Human Mast Cell Development from Hematopoietic Stem Cells in a Connective Tissue-Equivalent Model
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Mast cells (MCs) play critical roles in the pathogenesis of IgE- and non-IgE-mediated immune responses, as well as host defense against parasites, bacteria, and viruses. Due to the effect of extracellular matrix components on tissue morphogenesis and cell beha... ...