Elaine A Ostrander
Elaine A Ostrander
The Edward Novitski Prize recognizes creativity and intellectual ingenuity in the solution of problems in genetics research. The prize honors scientific experimental work-either a single experimental accomplishment or a body of work. Ostran...
Science from the soul: original research by middle and high school students addresses community health needs and increases representation in science [0.03%]
源于灵魂的科学:中学生原创研究助力社区健康并提升科学界多样性
Dara M Ruiz-Whalen,Alana M OReilly
Dara M Ruiz-Whalen
Harmit S Malik
Harmit S Malik
Trait imputation enhances nonlinear genetic prediction for some traits [0.03%]
性状补充分别增强了某些性状的非线遗传预测力
Ruoyu He,Jinwen Fu,Jingchen Ren et al.
Ruoyu He et al.
The expansive collection of genetic and phenotypic data within biobanks offers an unprecedented opportunity for biomedical research. However, the frequent occurrence of missing phenotypes presents a significant barrier to fully leveraging t...
Genetic background affects the strength of crossover interference in house mice [0.03%]
遗传背景影响小家鼠中的互换干扰强度
Andrew P Morgan,Bret A Payseur
Andrew P Morgan
Meiotic recombination is required for faithful chromosome segregation in most sexually reproducing organisms and shapes the distribution of genetic variation in populations. Both the overall rate and the spatial distribution of crossovers v...
An anatomical atlas of Drosophila melanogaster-the wild-type [0.03%]
果蝇(Drosophila melanogaster)野生型解剖图谱
Kai J Jürgens,Maik Drechsler,Achim Paululat
Kai J Jürgens
Scanning electron microscopy is the method of choice to visualize the surface structures of animals, fungi, plants, or inorganic objects at the highest resolution and often with impressive appeal. Numerous scanning electron microscope (SEM)...
Conserved signaling modules regulate filamentous growth in fungi: a model for eukaryotic cell differentiation [0.03%]
保守的信号模块调节真菌丝状体生长:一种真核细胞分化的模型
Matthew D Vandermeulen,Michael C Lorenz,Paul J Cullen
Matthew D Vandermeulen
Eukaryotic organisms are composed of different cell types with defined shapes and functions. Specific cell types are produced by the process of cell differentiation, which is regulated by signal transduction pathways. Signaling pathways reg...
Transcriptomic analysis of meiotic genes during the mitosis-to-meiosis transition in Drosophila females [0.03%]
在果蝇雌性有丝分裂向减数分裂转变过程中的转录组分析及我对其的贡献与看法
Ana Maria Vallés,Thomas Rubin,Nicolas Macaisne et al.
Ana Maria Vallés et al.
Germline cells produce gametes, which are specialized cells essential for sexual reproduction. Germline cells first amplify through several rounds of mitosis before switching to the meiotic program, which requires specific sets of proteins ...
Linkage equilibrium between rare mutations [0.03%]
稀有突变间的平衡.linkage equilibrium between rare mutationsLINKAGE EQUILIBRIUM BETWEEN RARE MUTATIONS
Anastasia S Lyulina,Zhiru Liu,Benjamin H Good
Anastasia S Lyulina
Recombination breaks down genetic linkage by reshuffling existing variants onto new genetic backgrounds. These dynamics are traditionally quantified by examining the correlations between alleles, and how they decay as a function of the reco...
Defects in the central metabolism prevent thymineless death in Escherichia coli, while still allowing significant protein synthesis [0.03%]
中心代谢缺陷可阻止大肠杆菌胸腺嘧啶缺乏致死现象,但仍允许其进行大量蛋白质合成
Sharik R Khan,Andrei Kuzminov
Sharik R Khan
Starvation of Escherichia coli thyA auxotrophs for the required thymine or thymidine leads to the cessation of DNA synthesis and, unexpectedly, to thymineless death (TLD). Previously, TLD-alleviating defects were identified by the candidate...