An Ex Vivo Mini-Tumor Culture Protocol for Evaluating Individualized Efficacy of Chemotherapy and Immunotherapy [0.03%]
体外培养小肿瘤用于评估化疗和免疫疗法有效性的个体化差异的实验方案
Yuanfeng Fu,Yuxia Zou,Zhilong Chen et al.
Yuanfeng Fu et al.
Conventional drug screening models face a series of challenges in guiding individualized cancer treatment, including time-consuming processes, limited drug coverage, and insufficient accuracy in efficacy evaluation. This study aims to estab...
Low-Cost, Rapid Fabrication of Customizable Polyethylene Glycol-Based Cell Culture Devices [0.03%]
低成本且快速的制造聚乙二醇细胞培养器件的方法
Emily L Pallack,Maxwell W Oulundsen,Yan Kolpakov et al.
Emily L Pallack et al.
Biological research groups may face a high barrier to entry when constructing custom 3D cell culture devices to investigate multi-tissue interactions in vitro. Standard fabrication methods such as lithography, etching, or molding are expens...
Ceri-Anne E Suurmond,Natasja W M van Dijk,René van Rheden et al.
Ceri-Anne E Suurmond et al.
Patients with breast or prostate cancer have a high chance of developing bone metastasis, which is associated with many skeletal-related events. The development of novel bone metastasis treatments is lagging behind due to the lack of reliab...
Three-Dimensional Perfusion Imaging of Microcirculatory Networks Within Axially Vascularized Artificial Tissue [0.03%]
轴向血管化的人工组织内微循环网络的三维灌注成像
Christoph Koepple,Lukas Pollmann,Nicola Sariye Pollmann et al.
Christoph Koepple et al.
Evaluating the complex, three-dimensional (3D) architecture of de novo angiogenesis in artificially engineered tissue remains a significant challenge, as conventional methods like 2D histology and microimaging techniques are limited. For ax...
Evaluation of Safety and Efficacy of a Novel Alginate-Based Esophageal Mucosal Wound Protective Gel [0.03%]
评估一种新型海藻酸盐基质的食管黏膜伤口保护凝胶的安全性和疗效
Han Wang,Jiaqi Li,Minyi Yang et al.
Han Wang et al.
Background & objective: Endoscopic Submucosal Dissection (ESD) effectively treats early gastric cancer, but postoperative complications limit its clinical use. Therefore, this study examines how esophageal mucosal wound p...
In Vitro MSC Characterization of Cryopreserved Adipose Stromal Cells Processed via Uvence Workflow [0.03%]
紫外线细胞处理的冷冻保存的脂肪间充质干细胞的体外特性分析
Ahsan A Khan,Olivier D Amar,Sumila Rathnayaka M et al.
Ahsan A Khan et al.
Adipose tissue is an abundant and clinically accessible source of stromal cells. Stromal vascular fraction (SVF) and nanofat have been widely investigated for their regenerative potential; however, commercial systems vary considerably in yi...
The Evolving Landscape of Colorectal Organoids in Tissue Engineering: Research Trends and Hotspots [0.03%]
结肠直肠类器官在组织工程中的研究趋势与热点——技术景观变迁与发展机遇
Huiping Gan,Pan Huang,Jia Wang et al.
Huiping Gan et al.
Colorectal organoids, which accurately replicate the structure and function of the human colorectal epithelium, have become a valuable platform in a broad spectrum of fundamental biological research and clinical applications. This study emp...
Optimizing Decellularized Human Umbilical Vein as a Scaffold for Vascular Tissue Engineering [0.03%]
优化脱细胞化的人脐静脉作为血管组织工程的支架
Danang Himawan Limanto,Thomas Jatiman,Ni Kadek Sulistyaningsih et al.
Danang Himawan Limanto et al.
Background: The demand for effective vascular grafts continues to increase with the increasing prevalence of cardiovascular disease. The decellularized human umbilical vein (HUV) offers a promising scaffold for cellular r...
Andreza S Andrada,Daniel A Maria,Sidney N da Silva et al.
Andreza S Andrada et al.
Over the past four decades, calcium phosphate cements (CPCs) have emerged as promising materials for bone repair due to their biocompatibility, osteoconductivity, and in situ hardening properties. Developed from a combination of calcium pho...
Marissa R Perez,Vasiliki K Kolliopoulos,Sadhana A Chari et al.
Marissa R Perez et al.
Bioprinting continues to expand as a preferred fabrication technology as new biomaterials emerge. These biomaterials must be biocompatible, in addition to exhibiting suitable printing characteristics. Printability is usually gauged by metri...