From Chemistry to Clinic: Polysaccharide-Bioceramic Composites for Tissue Engineering Applications [0.03%]
从化学到临床：组织工程应用的多糖-生物陶瓷复合材料
Nilgun Yakubogullari,Hilal Deniz Yilmaz-Dagdeviren,Ahu Arslan-Yildiz
Nilgun Yakubogullari
Composite scaffolds combining polysaccharides and bioceramics represent next-generation scaffolds extensively investigated in tissue engineering (TE) and biomedical applications. Polysaccharides such as chitosan, hyaluronic acid, and pectin...
Development of a 3D in Vitro Wound Healing Model to Assess the Effect of ADSC-EVs on Vascularization [0.03%]
用于评估ADSC-EVs对血管化作用的三维体外伤口愈合模型的建立
Emma K C Symonds,Alfonso J Schmidt,Alexander W Brown et al.
Emma K C Symonds et al.
Angiogenesis is critical for effective wound healing and relies on the successful coordination of various cell types, including endothelial cells, macrophages, and fibroblasts. Adipose-derived stem cell extracellular vesicles (ADSC-EVs) hav...
LINC00687 Regulates PRDX2 Expression in High Glucose-Induced Nonunion after Digital Replantation [0.03%]
高血糖诱导的断指再植不愈合中长链非编码RNA LINC00687对过氧化物酶体丙二醛抗氧化酶2表达的调控作用
Xiangying Wang,Xin He
Xiangying Wang
Diabetic nonunion is a major clinical challenge with unclear molecular mechanisms. This study systematically investigated the key genes and molecular mechanisms of bone nonunion after finger replantation induced by high glucose using Gene E...
Jiahe Li,Liang Zhou,Mingxiao Liu et al.
Jiahe Li et al.
Successful osseointegration is crucial for dental implant stability, yet it remains challenging due to adverse local microenvironments, particularly infection and inflammation. While carbon monoxide (CO) has been recognized as a promising g...
Tissue-Engineered Endothelial Keratoplasty with Controlled Cell Density: Toward Super TEEKs [0.03%]
具有可控细胞密度的组织工程角膜内皮移植向超级TEEKs发展
Inès Aouimeur,Louise Coulomb,Sofiane Fraine et al.
Inès Aouimeur et al.
Over the past 20 years, endothelial keratoplasty procedures have revolutionized the treatment of corneal endothelial disorders. These conditions have now become the leading indication for corneal transplantation in Western countries and acc...
Developing a Functional Osteoarthritis Model Using Human Osteochondral-Synovial Explants [0.03%]
基于人骨软骨-滑膜组织片的膝骨关节炎功能模型构建及其应用研究
Luminita Labusca,Camelia-Mihaela Zara-Danceanu,Anca Emanuela Minuti et al.
Luminita Labusca et al.
Osteochondral explants can serve as valuable ex vivo models for investigating joint development and testing therapeutic interventions in osteoarthritis (OA). The incorporation of synovial tissue in coculture settings more closely reproduces...
Electrically Triggered Fluorescein and Dexamethasone Release from Conducting Polymer Hydrogels [0.03%]
导电聚合物水凝胶中电气触发的荧光素和醋酸倍他米松释放
Matthew S Horrocks,Kirill E Zhurenkov,Matthew S Ting et al.
Matthew S Horrocks et al.
Spatially and temporally controlled drug delivery is an important field to address the limitations of conventional pharmaceutical administration. While many effective controlled drug delivery systems exist, the repertoire of systems that ad...
Sage S Frehner,Matthew Fainor,Galina Dulatov et al.
Sage S Frehner et al.
Cell and tissue engineering therapies provide promise for regenerating damaged intervertebral disc (IVD) tissue and resolving the low back pain that often accompanies it. However, these treatments remain experimental and unavailable for pat...
Chitosan Bioceramic Composites for Bone Regeneration: Insights from In Vitro and In Vivo Studies [0.03%]
基于体外和体内研究的壳聚糖生物陶瓷复合材料的骨再生性能研究
Jeffrey Huang,Jithendra Ratnayake,Maree Gould et al.
Jeffrey Huang et al.
Bone-related pathologies due to injuries, trauma, and disease are a burden on the current health system that will only continue to grow as the population's life expectancy increases. The field of biomaterials aims to address these concerns ...