Poly (3-hydroxybutyrate-co-3-hydroxyhexanoate)/collagen hybrid scaffolds for tissue engineering applications [0.03%]
聚(3-羟基丁酸-co-3-羟基己酸)/胶原杂化支架的制备及其组织工程应用研究
Alex J Lomas,William R Webb,JianFeng Han et al.
Alex J Lomas et al.
The benefits associated with polyhydroxyalkanoates (PHA) in tissue engineering include high immunotolerance, low toxicity, and biodegradability. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx), a molecule from the PHA family of biopo...
Determining the optimal decellularization and sterilization protocol for preparing a tissue scaffold of a human-sized liver tissue [0.03%]
用于制备人体尺寸肝组织的组织支架的最优脱细胞和灭菌方案的选择
Abdol-Mohammad Kajbafzadeh,Niloufar Javan-Farazmand,Maryam Monajemzadeh et al.
Abdol-Mohammad Kajbafzadeh et al.
Attaining a well-qualified whole decellularized organ applicable for an enduring and successful transplantation, decellularization protocols should be organ specific in terms of decellularizing agents and time of tissue exposure. Since a bi...
Enhanced hyaline cartilage matrix synthesis in collagen sponge scaffolds by using siRNA to stabilize chondrocytes phenotype cultured with bone morphogenetic protein-2 under hypoxia [0.03%]
低氧条件下使用siRNA稳定骨形态发生蛋白-2诱导的软骨细胞表型以增强胶原海绵支架中的透明质酸基质合成
Florence Legendre,David Ollitrault,Magalie Hervieu et al.
Florence Legendre et al.
Cartilage healing by tissue engineering is an alternative strategy to reconstitute functional tissue after trauma or age-related degeneration. However, chondrocytes, the major player in cartilage homeostasis, do not self-regenerate efficien...
A mathematical model for analyzing the elasticity, viscosity, and failure of soft tissue: comparison of native and decellularized porcine cardiac extracellular matrix for tissue engineering [0.03%]
一种分析软组织弹性和黏性以及失败的数学模型：用于组织工程天然和去细胞化猪心脏细胞外基质的比较研究
Tomer Bronshtein,Gigi Chi Ting Au-Yeung,Udi Sarig et al.
Tomer Bronshtein et al.
The clinical success of tissue-engineered constructs commonly requires mechanical properties that closely mimic those of the human tissue. Determining the viscoelastic properties of such biomaterials and the factors governing their failure ...
Dual contrast agent for computed tomography and magnetic resonance hard tissue imaging [0.03%]
计算机断层扫描和磁共振硬组织成像的双重造影剂
Manuela Ventura,Yi Sun,Viorel Rusu et al.
Manuela Ventura et al.
Calcium phosphate cements (CPCs) are commonly used bone substitute materials, which closely resemble the composition of the mineral phase of bone. However, this high similarity to natural bone also results in difficult discrimination from t...
1-step versus 2-step immobilization of alkaline phosphatase and bone morphogenetic protein-2 onto implant surfaces using polydopamine [0.03%]
基于多巴胺一步法和两步法制备骨形态发生蛋白-2/碱性磷酸酶双功能涂层钛种植体表面的研究
Arnold W G Nijhuis,Jeroen J J P van den Beucken,Otto C Boerman et al.
Arnold W G Nijhuis et al.
Immobilization of biomolecules onto implant surfaces is highly relevant in many areas of biomaterial research. Recently, a 2-step immobilization procedure was developed for the facile conjugation of biomolecules onto various surfaces using ...
A novel alternative to cryopreservation for the short-term storage of stem cells for use in cell therapy using alginate encapsulation [0.03%]
一种用于细胞治疗的新型替代冷冻保存技术：使用藻酸盐包埋法短期储存干细胞
Bo Chen,Bernice Wright,Rashmita Sahoo et al.
Bo Chen et al.
Efficient transport of stem/progenitor cells without affecting their survival and function is a key factor in any practical cell-based therapy. However, the current approach using liquid nitrogen for the transfer of stem cells requires a sh...
Process quality engineering for bioreactor-driven manufacturing of tissue-engineered constructs for bone regeneration [0.03%]
生物反应器驱动制造组织工程构建物以进行骨再生的质量工程过程学研究
Ioannis Papantoniou Ir,Yoke Chin Chai,Frank P Luyten et al.
Ioannis Papantoniou Ir et al.
The incorporation of Quality-by-Design (QbD) principles in tissue-engineering bioprocess development toward clinical use will ensure that manufactured constructs possess prerequisite quality characteristics addressing emerging regulatory re...
Isolation of viable human hepatic progenitors from adult livers is possible even after 48 hours of cold ischemia [0.03%]
人肝脏干细胞的分离不受供肝冷缺血时间(48小时)的影响
Sophie Aupet,Gael Simoné,Bruno Heyd et al.
Sophie Aupet et al.
Liver transplantation, utilized routinely for end-stage liver disease, has been constrained by the paucity of organ donors, and is being complemented by alternative strategies such as liver cell transplantation. One of the most promising fo...
Biomimetic three-dimensional anisotropic geometries by uniaxial stretch of poly(ε-caprolactone) films for mesenchymal stem cell proliferation, alignment, and myogenic differentiation [0.03%]
聚-ε-己内酯膜单轴拉伸制备仿生三维各向异性结构促进间充质干细胞增殖、排列及肌源性分化
Zu-yong Wang,Erin Yiling Teo,Mark Seow Khoon Chong et al.
Zu-yong Wang et al.
Anisotropic geometries are critical for eliciting cell alignment to dictate tissue microarchitectures and biological functions. Current fabrication techniques are complex and utilize toxic solvents, hampering their applications for translat...