Coexistence of piRNA and KZFP defense systems: Evolutionary dynamics of layered defense against transposable elements [0.03%]
piRNA和KZFP防御系统的共存：层层防控转座子的进化动态
Yusuke Nabeka,Hideki Innan
Yusuke Nabeka
Transposable elements (TEs) pose a persistent threat to genome stability, and host organisms have consequently evolved sophisticated defense mechanisms to restrain them. In animals, the most prominent systems include PIWI-interacting RNAs (...
Creation and manipulation of bipartite expression transgenes in C. elegans using phiC31 recombinase [0.03%]
利用phiC31重组酶在秀丽线虫中创建和操作双元表达转基因
Michael L Nonet
Michael L Nonet
Bipartite expression systems are widely used in model organisms to express specific gene products in a cell-specific context. They are typically encoded as two independent, unlinked transgenic insertions: a driver and a reporter. Herein, I ...
Inherited long telomeres induce a genome-wide transcriptional response in budding yeast [0.03%]
端粒酶延长的端粒在酿酒酵母中引起的全基因组转录反应
Vasilisa Sidarava,David Lydall
Vasilisa Sidarava
Eukaryotes typically maintain telomere length within a defined range. While short telomeres are known to activate DNA damage responses and limit cell proliferation, long telomeres are associated with extended proliferative capacity. The bro...
Adaptive Dynamics of Quantitative Traits in a Steadily Changing Environment [0.03%]
稳态变化环境下的数量性状适应动态研究
Sakshi Pahujani,Yuna Zhang,Markus G Stetter et al.
Sakshi Pahujani et al.
Understanding the adaptation of quantitative traits to changing environments is a central challenge in evolutionary biology. However, the precise roles of the speed of environmental change and trait architecture in adaptive dynamics remain ...
Functional Landscape of Zebrafish Gonadotropins and Receptors: A Comprehensive Genetic Analysis [0.03%]
斑马鱼促性腺激素和受体功能景观的全面遗传分析
Chu Zeng,Zhiwei Zhang,Lingling Zhou et al.
Chu Zeng et al.
In vertebrates, reproduction is primarily controlled by two master hormones, or gonadotropins, from the pituitary: follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which act through their cognate receptors, FSHR and LHCGR, i...
Synergistic actions of Nup43 and Myosin VI drive actin cone assembly during Drosophila spermiogenesis [0.03%]
Nup43和Myosin VI的协同作用驱动果蝇精子发生过程中肌动蛋白锥的组装
Jyotsna Kawadkar,Ashley Suraj Hermon,Rohit Kumar et al.
Jyotsna Kawadkar et al.
Nuclear pore complexes, composed of nucleoporins (Nups), are critical for bidirectional nucleocytoplasmic transport and regulate various cellular processes, thus contributing significantly to organismal development. Intriguingly, the integr...
Identification of two Cryptococcus neoformans heme transporters involved in Fhb1-mediated nitrosative stress protection in a fission yeast model [0.03%]
模式裂殖酵母中鉴定参与FHB1介导的亚硝化应激保护的两组新克萨斯酵母血红素转运蛋白
Florie Lo Ying Ping,Samuel Plante,Giulia Boriosi et al.
Florie Lo Ying Ping et al.
In Schizosaccharomyces pombe and Cryptococcus neoformans, the flavohemoglobins (flavoHbs) that protect these yeasts against nitrosative stress are Yhb1 and Fhb1, respectively. Although heme is an essential cofactor for flavoHb activity, the...
Analysis of a hypomorphic mei-P26 mutation reveals coordination between developmental programming of germ cells and meiotic chromosome dynamics [0.03%]
解析mei-P26低渗突变揭示发育编程与减数分裂染色体动力学之间的协调关系
Joseph Terry,Ally Solomon,Amanda M Powell et al.
Joseph Terry et al.
Female gametogenesis in Drosophila melanogaster requires differentiation and mitotic division of germ cells, acquisition of oocyte fate, and entry into meiosis. Each of these processes is well understood individually; however, little is kno...
Neural and Genetic Mechanisms Regulating Copulation Latency in Male Drosophila melanogaster [0.03%]
调控黑腹果蝇雄性交配潜伏期的神经和遗传机制
Hongyu Miao,Tianmu Zhang,Yutong Song et al.
Hongyu Miao et al.
This study investigates the factors influencing copulation latency (CL) in male Drosophila melanogaster, a crucial determinant of reproductive fitness. We explore the interplay between genetic, environmental, and social factors that shape m...
Joseph Schacherer
Joseph Schacherer
The Genetics Society of America Medal honors an individual member of the Society for their contributions to the field of genetics at the midcareer level (up to 15 years since starting an independent position). The society established the GS...