Prolactin and growth hormone aggregates in secretory granules: the need to understand the structure of the aggregate [0.03%]
泌乳素和生长激素聚合体在分泌颗粒中的结构研究
Priscilla S Dannies
Priscilla S Dannies
Prolactin and GH form reversible aggregates in the trans-Golgi lumen that become the dense cores of secretory granules. Aggregation is an economical means of sorting, because self-association removes the hormones from other possible pathway...
John R Ussher,Daniel J Drucker
John R Ussher
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that enhances glucose-stimulated insulin secretion and exerts direct and indirect actions on the cardiovascular system. GLP-1 and its related incretin hormone, glucose-dependent insulin...
Elizabeth A Townsend,Virginia M Miller,Y S Prakash
Elizabeth A Townsend
Sex differences in the biology of different organ systems and the influence of sex hormones in modulating health and disease are increasingly relevant in clinical and research areas. Although work has focused on sex differences and sex horm...
Childhood obesity in developing countries: epidemiology, determinants, and prevention [0.03%]
发展中国家的儿童肥胖症：流行病学、决定因素和预防措施
Nidhi Gupta,Kashish Goel,Priyali Shah et al.
Nidhi Gupta et al.
Rapidly changing dietary practices and a sedentary lifestyle have led to increasing prevalence of childhood obesity (5-19 yr) in developing countries recently: 41.8% in Mexico, 22.1% in Brazil, 22.0% in India, and 19.3% in Argentina. Moreov...
Emerging role of mast cells and macrophages in cardiovascular and metabolic diseases [0.03%]
心血管和代谢性疾病中髓样细胞的作用越来越重要
Jia-Ming Xu,Guo-Ping Shi
Jia-Ming Xu
Mast cells are essential in allergic immune responses. Recent discoveries have revealed their direct participation in cardiovascular diseases and metabolic disorders. Although more sophisticated mechanisms are still unknown, data from anima...
Stacey Jamieson,Peter J Fuller
Stacey Jamieson
Granulosa cell tumors of the ovary (GCT) comprise a distinct subset of ovarian cancers that account for approximately 5% of all ovarian malignancies. They are thought to arise from normal proliferating granulosa cells of the late preovulato...
Islets transplanted in immunoisolation devices: a review of the progress and the challenges that remain [0.03%]
免疫隔离装置移植胰岛细胞的研究进展与挑战
Esther S O&#x;Sullivan,Arturo Vegas,Daniel G Anderson et al.
Esther S O&#x;Sullivan et al.
The concept of using an immunoisolation device to facilitate the transplantation of islets without the need for immunosuppression has been around for more than 50 yr. Significant progress has been made in developing suitable materials that ...