Investigation of the Resistome of non- Helicobacter pylori Helicobacter Species [0.03%]
非Helicobacter pylori幽门螺旋杆菌的抗性基因组研究
Lucie Bénéjat,Elodie Sifré,Astrid Ducournau et al.
Lucie Bénéjat et al.
Human infections with non-Helicobacter pylori Helicobacter species (NHPH) are rare. The diagnosis of such infection relies strongly on histological methods, as these bacteria cannot be easily cultured. We describe microbiological analyses t...
Investigation of OXA-48 Variants in Enterobacterales Isolates from an OXA-48-Endemic Region [0.03%]
OXA-48耐药菌株的流行病学及分子流行病学研究
Şevval Arduç Tok,Leyla Genç,Ayşe Barış et al.
Şevval Arduç Tok et al.
Since their first identification in Türkiye in 2001, OXA-48-like carbapenemases have posed diagnostic challenges due to variant-specific phenotypic and resistance profiles. We investigated the distribution of OXA-48 variants and their asso...
On-Farm Implementation of an Integrated Antimicrobial Stewardship Model in Pig Production: Effects on Antimicrobial Use and Resistance [0.03%]
生猪生产中综合抗菌药物管理模型的农场实施效果:对抗菌药物使用和抗性的效果研究
Kyung-Hyo Do,Da-Hye Ryu,Min-Gyu Kim et al.
Kyung-Hyo Do et al.
This study evaluated a 6-month, on-farm antimicrobial stewardship model integrating veterinary oversight, appropriate antimicrobial use, enhanced biosecurity, and an all-in/all-out system on five Korean pig farms lacking prior oversight. An...
Artificial Intelligence Applications in Antimicrobial Resistance: Comprehensive Review of Predictive Models, Diagnostic Innovations, and Clinical Integration [0.03%]
人工智能在抗微生物耐药性中的应用:预测模型、诊断创新和临床整合的全面回顾
Abdelaziz Touati,Fehmi Boufahja,Naoufel Ben Hamadi et al.
Abdelaziz Touati et al.
Antimicrobial resistance (AMR) represents a critical global health crisis, driving increased mortality, treatment failure, and economic burden. Artificial intelligence (AI) offers transformative potential to counter this threat by enhancing...
Itraconazole-Induced Apoptosis in Candida glabrata (Nakaseomyces glabratus) Biofilms: Role of ROS and CgPDR 1 Mutations (K274N, D1082G, and S343F) in Resistant Clinical Isolates [0.03%]
伊曲康唑诱导光滑假丝酵母(近平滑念珠菌)生物膜凋亡:临床耐药分离株中ROS和CgPDR 1突变(K274N,D1082G和S343F)的作用
Farnaz Valizadeh,Mahsa Fattahi,Ensieh Lotfali et al.
Farnaz Valizadeh et al.
Background: Nakaseomyces glabratus exhibits intrinsic tolerance to azole antifungals, frequently mediated by gain-of-function (GOF) mutations in the transcription factor CgPDR1. While efflux-mediated resistance is well es...
Carbapenem Resistance and Hypervirulence in Pediatric Klebsiella pneumoniae Sepsis [0.03%]
儿童肺炎克雷伯菌败血症中碳青霉烯耐药和高毒力的现象
Dina Mohammed Abdel-Hady,Mohamed Ahmed Noureldin,Maysaa El Sayed Zaki et al.
Dina Mohammed Abdel-Hady et al.
Background: Klebsiella pneumoniae is a major etiological agent of pediatric sepsis. The emergence and dissemination of carbapenem-resistant K. pneumoniae (CRKP) and hypervirulent strains (hvKp) represent an escalating glo...
Health Care-Associated Wound Infections and Antimicrobial Resistance in Earthquake Victims with Musculoskeletal Soft-Tissue Injuries: Experience from a Tertiary-Care Hospital [0.03%]
地震受害者肌肉骨骼软组织损伤相关的伤口感染及抗生素抗药性的住院经验研究
Semanur Kuzi,Gönül Çiçek Şentürk,Aslı Haykir Solay et al.
Semanur Kuzi et al.
Background and Objectives: Natural disasters increase the risk of wound infections due to factors such as trauma, invasive interventions, and delayed access to care. This study aimed to assess the epidemiology of health care-associated woun...
Analysis of Risk Factors and Resistance Genes for Carbapenem-Resistant Acinetobacter baumannii Bloodstream Infections: A Retrospective Study [0.03%]
碳青霉烯耐药鲍曼不动杆菌败血症的风险因素及耐药基因分析:回顾性研究
Jiahao Guan,Yajuan Ren,Xiaojun Dang et al.
Jiahao Guan et al.
Objective: The prevalence of carbapenem-resistant Acinetobacter baumannii (CRAb) has been increasing globally. This study aimed to investigate the risk factors, resistance gene profiles, and molecular epidemiology of CRAb...
Trends, Patterns, and Demographic Dynamics of Drug Resistance in Mycobacterium tuberculosis and Nontuberculous: A Multi-Year Analysis at the National Tuberculosis Reference Laboratory [0.03%]
耐多药结核分枝杆菌和非结核分枝杆菌的流行趋势及人群传播动态:国家结核病参比实验室多年监测分析
Sahar Sadeghi Mofrad,Mohsen Maleknia,Parissa Farnia et al.
Sahar Sadeghi Mofrad et al.
Background and objective: Drug-resistant (DR) mycobacterial infections present escalating threats in Iran, where facility-specific transmission dynamics and demographic disparities remain poorly characterized. This study ...
Ceftazidime-Avibactam/Colistin Combination Against Carbapenem-Resistant Pseudomonas aeruginosa: In Vitro Synergy Indicating a Possible Therapeutic Approach [0.03%]
舒巴坦-头孢他啶/多粘菌素B联合治疗碳青霉烯类耐药的铜绿假单胞菌:体外协同作用表明可能的治疗方法
Gulsah Altan,Devrim Dundar
Gulsah Altan
Background: The increasing prevalence of multidrug-resistant Pseudomonas aeruginosa limits treatment options and highlights the need for new antimicrobials. Although agents such as ceftazidime-avibactam (CZA), ceftolozane...