Evidence for a continuum of genetic, phenotypic, and biochemical abnormalities in children with growth hormone insensitivity
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GH insensitivity (GHI) presents in childhood as growth failure and in its severe form is associated with dysmorphic and metabolic abnormalities. GHI may be caused by genetic defects in the GH-IGF-I axis or by acquired states such as chronic illness. This artic... ...
