Liu
Diabetic nephropathy (DN) is a well-known microvascular complication in patients with diabetes mellitus, which is characterized by the accumulation of extracellular matrix in the glomerular and tubulointerstitial compartments, along with th...
Coronary imaging characteristics and risk factors in patients with type 2 diabetes mellitus with coronary heart disease complication [0.03%]
2型糖尿病合并冠心病患者冠脉影像学特征及危险因素分析
Chang-Jie Pan,Tao Wang,Ruo-Han Yin et al.
Chang-Jie Pan et al.
Background: Coronary heart disease (CHD) is a prevalent type 2 diabetes mellitus (T2DM) complication. Further, the risk stratification before angiography may help diagnose T2DM with CHD early. However, few studies have in...
Elevated waist-to-hip ratio, as an abdominal obesity index, predicts the risk of diabetic kidney injury [0.03%]
增高的腰臀比，作为中心性肥胖的指标之一，预测糖尿病肾损伤的风险
Di-Ni Lin,Dan Li,Meng-Meng Peng et al.
Di-Ni Lin et al.
Background: Diabetic nephropathy (DN) is associated with a high incidence of type 2 diabetic mellitus (T2DM) in Asia. Central obesity is an important risk factor for DN, represented by a series of indices, including waist...
B-type natriuretic peptide efficacy compared to fragmented QRS for diastolic dysfunction screening in patients with type 2 diabetes [0.03%]
与QRS片段化相比，脑钠肽B型对2型糖尿病患者舒张功能不全筛查的有效性研究
Kunimasa Yagi,Daisuke Chujo,Isao Usui et al.
Kunimasa Yagi et al.
Background: Early diagnosis of left ventricular diastolic dysfunction (LVDD) is essential for preventing heart failure. B-type natriuretic peptide (BNP) is a viable marker for predicting LVDD, as elevated BNP levels have ...
Systematic review and critical appraisal of predictive models for diabetic peripheral neuropathy: Existing challenges and proposed enhancements [0.03%]
糖尿病外周神经病变预测模型的系统评价和批判性评估：现有挑战及改进措施
Chao-Fan Sun,Yu-Han Lin,Guo-Xing Ling et al.
Chao-Fan Sun et al.
Background: The trend of risk prediction models for diabetic peripheral neuropathy (DPN) is increasing, but few studies focus on the quality of the model and its practical application. ...
Intracellular calcium channels: Potential targets for type 2 diabetes mellitus? [0.03%]
胞内钙通道：潜在的2型糖尿病治疗靶点？
Jia-Xuan Zhu,Zhao-Nan Pan,Dan Li
Jia-Xuan Zhu
Type 2 diabetes mellitus (T2DM) is a prevalent metabolic disorder. Despite the availability of numerous pharmacotherapies, a range of adverse reactions, including hypoglycemia, gastrointestinal discomfort, and lactic acidosis, limits their ...
Curcumol ameliorates diabetic retinopathy via modulating fat mass and obesity-associated protein-demethylated MAF transcription factor G antisense RNA 1 [0.03%]
姜黄素类似物curcumol通过调节脂肪质量和肥胖相关蛋白去甲基化MAFG反义RNA改善糖尿病视网膜病变
Han Rong,Yu Hu,Wei Wei
Han Rong
Background: Diabetic retinopathy (DR) is a major microvascular complication of diabetes mellitus, leading to significant visual impairment and blindness among adults. Current treatment options are limited, making it essen...
MicroRNA-122-5p is upregulated in diabetic foot ulcers and decelerates the transition from the inflammatory to the proliferative stage [0.03%]
miR-122-5p在糖尿病足溃疡中高表达并可延缓创面从炎症期向增殖期过渡
Mei-Jie Yuan,He-Chen Huang,Hong-Shuo Shi et al.
Mei-Jie Yuan et al.
Background: Shifting from the inflammatory to the proliferative phase represents a pivotal step during managing diabetic foot ulcers (DFUs); however, existing medical interventions remain insufficient. MicroRNAs (miRs) hi...