Subretinal Transplant of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium on Nanostructured Fibrin-Agarose [0.03%]
纳米结构纤粘蛋白-琼脂糖上的诱导多能干细胞源性视网膜色素上皮亚视网膜移植
Ana B García Delgado,Berta de la Cerda,Julia Alba Amador et al.
Ana B García Delgado et al.
In the promising field of cellular therapy for retinal degenerative diseases, a new biomaterial is proposed as a scaffold to grow and surgically introduce a monolayer of retinal pigment epithelial cells into the subretinal space, keeping th...
Tunable Microstructured Membranes in Organs-on-Chips to Monitor Transendothelial Hydraulic Resistance [0.03%]
用于监测血管通透性的小器官芯片中可调微结构膜的研究
Pritam Das,Andries D van der Meer,Aisen Vivas et al.
Pritam Das et al.
Tissue engineering is an interdisciplinary field, wherein scientists from different backgrounds collaborate to address the challenge of replacing damaged tissues and organs through the in vitro fabrication of functional and transplantable b...
A Biomimicking Polymeric Cryogel Scaffold for Repair of Critical-Sized Cranial Defect in a Rat Model [0.03%]
一种仿生聚合物 cryogel 基架用于修复大鼠颅骨缺损模型中的大型颅骨缺陷
Chuntao Liu,Chaowen Lin,Xiaoreng Feng et al.
Chuntao Liu et al.
Mineralized polymeric cryogels with interconnective macroporous structure have demonstrated their potential as promising scaffolding material in bone tissue engineering. However, their capability in inducing osteogenic differentiation of me...
Jihye Baek,Martin K Lotz,Darryl D D&#x;Lima
Jihye Baek
Electrospinning is an attractive method of fabricating nanofibers that replicate the ultrastructure of the human meniscus. However, it is challenging to approximate the mechanical properties of meniscal tissue while maintaining the biocompa...
Decellularized Annulus Fibrosus Matrix/Chitosan Hybrid Hydrogels with Basic Fibroblast Growth Factor for Annulus Fibrosus Tissue Engineering [0.03%]
用于纤维环组织工程的脱细胞纤维环基质/壳聚糖杂化水凝胶及其应用基本成纤维细胞生长因子
Chen Liu,Zhongxing Jin,Xin Ge et al.
Chen Liu et al.
Low back pain caused by degenerative disc disease affects many people worldwide and brings huge economical burden. Thus, attentions have focused on annulus fibrosus (AF) tissue engineering for treatment of intervertebral disc degeneration. ...
Application of External Force Regulates the Migration and Differentiation of Adipose-Derived Stem/Progenitor Cells by Altering Tissue Stiffness [0.03%]
外加力通过改变组织硬度调控脂肪来源干细胞的迁移和分化
Ye Li,Mengfan Wu,Ziang Zhang et al.
Ye Li et al.
Large soft-tissue defects are challenging to reconstruct surgically. Expansion of soft tissue using an external volume expansion (EVE) device is a noninvasive method to improve such reconstruction; however, the underlying mechanism is uncle...
Human Mast Cell Development from Hematopoietic Stem Cells in a Connective Tissue-Equivalent Model [0.03%]
人肥大细胞的体外分化及诱导因素的研究进展
Tahereh Derakhshan,Rudra Bhowmick,James H Meinkoth et al.
Tahereh Derakhshan et al.
Mast cells (MCs) play critical roles in the pathogenesis of IgE- and non-IgE-mediated immune responses, as well as host defense against parasites, bacteria, and viruses. Due to the effect of extracellular matrix components on tissue morphog...
Autologous Platelet-Rich Plasma (CuteCell PRP) Safely Boosts In Vitro Human Fibroblast Expansion [0.03%]
自体富血小板血浆（CuteCell PRP）可安全促进人的成纤维细胞的体外增殖
Sarah Berndt,Antoine Turzi,Brigitte Pittet-Cuénod et al.
Sarah Berndt et al.
Nowadays autologous fibroblast application for skin repair presents an important clinical interest. In most cases, in vitro skin cell culture is mandatory. However, cell expansion using xenogeneic or allogenic culture media presents some di...
In Silico and In Vivo Studies Detect Functional Repair Mechanisms in a Volumetric Muscle Loss Injury [0.03%]
计算机模拟和体内实验检测体积型肌肉损失损伤的修复机制
Juliana A Passipieri,Xiao Hu,Ellen Mintz et al.
Juliana A Passipieri et al.
Despite medical advances, volumetric muscle loss (VML) injuries to craniofacial muscles represent an unmet clinical need. We report an implantable tissue-engineered construct that leads to substantial tissue regeneration and functional reco...