Defects in the central metabolism prevent thymineless death in Escherichia coli, while still allowing significant protein synthesis
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Starvation of Escherichia coli thyA auxotrophs for the required thymine or thymidine leads to the cessation of DNA synthesis and, unexpectedly, to thymineless death (TLD). Previously, TLD-alleviating defects were identified by the candidate gene approach, for ... ...
